The quest for targeted therapy in fragile X syndrome

Independent role for presynaptic FMRP revealed by anFMR1missense mutation associated with intellectual disability and seizures

(2015) Leila K. Myrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Fragile X syndrome neurobiology translates into rational therapy

(2014) Sien Braat et al.   DRUG DISCOVERY TODAY

Fragile X syndrome: From protein function to therapy

(2013) Claudia Bagni et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Epigenetics, fragile X syndrome and transcriptional therapy

(2013) Elisabetta Tabolacci et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

A Randomized Double-Blind, Placebo-Controlled Trial of Minocycline in Children and Adolescents with Fragile X Syndrome

(2013) Mary Jacena S. Leigh et al.   JOURNAL OF DEVELOPMENTAL AND BEHAVIORAL PEDIATRICS

FMRP Stalls Ribosomal Translocation on mRNAs Linked to Synaptic Function and Autism

(2011) Jennifer C. Darnell et al.   CELL

Epigenetic Modification of the FMR1 Gene in Fragile X Syndrome Is Associated with Differential Response to the mGluR5 Antagonist AFQ056

(2011) S. Jacquemont et al.   Science Translational Medicine

Open-label add-on treatment trial of minocycline in fragile X syndrome

(2010) Carlo Paribello et al.   BMC Neurology

Potential therapeutic interventions for fragile X syndrome

(2010) Josien Levenga et al.   TRENDS IN MOLECULAR MEDICINE