Lipopolysaccharide challenge: immunological effects and safety in humans

A Randomized Controlled Trial of Peripheral Blood Mononuclear Cell Depletion in Experimental Human Lung Inflammation

(2013) Laura C. Barr et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Airborne Allergens, Endotoxins, and Particulate Matter in Elementary Schools, Results from Germany (LUPE 2)

(2013) Hermann Fromme et al.   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL HYGIENE

Inhibition of LPS-induced airway neutrophilic inflammation in healthy volunteers with an oral CXCR2 antagonist

(2013) Brian R Leaker et al.   RESPIRATORY RESEARCH

Low-dose endotoxin inhalation in healthy volunteers - a challenge model for early clinical drug development

(2013) Ole Janssen et al.   BMC Pulmonary Medicine

Inhaled LPS challenges in smokers: a study of pulmonary and systemic effects

(2012) Raminder Aul et al.   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

A novel subpopulation of monocyte-like cells in the human lung after lipopolysaccharide inhalation

(2012) Mairi Brittan et al.   EUROPEAN RESPIRATORY JOURNAL

LPS challenge in healthy subjects: An investigation of neutrophil chemotaxis mechanisms involving CXCR1 and CXCR2

(2012) Raminder Aul et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Atopic asthmatic patients have reduced airway inflammatory cell recruitment after inhaled endotoxin challenge compared with healthy volunteers

(2012) Michelle L. Hernandez et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Differential Inflammatory Response to Inhaled Lipopolysaccharide Targeted Either to the Airways or the Alveoli in Man

(2012) Winfried Möller et al.   PLoS One

Airway inflammation evaluated in a human nasal lipopolysaccharide challenge model by investigating the effect of a CXCR2 inhibitor

(2011) R. Virtala et al.   CLINICAL AND EXPERIMENTAL ALLERGY

Inhalation of LPS induces inflammatory airway responses mimicking characteristics of chronic obstructive pulmonary disease

(2011) Magnus Korsgren et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

Time Course of Endotoxin-Induced Airways’ Inflammation in Healthy Subjects

(2011) Virginie Doyen et al.   INFLAMMATION

Bronchial Allergen Challenge Using the Medicaid Dosimeter

(2011) Johannes Schulze et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

Interleukin-17-producing T-helper cells and related cytokines in human airways exposed to endotoxin

(2010) P. Glader et al.   EUROPEAN RESPIRATORY JOURNAL

Simvastatin Decreases Lipopolysaccharide-induced Pulmonary Inflammation in Healthy Volunteers

(2009) Murali Shyamsundar et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Toll-like receptor 4 variants reduce airway response in human subjects at high endotoxin levels in a swine facility

(2009) Ambikaipakan Senthilselvan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Methacholine challenge – Comparison of an ATS protocol to a new rapid single concentration technique

(2009) Johannes Schulze et al.   RESPIRATORY MEDICINE

Increase in proinflammatory cytokines in peripheral blood without haemostatic changes after LPS inhalation

(2009) Marc Fouassier et al.   THROMBOSIS RESEARCH

Health effects due to endotoxin inhalation (review)

(2008) V. Liebers et al.   ARCHIVES OF TOXICOLOGY

Fluticasone and ibuprofen do not add to the effect of salmeterol on organic dust-induced airway inflammation and bronchial hyper-responsiveness

(2008) K. Strandberg et al.   JOURNAL OF INTERNAL MEDICINE

Pulmonary and systemic effects of inhaled endotoxin in control and heaves horses

(2007) R. S. PIRIE et al.   EQUINE VETERINARY JOURNAL

Association between CD14 polymorphisms and serum soluble CD14 levels: Effect of atopy and endotoxin inhalation

(2007) Tricia D. LeVan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY