Yeast-based genotoxicity tests for assessing DNA alterations and DNA stress responses: a 40-year overview

An in vitro system for measuring genotoxicity mediated by human CYP3A4 in Saccharomyces cerevisiae

(2017) Michael Fasullo et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Development and evaluation of yeast-based GFP and luciferase reporter assays for chemical-induced genotoxicity and oxidative damage

(2016) Hajime Suzuki et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

A Quantitative Toxicogenomics Assay for High-throughput and Mechanistic Genotoxicity Assessment and Screening of Environmental Pollutants

(2016) Jiaqi Lan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Procarcinogens – Determination and Evaluation by Yeast-Based Biosensor Transformed with Plasmids Incorporating RAD54 Reporter Construct and Cytochrome P450 Genes

(2016) Van Ngoc Bui et al.   PLoS One

Yeast Biosensors for Detection of Environmental Pollutants: Current State and Limitations

(2016) Sergio Jarque et al.   TRENDS IN BIOTECHNOLOGY

Genotoxicity of Chemical Compounds Identification and Assessment by Yeast Cells Transformed With GFP Reporter Constructs Regulated by the PLM2 or DIN7 Promoter

(2015) Van Ngoc Bui et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Dual fluorescent protein-based bioassay system for the detection of genotoxic chemical substances in Saccharomyces cerevisiae

(2015) Yixin Lu et al.   TOXICOLOGY MECHANISMS AND METHODS

Dual fluorescent protein-based bioassay system for the detection of genotoxic chemical substances in Saccharomyces cerevisiae

(2015) Yixin Lu et al.   TOXICOLOGY MECHANISMS AND METHODS

Comparative and Mechanistic Genotoxicity Assessment of Nanomaterials via a Quantitative Toxicogenomics Approach across Multiple Species

(2014) Jiaqi Lan et al.   ENVIRONMENTAL SCIENCE & TECHNOLOGY

Construction and evaluation of two biosensors based on yeast transcriptional response to genotoxic chemicals

(2013) Ting Wei et al.   BIOSENSORS & BIOELECTRONICS

A multistep genomic screen identifies new genes required for repair of DNA double-strand breaks in Saccharomyces cerevisiae

(2013) Jennifer Summers McKinney et al.   BMC GENOMICS

Assessment of yeast chromosome XII instability: Single chromosome comet assay

(2013) Anna Lewinska et al.   FUNGAL GENETICS AND BIOLOGY

Validation of a human cell based high-throughput genotoxicity assay ‘Anthem’s Genotoxicity screen’ using ECVAM recommended lists of genotoxic and non-genotoxic chemicals

(2013) Lakshmi Rajakrishna et al.   TOXICOLOGY IN VITRO

DNA Damage Responses in Prokaryotes: Regulating Gene Expression, Modulating Growth Patterns, and Manipulating Replication Forks

(2013) K. N. Kreuzer   Cold Spring Harbor Perspectives in Biology

Yeast as a Humanized Model Organism for Biotransformation-Related Toxicity

(2012) Jolanda S. van Leeuwen et al.   CURRENT DRUG METABOLISM

Genotoxicity evaluation of effluents from textile industries of the region Fez-Boulmane, Morocco: A case study

(2011) Lucia Giorgetti et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

The ToxTracker Assay: Novel GFP Reporter Systems that Provide Mechanistic Insight into the Genotoxic Properties of Chemicals

(2011) Giel Hendriks et al.   TOXICOLOGICAL SCIENCES

Microscreening toxicity system based on living magnetic yeast and gradient chips

(2010) Javier García-Alonso et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Genome-Wide Expression Changes in Saccharomyces cerevisiae in Response to High-LET Ionizing Radiation

(2010) Satomi Mizukami-Murata et al.   APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY

New in vitro reporter gene bioassays for screening of hormonal active compounds in the environment

(2010) Kateřina Svobodová et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

The positive response of Ty1 retrotransposition test to carcinogens is due to increased levels of reactive oxygen species generated by the genotoxins

(2010) Martin Dimitrov et al.   ARCHIVES OF TOXICOLOGY

Genotoxicity of 4-nonylphenol and nonylphenol ethoxylate mixtures by the use of Saccharomyces cerevisiae D7 mutation assay and use of this text to evaluate the efficiency of biodegradation treatments

(2010) Stefania Frassinetti et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Seasonally and regionally determined indication potential of bioassays in contaminated river sediments

(2010) Klára Hilscherová et al.   ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY

Inactivation of YAP1 Enhances Sensitivity of the Yeast RNR3-lacZ Genotoxicity Testing System to a Broad Range of DNA-Damaging Agents

(2010) Min Zhang et al.   TOXICOLOGICAL SCIENCES

Measuring oxidative DNA damage and DNA repair using the yeast comet assay

(2010) Flávio Azevedo et al.   YEAST

Sensitive detection of chemical-induced genotoxicity by the Cypridina secretory luciferase reporter assay, using DNA repair-deficient strains of Saccharomyces cerevisiae

(2010) Yukari Ochi et al.   YEAST

Benzene-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the functional analysis of separated alleles in yeast, in human lung cells

(2009) Sylvain Billet et al.   ARCHIVES OF TOXICOLOGY

Genetic Polymorphism of Metabolic Enzymes P450 (CYP) as a Susceptibility Factor for Drug Response, Toxicity, and Cancer Risk

(2009) Nada Božina et al.   Arhiv za Higijenu Rada i Toksikologiju-Archives of Industrial Hygiene and Toxicology

Rapid and direct magnetization of GFP-reporter yeast for micro-screening systems

(2009) Javier García-Alonso et al.   BIOSENSORS & BIOELECTRONICS

Evaluation of the Vitotox™ and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development

(2009) Walter M.A. Westerink et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

The development of RAD51C, Cystatin A, p53 and Nrf2 luciferase-reporter assays in metabolically competent HepG2 cells for the assessment of mechanism-based genotoxicity and of oxidative stress in the early research phase of drug development

(2009) Walter M.A. Westerink et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Creation of a Hyperpermeable Yeast Strain to Genotoxic Agents through Combined Inactivation of PDR and CWP Genes

(2009) Min Zhang et al.   TOXICOLOGICAL SCIENCES

The response of Ty1 test to genotoxins

(2008) M. Pesheva et al.   ARCHIVES OF TOXICOLOGY

Deletion of MAG1 and MRE11 enhances the sensitivity of the Saccharomyces cerevisiae HUG1P-GFP promoter-reporter construct to genotoxicity

(2008) Michael G. Benton et al.   BIOSENSORS & BIOELECTRONICS

A prototype microfluidic chip using fluorescent yeast for detection of toxic compounds

(2008) Javier García-Alonso et al.   BIOSENSORS & BIOELECTRONICS

Aflatoxin B1-induced TP53 mutational pattern in normal human cells using the FASAY (Functional Analysis of Separated Alleles in Yeast)

(2008) Vincent Paget et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Development of a highthroughput yeast-based assay for detection of metabolically activated genotoxins

(2008) Xuemei Liu et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Comet assay on tetraploid yeast cells

(2008) Jette Rank et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Deletion of Yeast CWP Genes Enhances Cell Permeability to Genotoxic Agents

(2008) Min Zhang et al.   TOXICOLOGICAL SCIENCES

Genotoxicity of leachates from highly polluted lowland river sediments destined for disposal in landfill

(2008) Anahi Magdaleno et al.   WASTE MANAGEMENT

Acetaldehyde-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the FASAY (functional analysis of separated alleles in yeast)

(2007) Vincent Paget et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

A novel yeast-based tool to detect mutagenic and recombinogenic effects simultaneously

(2007) B. Schafer et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS