Loss of α1,6-fucosyltransferase inhibits chemical-induced hepatocellular carcinoma and tumorigenesis by down-regulating several cell signaling pathways

EGFR has a tumour-promoting role in liver macrophages during hepatocellular carcinoma formation

(2014) Hanane Lanaya et al.   NATURE CELL BIOLOGY

MiR-198 represses tumor growth and metastasis in colorectal cancer by targeting fucosyl transferase 8

(2014) Minyu Wang et al.   Scientific Reports

Targeting the HGF/c-MET Pathway in Hepatocellular Carcinoma

(2013) L. Goyal et al.   CLINICAL CANCER RESEARCH

α1,6-Fucosylation regulates neurite formation via the activin/phospho-Smad2 pathway in PC12 cells: the implicated dual effects of Fut8 for TGF-β/activin-mediated signaling

(2013) Wei Gu et al.   FASEB JOURNAL

Met as a therapeutic target in HCC: Facts and hopes

(2013) Silvia Giordano et al.   JOURNAL OF HEPATOLOGY

A Novel Core Fucose-specific Lectin from the MushroomPholiota squarrosa

(2012) Yuka Kobayashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fucosyltransferase 8 as a functional regulator of nonsmall cell lung cancer

(2012) C.-Y. Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Structural basis for improved efficacy of therapeutic antibodies on defucosylation of their Fc glycans

(2011) Tsunehiro Mizushima et al.   GENES TO CELLS

α1,6-Fucosyltransferase-deficient Mice Exhibit Multiple Behavioral Abnormalities Associated with a Schizophrenia-like Phenotype

(2011) Tomohiko Fukuda et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unique carbohydrate-carbohydrate interactions are required for high affinity binding between Fc RIII and antibodies lacking core fucose

(2011) C. Ferrara et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Systemic Treatment of Hepatocellular Carcinoma: Dawn of a New Era?

(2010) Andrew X. Zhu   ANNALS OF SURGICAL ONCOLOGY

Immunity, Inflammation, and Cancer

(2010) Sergei I. Grivennikov et al.   CELL

Molecular Imaging of N-linked Glycosylation Suggests Glycan Biosynthesis Is a Novel Target for Cancer Therapy

(2010) J. N. Contessa et al.   CLINICAL CANCER RESEARCH

Serum N-glycome biomarker for monitoring development of DENA-induced hepatocellular carcinoma in rat

(2010) Meng Fang et al.   Molecular Cancer

Novel Fucosylated Biomarkers for the Early Detection of Hepatocellular Carcinoma

(2009) M. Wang et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Transcription coactivator PBP/MED1-deficient hepatocytes are not susceptible to diethylnitrosamine-induced hepatocarcinogenesis in the mouse

(2009) K. Matsumoto et al.   CARCINOGENESIS

Hepatocyte Necrosis Induced by Oxidative Stress and IL-1α Release Mediate Carcinogen-Induced Compensatory Proliferation and Liver Tumorigenesis

(2008) Toshiharu Sakurai et al.   CANCER CELL

Mechanisms of Acquired Resistance to Epidermal Growth Factor Receptor Tyrosine Kinase Inhibitors in Non-Small Cell Lung Cancer

(2008) J. A. Engelman et al.   CLINICAL CANCER RESEARCH

Molecular mechanisms of hepatocellular carcinoma

(2008) Rajagopal N. Aravalli et al.   HEPATOLOGY

Molecular targeted therapies in hepatocellular carcinoma

(2008) Josep M. Llovet et al.   HEPATOLOGY

Expression and enzyme activity of α(1,6)fucosyltransferase in human colorectal cancer

(2008) Laura Muinelo-Romay et al.   INTERNATIONAL JOURNAL OF CANCER

Mechanisms of acquired resistance to cetuximab: role of HER (ErbB) family members

(2008) D L Wheeler et al.   ONCOGENE

Transforming Growth Factor β Controls the Directional Migration of Hepatocyte Cohorts by Modulating Their Adhesion to Fibronectin

(2007) Fabien Binamé et al.   MOLECULAR BIOLOGY OF THE CELL