Cell death mechanisms of the anti-cancer drug etoposide on human cardiomyocytes isolated from pluripotent stem cells

Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes

(2017) Liqun Zhao et al.   Scientific Reports

MicroRNAs as early toxicity signatures of doxorubicin in human-induced pluripotent stem cell-derived cardiomyocytes

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Protein–protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease

(2016) M. Khang Tran et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Co-delivery of etoposide and curcumin by lipid nanoparticulate drug delivery system for the treatment of gastric tumors

(2016) Hong Jiang et al.   DRUG DELIVERY

Bradycardia as a rare symptom of cisplatin cardiotoxicity: A case report

(2016) JAKUB KUCHARZ et al.   Oncology Letters

Identification of genomic biomarkers for anthracycline-induced cardiotoxicity in human iPSC-derived cardiomyocytes: an in vitro repeated exposure toxicity approach for safety assessment

(2015) Umesh Chaudhari et al.   ARCHIVES OF TOXICOLOGY

Etoposide induces cell death via mitochondrial-dependent actions of p53

(2015) Sarwat Jamil et al.   Cancer Cell International

Role of mitochondrial fission and fusion in cardiomyocyte contractility

(2015) S. Givvimani et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Targeting the sarcomere to correct muscle function

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A Novel Topoisomerase Inhibitor, Daurinol, Suppresses Growth of HCT116 Cells with Low Hematological Toxicity Compared to Etoposide

(2015) Kyungsu Kang et al.   NEOPLASIA

Mitochondrial fission is required for cardiomyocyte hypertrophy mediated by a Ca2+-calcineurin signaling pathway

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Drug attrition during pre-clinical and clinical development: Understanding and managing drug-induced cardiotoxicity

(2013) Nicola Ferri et al.   PHARMACOLOGY & THERAPEUTICS

Mitochondrial dynamics in the adult cardiomyocytes: which roles for a highly specialized cell?

(2013) Jerome Piquereau et al.   Frontiers in Physiology

Mitochondria as a Source of Reactive Oxygen and Nitrogen Species: From Molecular Mechanisms to Human Health

(2012) Tiago R. Figueira et al.   ANTIOXIDANTS & REDOX SIGNALING

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Dual Specificity Phosphatase 4 Mediates Cardiomyopathy Caused by Lamin A/C (LMNA) Gene Mutation

(2012) Jason C. Choi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuregulin1 as Novel Therapy for Heart Failure

(2011) Xinhua Yan et al.   CURRENT PHARMACEUTICAL DESIGN

Growth Differentiation Factor-15: a New Biomarker in Cardiovascular Disease

(2011) Tibor Kempf et al.   HERZ

miRWalk – Database: Prediction of possible miRNA binding sites by “walking” the genes of three genomes

(2011) Harsh Dweep et al.   JOURNAL OF BIOMEDICAL INFORMATICS

Mieap, a p53-Inducible Protein, Controls Mitochondrial Quality by Repairing or Eliminating Unhealthy Mitochondria

(2011) Noriaki Kitamura et al.   PLoS One

Role of ROS in ischemia-induced lung angiogenesis

(2010) Julie Nijmeh et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Etoposide-related cardiotoxicity in a child with haemophagocytic lymphohistiocytosis

(2010) Heather Escoto et al.   CARDIOLOGY IN THE YOUNG

Lomustine, etoposide, methotrexate and prednisone (LEMP) therapy for relapsed and refractory non-Hodgkin's lymphoma

(2010) A. Dorigo et al.   EUROPEAN JOURNAL OF HAEMATOLOGY

Topoisomerase IIα-dependent induction of a persistent DNA damage response in response to transient etoposide exposure

(2009) Sébastien Soubeyrand et al.   Molecular Oncology

p53 is required for etoposide-induced apoptosis of human embryonic stem cells

(2007) C. Grandela et al.   Stem Cell Research