期刊
EXPERT REVIEW OF ANTI-INFECTIVE THERAPY
卷 13, 期 12, 页码 1517-1535出版社
TAYLOR & FRANCIS LTD
DOI: 10.1586/14787210.2015.1096775
关键词
acute respiratory infection; adverse events; antibiotic-associated diarrhea; childhood; diarrhea; Helicobacter pylori; infectious diseases; NEC; probiotics; urinary tract infection
We summarize current evidence and recommendations for the use of probiotics in childhood infectious diseases. Probiotics may be of benefit in treating acute infectious diarrhea and reducing antibiotic-associated diarrhea. Potential benefits of probiotic on prevention of traveler's diarrhea,Clostridium difficile-associated diarrhea, side effects of triple therapy in Helicobacter pylori eradication, necrotizing enterocolitis, acute diarrhea, acute respiratory infections and recurrent urinary tract infections remain unclear. More studies are needed to investigate optimal strain, dosage, bioavailability of drops and tablets, duration of treatment and safety. Probiotics and recombinant probiotic strain represent a promising source of molecules for the development of novel anti-infectious therapy.
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