Carbonic anhydrase IX inhibition is an effective strategy for osteosarcoma treatment

Hypoxia-induced carbonic anhydrase IX as a target for cancer therapy: From biology to clinical use

(2015) Jaromir Pastorek et al.   SEMINARS IN CANCER BIOLOGY

Recent Developments in Targeting Carbonic Anhydrase IX for Cancer Therapeutics

(2015) Paul C. McDonald et al.   Oncotarget

Immunohistochemical Reevaluation of Carbonic Anhydrase IX (CA IX) Expression in Tumors and Normal Tissues

(2014) Adelina Luong-Player et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Population Pharmacokinetics of Bevacizumab in Children with Osteosarcoma: Implications for Dosing

(2014) D. C. Turner et al.   CLINICAL CANCER RESEARCH

Targeting ion transport in cancer

(2014) E. Oosterwijk et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

HIF1α is an independent prognostic factor for overall survival in advanced primary epithelial ovarian cancer – a study of the OVCAD Consortium

(2014) Elena Braicu et al.   OncoTargets and Therapy

Carbonic anhydrase IX, a hypoxia-induced catalytic component of the pH regulating machinery in tumors

(2014) Olga Sedlakova   Frontiers in Physiology

Downregulation of MCT1 inhibits tumor growth, metastasis and enhances chemotherapeutic efficacy in osteosarcoma through regulation of the NF-κB pathway

(2013) Zhiqiang Zhao et al.   CANCER LETTERS

Tumor Cells Upregulate Normoxic HIF-1  in Response to Doxorubicin

(2013) Y. Cao et al.   CANCER RESEARCH

V-ATPase as an effective therapeutic target for sarcomas

(2013) Francesca Perut et al.   EXPERIMENTAL CELL RESEARCH

Proton pump inhibitor chemosensitization in human osteosarcoma: from the bench to the patients’ bed

(2013) Stefano Ferrari et al.   Journal of Translational Medicine

Hypoxia–Induced Cytotoxic Drug Resistance in Osteosarcoma Is Independent of HIF-1Alpha

(2013) Jennifer Adamski et al.   PLoS One

Additive Influence of Extracellular pH, Oxygen Tension, and Pressure on Invasiveness and Survival of Human Osteosarcoma Cells

(2013) Takao Matsubara et al.   Frontiers in Oncology

Long-term results (>25 years) of a randomized, prospective clinical trial evaluating chemotherapy in patients with high-grade, operable osteosarcoma

(2012) Nicholas M. Bernthal et al.   CANCER

Reciprocal Metabolic Reprogramming through Lactate Shuttle Coordinately Influences Tumor-Stroma Interplay

(2012) T. Fiaschi et al.   CANCER RESEARCH

Descriptive epidemiology of sarcomas in Europe: Report from the RARECARE project

(2012) C.A. Stiller et al.   EUROPEAN JOURNAL OF CANCER

Why is the partial oxygen pressure of human tissues a crucial parameter? Small molecules and hypoxia

(2011) Aude Carreau et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Functional characterization of osteosarcoma cell lines provides representative models to study the human disease

(2011) Alexander B Mohseny et al.   LABORATORY INVESTIGATION

Drug Resistance and Cellular Adaptation to Tumor Acidic pH Microenvironment

(2011) Jonathan W. Wojtkowiak et al.   MOLECULAR PHARMACEUTICS

Interfering with pH regulation in tumours as a therapeutic strategy

(2011) Dario Neri et al.   NATURE REVIEWS DRUG DISCOVERY

Carbonic anhydrase inhibitors. Inhibition studies of a coral secretory isoform by sulfonamides

(2009) Anthony Bertucci et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The relevance of a hypoxic tumour microenvironment in prostate cancer

(2009) Grant D. Stewart et al.   BJU INTERNATIONAL

Carbonic anhydrase IX in bladder cancer

(2009) Tobias Klatte et al.   CANCER

The Role of Carbonic Anhydrase 9 in Regulating Extracellular and Intracellular pH in Three-dimensional Tumor Cell Growths

(2009) Pawel Swietach et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Development of HIF-1 inhibitors for cancer therapy

(2009) Barbara Onnis et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Prediction Model of Chemotherapy Response in Osteosarcoma by 18F-FDG PET and MRI

(2009) G. J. Cheon et al.   JOURNAL OF NUCLEAR MEDICINE

Hypoxia Markers in Human Osteosarcoma: An Exploratory Study

(2008) Hiroo Mizobuchi et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

In vitro evaluation of freeze-dried bone allografts combined with platelet rich plasma and human bone marrow stromal cells for tissue engineering

(2008) Elisabetta Cenni et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

Alternative splicing variants of carbonic anhydrase IX in human non-small cell lung cancer

(2008) Francesca Malentacchi et al.   LUNG CANCER