Setd1a regulates progenitor B-cell-to-precursor B-cell development through histone H3 lysine 4 trimethylation and Ig heavy-chain rearrangement

The H3K4 methyltransferase Setd1a is first required at the epiblast stage, whereas Setd1b becomes essential after gastrulation

(2014) A. S. Bledau et al.   DEVELOPMENT

Distinct pathways regulated by menin and by MLL1 in hematopoietic stem cells and developing B cells

(2013) B. E. Li et al.   BLOOD

hSETD1A Regulates Wnt Target Genes and Controls Tumor Growth of Colorectal Cancer Cells

(2013) T. Salz et al.   CANCER RESEARCH

Aberrant TAL1 activation is mediated by an interchromosomal interaction in human T-cell acute lymphoblastic leukemia

(2013) B Patel et al.   LEUKEMIA

The MLL3/MLL4 Branches of the COMPASS Family Function as Major Histone H3K4 Monomethylases at Enhancers

(2013) D. Hu et al.   MOLECULAR AND CELLULAR BIOLOGY

Drosophila SETs Its Sights on Cancer: Trr/MLL3/4 COMPASS-Like Complexes in Development and Disease

(2013) Marc Alard Morgan et al.   MOLECULAR AND CELLULAR BIOLOGY

A network of epigenetic regulators guides developmental haematopoiesis in vivo

(2013) Hsuan-Ting Huang et al.   NATURE CELL BIOLOGY

An MLL-dependent network sustains hematopoiesis

(2013) E. L. Artinger et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

USF1 and hSET1A Mediated Epigenetic Modifications Regulate Lineage Differentiation and HoxB4 Transcription

(2013) Changwang Deng et al.   PLoS Genetics

The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis

(2012) Ali Shilatifard   Annual Review of Biochemistry

Noncoding transcription within the Igh distal VH region at PAIR elements affects the 3D structure of the Igh locus in pro-B cells

(2012) J. Verma-Gaur et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Pathogenesis of Mixed-Lineage Leukemia

(2011) Andrew G. Muntean et al.   Annual Review of Pathology-Mechanisms of Disease

Chromatin boundaries require functional collaboration between the hSET1 and NURF complexes

(2011) X. Li et al.   BLOOD

Two Forms of Loops Generate the Chromatin Conformation of the Immunoglobulin Heavy-Chain Gene Locus

(2011) Changying Guo et al.   CELL

DrosophilaSet1 is the major histone H3 lysine 4 trimethyltransferase with role in transcription

(2011) M Behfar Ardehali et al.   EMBO JOURNAL

The Distal VH Gene Cluster of the Igh Locus Contains Distinct Regulatory Elements with Pax5 Transcription Factor-Dependent Activity in Pro-B Cells

(2011) Anja Ebert et al.   IMMUNITY

H4R3 methylation facilitates  -globin transcription by regulating histone acetyltransferase binding and H3 acetylation

(2010) X. Li et al.   BLOOD

The In Vivo Pattern of Binding of RAG1 and RAG2 to Antigen Receptor Loci

(2010) Yanhong Ji et al.   CELL

Developmentally induced Mll1 loss reveals defects in postnatal haematopoiesis

(2010) T Gan et al.   LEUKEMIA

Epigenetic and 3-dimensional regulation of V(D)J rearrangement of immunoglobulin genes

(2010) Stephanie C. Degner-Leisso et al.   SEMINARS IN IMMUNOLOGY

Global Analysis of H3K4 Methylation Defines MLL Family Member Targets and Points to a Role for MLL1-Mediated H3K4 Methylation in the Regulation of Transcriptional Initiation by RNA Polymerase II

(2009) P. Wang et al.   MOLECULAR AND CELLULAR BIOLOGY

Loss of Mll5 results in pleiotropic hematopoietic defects, reduced neutrophil immune function, and extreme sensitivity to DNA demethylation

(2008) M. Heuser et al.   BLOOD

Impaired function of primitive hematopoietic cells in mice lacking the Mixed-Lineage-Leukemia homolog Mll5

(2008) V. Madan et al.   BLOOD

The 3D Structure of the Immunoglobulin Heavy-Chain Locus: Implications for Long-Range Genomic Interactions

(2008) Suchit Jhunjhunwala et al.   CELL