Biomarker development for presymptomatic molecular diagnosis of preeclampsia: feasible, useful or even unnecessary?

Cardiovascular Disease Risk Factors After Early-Onset Preeclampsia, Late-Onset Preeclampsia, and Pregnancy-Induced HypertensionNovelty and Significance

(2015) Jan H.W. Veerbeek et al.   HYPERTENSION

Residential proximity to major roads and obstetrical complications

(2015) Takashi Yorifuji et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Expression of markers of endoplasmic reticulum stress-induced apoptosis in the placenta of women with early and late onset severe pre-eclampsia

(2015) Jinhua Fu et al.   Taiwanese Journal of Obstetrics & Gynecology

Reduced uterine perfusion pressure induces hypertension in the pregnant mouse

(2014) Suttira Intapad et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Low-Dose Aspirin Use for the Prevention of Morbidity and Mortality From Preeclampsia: U.S. Preventive Services Task Force Recommendation Statement

(2014) Michael L. LeFevre   ANNALS OF INTERNAL MEDICINE

Noninvasive Prenatal Diagnosis: From Dream to Reality

(2014) Y. M. D. Lo   CLINICAL CHEMISTRY

Development of the hemochorial maternal vascular spaces in the placenta through endothelial and vasculogenic mimicry

(2014) Anshita Rai et al.   DEVELOPMENTAL BIOLOGY

Clinical proteomics in obstetrics and neonatology

(2014) Julie Klein et al.   Expert Review of Proteomics

A1M, an extravascular tissue cleaning and housekeeping protein

(2014) Bo Åkerström et al.   FREE RADICAL BIOLOGY AND MEDICINE

Elevation of Urinary Adipsin in Preeclampsia

(2014) Tao Wang et al.   HYPERTENSION

Inflammation in rat pregnancy inhibits spiral artery remodeling leading to fetal growth restriction and features of preeclampsia

(2014) Tiziana Cotechini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The use and misuse of animal analog models of human pregnancy disorders

(2014) David A. Clark   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Cell-free nucleic acids in (maternal) blood: any relevance to (reproductive) immunologists?

(2014) Sinuhe Hahn et al.   JOURNAL OF REPRODUCTIVE IMMUNOLOGY

Energy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development

(2014) T. Cindrova-Davies et al.   MOLECULAR HUMAN REPRODUCTION

Low-dose aspirin to reduce the risk of pre-eclampsia?

(2014) Baha M. Sibai   Nature Reviews Endocrinology

Pre-eclampsia part 1: current understanding of its pathophysiology

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Pre-eclampsia part 2: prediction, prevention and management

(2014) Tinnakorn Chaiworapongsa et al.   Nature Reviews Nephrology

Maternal Morbidity Associated With Early-Onset and Late-Onset Preeclampsia

(2014) Sarka Lisonkova et al.   OBSTETRICS AND GYNECOLOGY

Evolutionary origins of the placental expression of chromosome 19 cluster galectins and their complex dysregulation in preeclampsia

(2014) N.G. Than et al.   PLACENTA

Inflammation-induced fetal growth restriction in rats is associated with altered placental morphometrics

(2014) T. Cotechini et al.   PLACENTA

The Human Placenta Project: Placental structure, development, and function in real time

(2014) A.E. Guttmacher et al.   PLACENTA

IFPA Senior Award Lecture: Making sense of pre-eclampsia – Two placental causes of preeclampsia?

(2014) C.W. Redman et al.   PLACENTA

A1M/α1-Microglobulin Protects from Heme-Induced Placental and Renal Damage in a Pregnant Sheep Model of Preeclampsia

(2014) Lena Wester-Rosenlöf et al.   PLoS One

Carbon Monoxide Prevents Hypertension and Proteinuria in an Adenovirus sFlt-1 Preeclampsia-Like Mouse Model

(2014) Carolina C. Venditti et al.   PLoS One

In Vivo Experiments Reveal the Good, the Bad and the Ugly Faces of sFlt-1 in Pregnancy

(2014) Gabor Szalai et al.   PLoS One

Including ethical considerations in models for first-trimester screening for pre-eclampsia

(2014) J.M. Jørgensen et al.   REPRODUCTIVE BIOMEDICINE ONLINE

A unified approach to risk assessment for fetal aneuploidies

(2014) D. Wright et al.   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

Controlling the Immunological Crosstalk during Conception and Pregnancy: HLA-G in Reproduction

(2014) Line Lynge Nilsson et al.   Frontiers in Immunology

Innate and Adaptive Immune Interactions at the Fetal–Maternal Interface in Healthy Human Pregnancy and Pre-Eclampsia

(2014) Peter Hsu et al.   Frontiers in Immunology

The Role of Placental Tryptophan Catabolism

(2014) Peter Sedlmayr et al.   Frontiers in Immunology

Placental Protein 13 (PP13) – A Placental Immunoregulatory Galectin Protecting Pregnancy

(2014) Nándor Gábor Than et al.   Frontiers in Immunology

Complement Activation and Regulation in Preeclamptic Placenta

(2014) Anna Inkeri Lokki et al.   Frontiers in Immunology

New Developments in the Pathogenesis of Preeclampsia

(2013) Mihran V. Naljayan et al.   ADVANCES IN CHRONIC KIDNEY DISEASE

What to expect from expectant management in severe preeclampsia at

(2013) Baha M. Sibai   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Incidence of preeclampsia: risk factors and outcomes associated with early- versus late-onset disease

(2013) Sarka Lisonkova et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Transthyretin Is Dysregulated in Preeclampsia, and Its Native Form Prevents the Onset of Disease in a Preclinical Mouse Model

(2013) Satyan S. Kalkunte et al.   AMERICAN JOURNAL OF PATHOLOGY

Does screening for pre-eclampsia make sense?

(2013) C Hyde et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Integration of Noninvasive DNA Testing for Aneuploidy into Prenatal Care: What Has Happened Since the Rubber Met the Road?

(2013) D. W. Bianchi et al.   CLINICAL CHEMISTRY

Placental protein 13 (PP13): a new biological target shifting individualized risk assessment to personalized drug design combating pre-eclampsia

(2013) B. Huppertz et al.   HUMAN REPRODUCTION UPDATE

Preeclampsia Is Associated With the Presence of Transcriptionally Active Placental Fragments in the Maternal Lung

(2013) Aletta J. Buurma et al.   HYPERTENSION

Integrated Proteomics Pipeline Yields Novel Biomarkers for Predicting Preeclampsia

(2013) Jenny E. Myers et al.   HYPERTENSION

New Gestational Phase–Specific Cutoff Values for the Use of the Soluble fms-Like Tyrosine Kinase-1/Placental Growth Factor Ratio as a Diagnostic Test for Preeclampsia

(2013) Stefan Verlohren et al.   HYPERTENSION

Differences and similarities in the transcriptional profile of peripheral whole blood in early and late-onset preeclampsia: insights into the molecular basis of the phenotype of preeclampsiaa

(2013) Tinnakorn Chaiworapongsa et al.   JOURNAL OF PERINATAL MEDICINE

Quantifying protein interaction dynamics by SWATH mass spectrometry: application to the 14-3-3 system

(2013) Ben C Collins et al.   NATURE METHODS

Evaluation of Current and New Biomarkers in Severe Preeclampsia: A Microarray Approach Reveals the VSIG4 Gene as a Potential Blood Biomarker

(2013) Julien Textoris et al.   PLoS One

PTX3 as a paradigm for the interaction of pentraxins with the Complement system

(2013) Antonio Inforzato et al.   SEMINARS IN IMMUNOLOGY

Risk of future cardiovascular disease in women with prior preeclampsia: a focus group study

(2013) Ellen W Seely et al.   BMC Pregnancy and Childbirth

A multi-centre phase IIa clinical study of predictive testing for preeclampsia: improved pregnancy outcomes via early detection (IMPROvED)

(2013) Kate Navaratnam et al.   BMC Pregnancy and Childbirth

Molecular genetics of preeclampsia and HELLP syndrome — A review

(2012) Jiska Jebbink et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Circulating ficolin-2 and ficolin-3 in normal pregnancy and pre-eclampsia

(2012) A. Halmos et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Microarray Screening for Novel Preeclampsia Biomarker Candidates

(2012) Olav Lapaire et al.   FETAL DIAGNOSIS AND THERAPY

Preeclampsia Is Characterized by Placental Complement Dysregulation

(2012) Aletta Buurma et al.   HYPERTENSION

Air Pollution During Pregnancy and Neonatal Outcome: A Review

(2012) Elena Proietti et al.   Journal of Aerosol Medicine and Pulmonary Drug Delivery

Quantitative Proteomic (iTRAQ) Analysis of 1st Trimester Maternal Plasma Samples in Pregnancies at Risk for Preeclampsia

(2012) Varaprasad Kolla et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Late-onset preeclampsia is associated with an imbalance of angiogenic and anti-angiogenic factors in patients with and without placental lesions consistent with maternal underperfusion

(2012) Eleazar Soto et al.   Journal of Maternal-Fetal & Neonatal Medicine

Review: Does size matter? Placental debris and the pathophysiology of pre-eclampsia

(2012) C.W.G. Redman et al.   PLACENTA

IFPA Meeting 2012 Workshop Report I: Comparative placentation and animal models, advanced techniques in placental histopathology, human pluripotent stem cells as a model for trophoblast differentiation

(2012) W.E. Ackerman et al.   PLACENTA

Eculizumab for the treatment of preeclampsia/HELLP syndrome

(2012) R.M. Burwick et al.   PLACENTA

Can detection of late-onset PE at triage by sflt-1 or PlGF be improved by the use of additional biomarkers?

(2012) Ines Kaufmann et al.   PRENATAL DIAGNOSIS

Preeclampsia: A multi-stress disorder

(2012) C.W.G. Redman   REVUE DE MEDECINE INTERNE

Maternal Mortality From Preeclampsia/Eclampsia

(2012) Labib Ghulmiyyah et al.   SEMINARS IN PERINATOLOGY

Neutrophil NETs in reproduction: from infertility to preeclampsia and the possibility of fetal loss

(2012) Sinuhe Hahn et al.   Frontiers in Immunology

Etiology and management of postpartum hypertension-preeclampsia

(2011) Baha M. Sibai   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

The genetics of pre-eclampsia and other hypertensive disorders of pregnancy

(2011) Paula J. Williams et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Turning the Pyramid of Prenatal Care

(2011) Kypros H. Nicolaides   FETAL DIAGNOSIS AND THERAPY

Role of Complement Component C1q in the Onset of Preeclampsia in Mice

(2011) Jameel Singh et al.   HYPERTENSION

Placental lesions associated with maternal underperfusion are more frequent in early-onset than in late-onset preeclampsia

(2011) Giovanna Ogge et al.   JOURNAL OF PERINATAL MEDICINE

Translational Analysis of Mouse and Human Placental Protein and mRNA Reveals Distinct Molecular Pathologies in Human Preeclampsia

(2011) Brian Cox et al.   MOLECULAR & CELLULAR PROTEOMICS

PP13, Maternal ABO Blood Groups and the Risk Assessment of Pregnancy Complications

(2011) Nandor Gabor Than et al.   PLoS One

Syncytiotrophoblast Microvesicles Released from Pre-Eclampsia Placentae Exhibit Increased Tissue Factor Activity

(2011) Chris Gardiner et al.   PLoS One

Prediction of early, intermediate and late pre-eclampsia from maternal factors, biophysical and biochemical markers at 11-13 weeks

(2011) Ranjit Akolekar et al.   PRENATAL DIAGNOSIS

A model for a new pyramid of prenatal care based on the 11 to 13 weeks' assessment

(2011) Kypros H. Nicolaides   PRENATAL DIAGNOSIS

Comparative studies of placentation and immunology in non-human primates suggest a scenario for the evolution of deep trophoblast invasion and an explanation for human pregnancy disorders

(2011) Anthony M Carter   REPRODUCTION

Placental Protein 13 and Decidual Zones of Necrosis: An Immunologic Diversion That May be Linked to Preeclampsia

(2011) Harvey J. Kliman et al.   Reproductive Sciences

The “Great Obstetrical Syndromes” are associated with disorders of deep placentation

(2010) Ivo Brosens et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Evolution of invasive placentation with special reference to non-human primates

(2010) Anthony M. Carter et al.   BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY

Gene Expression in First Trimester Preeclampsia Placenta

(2010) Sandra A. Founds et al.   Biological Research for Nursing

Different profiles of circulating angiogenic factors and adipocytokines between early- and late-onset pre-eclampsia

(2010) H Masuyama et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Super-obesity and risk for early and late pre-eclampsia

(2010) AK Mbah et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Late Onset Preeclampsia is not an Innocuous Condition

(2010) L. Kenneth et al.   HYPERTENSION IN PREGNANCY

Quantitative Proteomics Analysis of Maternal Plasma in Down Syndrome Pregnancies Using Isobaric Tagging Reagent (iTRAQ)

(2010) Varaprasad Kolla et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Pre-eclampsia

(2010) Eric AP Steegers et al.   LANCET

Dysregulated Complement Activation as a Common Pathway of Injury in Preeclampsia and Other Pregnancy Complications

(2010) A.M. Lynch et al.   PLACENTA

A New Mouse Model to Explore Therapies for Preeclampsia

(2010) Abdulwahab Ahmed et al.   PLoS One

Extracellular DNA traps promote thrombosis

(2010) T. A. Fuchs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

First-trimester screening for pre-eclampsia and fetal growth restriction: a test seeking both a treatment and an optimal timing

(2010) C. Lees   ULTRASOUND IN OBSTETRICS & GYNECOLOGY

First trimester PTX3 levels in women who subsequently develop preeclampsia and fetal growth restriction

(2009) Irene Cetin et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA

An automated method for the determination of the sFlt-1/PIGF ratio in the assessment of preeclampsia

(2009) Stefan Verlohren et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Systematic analysis of research underfunding in maternal and perinatal health

(2009) NM Fisk et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Proteomic technologies for prenatal diagnostics: advances and challenges ahead

(2009) Mahesh Choolani et al.   Expert Review of Proteomics

Comparative systems biology of human and mouse as a tool to guide the modeling of human placental pathology

(2009) Brian Cox et al.   Molecular Systems Biology

Maternal plasma pentraxin 3 at 11 to 13 weeks of gestation in hypertensive disorders of pregnancy

(2009) Ranjit Akolekar et al.   PRENATAL DIAGNOSIS

First trimester maternal serum placental protein 13 for the prediction of pre-eclampsia in women witha priorihigh risk

(2009) Asma Khalil et al.   PRENATAL DIAGNOSIS

Maternal serum placental protein 13 at 11–13 weeks of gestation in preeclampsia

(2009) Ranjit Akolekar et al.   PRENATAL DIAGNOSIS

A primate subfamily of galectins expressed at the maternal-fetal interface that promote immune cell death

(2009) N. G. Than et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Imitators of Severe Pre-eclampsia

(2009) Baha M. Sibai   SEMINARS IN PERINATOLOGY

First-trimester maternal serum PP13 in the risk assessment for preeclampsia

(2008) Roberto Romero et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Alternative complement pathway activation fragment Bb in early pregnancy as a predictor of preeclampsia

(2008) Anne M. Lynch et al.   AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY

Reduced Selenium Concentrations and Glutathione Peroxidase Activity in Preeclamptic Pregnancies

(2008) Hiten D. Mistry et al.   HYPERTENSION

Angiotensin receptor agonistic autoantibodies induce pre-eclampsia in pregnant mice

(2008) Cissy C Zhou et al.   NATURE MEDICINE

Altered Global Gene Expression in First Trimester Placentas of Women Destined to Develop Preeclampsia

(2008) S.A. Founds et al.   PLACENTA

PP13 mRNA Expression in Trophoblasts From Preeclamptic Placentas

(2008) Akihiko Sekizawa et al.   Reproductive Sciences

Seasonal influence on the admittance of pre-eclampsia patients in Tygerberg Hospital

(2007) Annelies Immink et al.   ACTA OBSTETRICIA ET GYNECOLOGICA SCANDINAVICA