Characterization of a drug-targetable allosteric site regulating vascular endothelial growth factor signaling

Half-life extension using serum albumin-binding DARPin® domains

(2017) Daniel Steiner et al.   PROTEIN ENGINEERING DESIGN & SELECTION

Structure of the Full-length VEGFR-1 Extracellular Domain in Complex with VEGF-A

(2017) Sandra Markovic-Mueller et al.   STRUCTURE

Affimer proteins are versatile and renewable affinity reagents

(2017) Christian Tiede et al.   eLife

VEGFR-2 conformational switch in response to ligand binding

(2016) Sarvenaz Sarabipour et al.   eLife

Subcellular object quantification with Squassh3C and SquasshAnalyst

(2015) Aurélien Rizk et al.   BIOTECHNIQUES

Vascular endothelial growth factors: multitasking functionality in metabolism, health and disease

(2015) Gina A. Smith et al.   JOURNAL OF INHERITED METABOLIC DISEASE

VEGF-VEGFR Signals in Health and Disease

(2014) Masabumi Shibuya   Biomolecules & Therapeutics

The multifaceted activity of VEGF in angiogenesis – Implications for therapy responses

(2014) Stijn Moens et al.   CYTOKINE & GROWTH FACTOR REVIEWS

How good are my data and what is the resolution?

(2013) Philip R. Evans et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structural and mechanistic insights into VEGF receptor 3 ligand binding and activation

(2013) V.-M. Leppanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Anti-VEGF- and anti-VEGF receptor-induced vascular alteration in mouse healthy tissues

(2013) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

VEGFR and Type-V RTK Activation and Signaling

(2013) M. Shibuya   Cold Spring Harbor Perspectives in Biology

Targeting Extracellular Domains D4 and D7 of Vascular Endothelial Growth Factor Receptor 2 Reveals Allosteric Receptor Regulatory Sites

(2012) C. A. C. Hyde et al.   MOLECULAR AND CELLULAR BIOLOGY

Thermodynamic and structural description of allosterically regulated VEGFR-2 dimerization

(2011) M. S. Brozzo et al.   BLOOD

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Cell Signaling by Receptor Tyrosine Kinases

(2010) Mark A. Lemmon et al.   CELL

Structural Insights into the Binding of Vascular Endothelial Growth Factor-B by VEGFR-1D2

(2010) Shalini Iyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural determinants of growth factor binding and specificity by VEGF receptor 2

(2010) V.-M. Leppanen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct contacts between extracellular membrane-proximal domains are required for VEGF receptor activation and cell signaling

(2010) Y. Yang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Spheroid-based human endothelial cell microvessel formation in vivo

(2009) Anna M Laib et al.   Nature Protocols

Spheroid-based engineering of a human vasculature in mice

(2008) Abdullah Alajati et al.   NATURE METHODS

Stabilizing Ionic Interactions in a Full-consensus Ankyrin Repeat Protein

(2007) Tobias Merz et al.   JOURNAL OF MOLECULAR BIOLOGY