Tyrosine phosphorylation of RAS by ABL allosterically enhances effector binding

Allosteric Effects of the Oncogenic RasQ61L Mutant on Raf-RBD

(2015) Susan K. Fetics et al.   STRUCTURE

Src promotes GTPase activity of Ras via tyrosine 32 phosphorylation

(2014) S. Bunda et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

DRoP: A Water Analysis Program Identifies Ras-GTP-Specific Pathway of Communication between Membrane-Interacting Regions and the Active Site

(2013) Bradley M. Kearney et al.   JOURNAL OF MOLECULAR BIOLOGY

Phosphorylated K-Ras limits cell survival by blocking Bcl-xL sensitization of inositol trisphosphate receptors

(2013) P. J. Sung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Comprehensive Survey of Ras Mutations in Cancer

(2012) I. A. Prior et al.   CANCER RESEARCH

RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR

(2012) K. Balaji et al.   JOURNAL OF CELL SCIENCE

Ras Stabilization Through Aberrant Activation of Wnt/ -Catenin Signaling Promotes Intestinal Tumorigenesis

(2012) W.-J. Jeong et al.   Science Signaling

Overexpression of RIN1 associates with tumor grade and progression in patients of bladder urothelial carcinoma

(2012) Guang-yi Shan et al.   TUMOR BIOLOGY

High RIN1 expression is associated with poor prognosis in patients with gastric adenocarcinoma

(2012) Hai-Feng Yu et al.   TUMOR BIOLOGY

RIN1 exhibits oncogenic property to suppress apoptosis and its aberrant accumulation associates with poor prognosis in melanoma

(2012) Ping Fang et al.   TUMOR BIOLOGY

Prognostic significance of RIN1 gene expression in human non-small cell lung cancer

(2011) Qun Wang et al.   ACTA HISTOCHEMICA

Analysis of Binding Site Hot Spots on the Surface of Ras GTPase

(2011) Greg Buhrman et al.   JOURNAL OF MOLECULAR BIOLOGY

Regulating the regulator: post-translational modification of RAS

(2011) Ian M. Ahearn et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Ubiquitination of K-Ras Enhances Activation and Facilitates Binding to Select Downstream Effectors

(2011) A. T. Sasaki et al.   Science Signaling

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Feedback Regulation of Ras Signaling by Rabex-5-Mediated Ubiquitination

(2010) Lizhong Xu et al.   CURRENT BIOLOGY

Allosteric Modulation of Ras-GTP Is Linked to Signal Transduction through RAF Kinase

(2010) Greg Buhrman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Activation of Aortic Endothelial Cells by Oxidized Phospholipids: A Phosphoproteomic Analysis

(2010) Alejandro Zimman et al.   JOURNAL OF PROTEOME RESEARCH

ABL fusion oncogene transformation and inhibitor sensitivity are mediated by the cellular regulator RIN1

(2010) M Thai et al.   LEUKEMIA

Allosteric modulation of Ras positions Q61 for a direct role in catalysis

(2010) G. Buhrman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

ABL Tyrosine Kinases: Evolution of Function, Regulation, and Specificity

(2010) J. Colicelli   Science Signaling

Cell Proliferation and Epidermal Growth Factor Signaling in Non-small Cell Lung Adenocarcinoma Cell Lines Are Dependent on Rin1

(2009) Jin C. Tomshine et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulated expression of the Ras effector Rin1 in forebrain neurons

(2009) Bartholomew Dzudzor et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Enhancement of ABL Kinase Catalytic Efficiency by a Direct Binding Regulator Is Independent of Other Regulatory Mechanisms

(2008) Xiaoqing Cao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prediction of phosphotyrosine signaling networks using a scoring matrix-assisted ligand identification approach

(2008) Lei Li et al.   NUCLEIC ACIDS RESEARCH