An Artificial Heme Enzyme for Cyclopropanation Reactions

Highly Diastereo- and Enantioselective Synthesis of Trifluoromethyl-Substituted Cyclopropanes via Myoglobin-Catalyzed Transfer of Trifluoromethylcarbene

(2017) Antonio Tinoco et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Cyclopropanation by Myoglobin Reconstituted with Iron Porphycene: Acceleration of Catalysis due to Rapid Formation of the Carbene Species

(2017) Koji Oohora et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Design of an enantioselective artificial metallo-hydratase enzyme containing an unnatural metal-binding amino acid

(2017) Ivana Drienovská et al.   Chemical Science

Stereoselective Olefin Cyclopropanation under Aerobic Conditions with an Artificial Enzyme Incorporating an Iron-Chlorin e6 Cofactor

(2017) Gopeekrishnan Sreenilayam et al.   ACS Catalysis

Beyond Iron: Iridium-Containing P450 Enzymes for Selective Cyclopropanations of Structurally Diverse Alkenes

(2017) Hanna M. Key et al.   ACS Central Science

Myoglobin-Catalyzed Olefination of Aldehydes

(2016) Vikas Tyagi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mutating a Highly Conserved Residue in Diverse Cytochrome P450s Facilitates Diastereoselective Olefin Cyclopropanation

(2016) Joshua G. Gober et al.   CHEMBIOCHEM

Abiological catalysis by artificial haem proteins containing noble metals in place of iron

(2016) Hanna M. Key et al.   NATURE

Directed evolution of cytochrome c for carbon–silicon bond formation: Bringing silicon to life

(2016) S. B. Jennifer Kan et al.   SCIENCE

Myoglobin-catalyzed intermolecular carbene N–H insertion with arylamine substrates

(2015) Gopeekrishnan Sreenilayam et al.   CHEMICAL COMMUNICATIONS

From “hemoabzymes” to “hemozymes”: towards new biocatalysts for selective oxidations

(2015) J.-P. Mahy et al.   CHEMICAL COMMUNICATIONS

Chemomimetic Biocatalysis: Exploiting the Synthetic Potential of Cofactor-Dependent Enzymes To Create New Catalysts

(2015) Christopher K. Prier et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Supramolecular Assembly of Artificial Metalloenzymes Based on the Dimeric Protein LmrR as Promiscuous Scaffold

(2015) Jeffrey Bos et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Novel artificial metalloenzymes by in vivo incorporation of metal-binding unnatural amino acids

(2015) Ivana Drienovská et al.   Chemical Science

Highly Diastereoselective and Enantioselective Olefin Cyclopropanation Using Engineered Myoglobin-Based Catalysts

(2014) Melanie Bordeaux et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic multidrug recognition by multidrug transcriptional repressor LmrR

(2014) Koh Takeuchi et al.   Scientific Reports

Rational Heme Protein Design: All Roads Lead to Rome

(2013) Ying-Wu Lin et al.   Chemistry-An Asian Journal

A serine-substituted P450 catalyzes highly efficient carbene transfer to olefins in vivo

(2013) Pedro S Coelho et al.   Nature Chemical Biology

An enantioselective artificial metallo-hydratase

(2013) Jeffrey Bos et al.   Chemical Science

Cytochrome P450-catalyzed insertion of carbenoids into N–H bonds

(2013) Z. Jane Wang et al.   Chemical Science

Enantioselective Artificial Metalloenzymes by Creation of a Novel Active Site at the Protein Dimer Interface

(2012) Jeffrey Bos et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Olefin Cyclopropanation via Carbene Transfer Catalyzed by Engineered Cytochrome P450 Enzymes

(2012) P. S. Coelho et al.   SCIENCE

Asymmetric Inter- and Intramolecular Cyclopropanation Reactions Catalyzed by a Reusable Macroporous-Polymer-Supported Chiral Ruthenium(II)/Phenyloxazoline Complex

(2010) Abdel-Moneim Abu-Elfotoh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

De Novo Design and Molecular Assembly of a Transmembrane Diporphyrin-Binding Protein Complex

(2010) Ivan V. Korendovych et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Speciation of Ferriprotoporphyrin IX in Aqueous and Mixed Aqueous Solution Is Controlled by Solvent Identity, pH, and Salt Concentration

(2009) Constance Asher et al.   INORGANIC CHEMISTRY

Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition

(2008) Pramod Kumar Madoori et al.   EMBO JOURNAL