Selective IKK2 inhibitor IMD0354 disrupts NF-κB signaling to suppress corneal inflammation and angiogenesis

Genome-wide expression differences in anti-Vegf and dexamethasone treatment of inflammatory angiogenesis in the rat cornea

(2017) Pierfrancesco Mirabelli et al.   Scientific Reports

Ikk2 regulates cytokinesis during vertebrate development

(2017) Hongyuan Shen et al.   Scientific Reports

Ten years of anti-vascular endothelial growth factor therapy

(2016) Napoleone Ferrara et al.   NATURE REVIEWS DRUG DISCOVERY

Intrastromal Injection of Bevacizumab in the Management of Corneal Neovascularization: About 25 Eyes

(2016) Belghmaidi Sarah et al.   Journal of Ophthalmology

Differences in cardiovascular toxicities associated with cigarette smoking and snuff use revealed using novel zebrafish models

(2016) Maggie Folkesson et al.   Biology Open

A microarray whole-genome gene expression dataset in a rat model of inflammatory corneal angiogenesis

(2016) Anthony Mukwaya et al.   Scientific Data

Factors regulating capillary remodeling in a reversible model of inflammatory corneal angiogenesis

(2016) Anthony Mukwaya et al.   Scientific Reports

Panretinal Photocoagulation vs Intravitreous Ranibizumab for Proliferative Diabetic Retinopathy

(2015) et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

IKK  Regulates VEGF Expression and Is a Potential Therapeutic Target for Ovarian Cancer as an Antiangiogenic Treatment

(2015) Y. Kinose et al.   MOLECULAR CANCER THERAPEUTICS

VEGF-B-Neuropilin-1 signaling is spatiotemporally indispensable for vascular and neuronal development in zebrafish

(2015) Lasse D. Jensen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sex-specific regulation of chemokine Cxcl5/6 controls neutrophil recruitment and tissue injury in acute inflammatory states

(2015) Shimona Madalli et al.   Biology of Sex Differences

Early effects of dexamethasone and anti-VEGF therapy in an inflammatory corneal neovascularization model

(2014) Pierfrancesco Mirabelli et al.   EXPERIMENTAL EYE RESEARCH

CCL2 Shapes Macrophage Polarization by GM-CSF and M-CSF: Identification of CCL2/CCR2-Dependent Gene Expression Profile

(2014) E. Sierra-Filardi et al.   JOURNAL OF IMMUNOLOGY

CXCL5 is required for angiogenesis, but not structural adaptation after small bowel resection

(2014) Kathryn J. Rowland et al.   JOURNAL OF PEDIATRIC SURGERY

Carotenoids, inflammation, and oxidative stress—implications of cellular signaling pathways and relation to chronic disease prevention

(2014) Anouk Kaulmann et al.   NUTRITION RESEARCH

NF- B, the first quarter-century: remarkable progress and outstanding questions

(2012) M. S. Hayden et al.   GENES & DEVELOPMENT

Anti-VEGF Treatment of Corneal Neovascularization

(2012) Anne M. Keating et al.   Ocular Surface

Corneal Neovascularization and the Utility of Topical VEGF Inhibition: Ranibizumab (Lucentis) Vs Bevacizumab (Avastin)

(2012) William Stevenson et al.   Ocular Surface

Intravitreal Aflibercept (VEGF Trap-Eye) in Wet Age-related Macular Degeneration

(2012) Jeffrey S. Heier et al.   OPHTHALMOLOGY

Corneal Neovascularization: An Anti-VEGF Therapy Review

(2012) Jin-Hong Chang et al.   SURVEY OF OPHTHALMOLOGY

Opposing Effects of Circadian Clock Genes Bmal1 and Period2 in Regulation of VEGF-Dependent Angiogenesis in Developing Zebrafish

(2012) Lasse Dahl Jensen et al.   Cell Reports

Cellular level characterization of capillary regression in inflammatory angiogenesis using an in vivo corneal model

(2011) Beatrice Bourghardt Peebo et al.   ANGIOGENESIS

An IκB kinase 2 inhibitor IMD-0354 suppresses the survival of adult T-cell leukemia cells

(2011) Shin Uota et al.   CANCER SCIENCE

Anti-VEGF Therapy With Bevacizumab for Anterior Segment Eye Disease

(2011) Hamid Hosseini et al.   CORNEA

Freeze-gelled silk fibroin protein scaffolds for potential applications in soft tissue engineering

(2011) Nandana Bhardwaj et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Sphingosylphosphorylcholine Stimulates CCL2 Production from Human Umbilical Vein Endothelial Cells

(2011) Ha Young Lee et al.   JOURNAL OF IMMUNOLOGY

Use of the mouse aortic ring assay to study angiogenesis

(2011) Marianne Baker et al.   Nature Protocols

NF-κB in the liver—linking injury, fibrosis and hepatocellular carcinoma

(2011) Tom Luedde et al.   Nature Reviews Gastroenterology & Hepatology

IKKβ regulates essential functions of the vascular endothelium through kinase-dependent and -independent pathways

(2011) Noboru Ashida et al.   Nature Communications

Inflammation, but not hypoxia, mediated HIF-1α activation depends on COX-2

(2010) Ioannis Stasinopoulos et al.   CANCER BIOLOGY & THERAPY

The Chemokine Receptor CXCR2 Ligand KC (CXCL1) Mediates Neutrophil Recruitment and Is Critical for Development of Experimental Lyme Arthritis and Carditis

(2010) A. M. Ritzman et al.   INFECTION AND IMMUNITY

Topical Bevacizumab in the Treatment of Corneal Neovascularization

(2009) Mohammad H. Dastjerdi   ARCHIVES OF OPHTHALMOLOGY

Neutrophils promote inflammatory angiogenesis via release of preformed VEGF in an in vivo corneal model

(2009) Yue Gong et al.   CELL AND TISSUE RESEARCH

The NF- B Family of Transcription Factors and Its Regulation

(2009) A. Oeckinghaus et al.   Cold Spring Harbor Perspectives in Biology

The IKK Complex, a Central Regulator of NF- B Activation

(2009) A. Israel   Cold Spring Harbor Perspectives in Biology

The Nuclear Factor NF- B Pathway in Inflammation

(2009) T. Lawrence   Cold Spring Harbor Perspectives in Biology

NF-κB: a new player in angiostatic therapy

(2008) Sebastien P. Tabruyn et al.   ANGIOGENESIS

Regulation of hypoxia-inducible factor-1α by NF-κB

(2008) Patrick van Uden et al.   BIOCHEMICAL JOURNAL

Antiallergic and Anti-Inflammatory Effects of a Novel IκB Kinase β Inhibitor, IMD-0354, in a Mouse Model of Allergic Inflammation

(2008) Akemi Sugita et al.   INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY

NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α

(2008) Jordi Rius et al.   NATURE