CTLA-4Ig (abatacept) balances bone anabolic effects of T cells and Wnt-10b with antianabolic effects of osteoblastic sclerostin

Physiological and pathophysiological bone turnover — role of the immune system

(2016) M. Neale Weitzmann et al.   Nature Reviews Endocrinology

T Cell-Expressed CD40L Potentiates the Bone Anabolic Activity of Intermittent PTH Treatment

(2015) Jerid W Robinson et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Evolutionary medicine and bone loss in chronic inflammatory diseases—A theory of inflammation-related osteopenia

(2015) Rainer H. Straub et al.   SEMINARS IN ARTHRITIS AND RHEUMATISM

T Cell Costimulation Molecules CD80/86 Inhibit Osteoclast Differentiation by Inducing the IDO/Tryptophan Pathway

(2014) A. Bozec et al.   Science Translational Medicine

Dysregulated B Cell Expression of RANKL and OPG Correlates with Loss of Bone Mineral Density in HIV Infection

(2014) Kehmia Titanji et al.   PLoS Pathogens

CTLA-4Ig-Induced T Cell Anergy Promotes Wnt-10b Production and Bone Formation in a Mouse Model

(2014) Susanne Roser-Page et al.   Arthritis & Rheumatology

The Sclerostin-Independent Bone Anabolic Activity of Intermittent PTH Treatment Is Mediated by T-Cell-Produced Wnt10b

(2013) Jau-Yi Li et al.   JOURNAL OF BONE AND MINERAL RESEARCH

An integrated understanding of the physiological response to elevated extracellular phosphate

(2013) Corinne E. Camalier et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Silencing of parathyroid hormone (PTH) receptor 1 in T cells blunts the bone anabolic activity of PTH

(2012) B. Bedi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Inhibition of antigen presentation and T cell costimulation blocks PTH-induced bone loss

(2010) Brahmchetna Bedi et al.   Annals of the New York Academy of Sciences

Wnt10b deficiency results in age-dependent loss of bone mass and progressive reduction of mesenchymal progenitor cells

(2010) Jennifer R Stevens et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Guidelines for assessment of bone microstructure in rodents using micro-computed tomography

(2010) Mary L Bouxsein et al.   JOURNAL OF BONE AND MINERAL RESEARCH

T Lymphocytes Amplify the Anabolic Activity of Parathyroid Hormone through Wnt10b Signaling

(2009) Masakazu Terauchi et al.   Cell Metabolism

CTLA-4 directly inhibits osteoclast formation

(2008) R Axmann et al.   ANNALS OF THE RHEUMATIC DISEASES

T Cells Potentiate PTH-Induced Cortical Bone Loss through CD40L Signaling

(2008) Yuhao Gao et al.   Cell Metabolism