期刊
ANALYTICAL METHODS
卷 10, 期 27, 页码 3347-3352出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c8ay01288a
关键词
-
资金
- Brazilian funding agency CNPq [303902/2015-9]
- Brazilian funding agency CAPES
- Brazilian funding agency Fundacao Araucaria do Parana
A boron-doped diamond electrode (BDDE) was employed for indapamide hydrochloride (IND) determination. IND presented an irreversible and diffusion-controlled oxidation peak at 0.53 V in 0.01 mol L-1 H2SO4 by cyclic voltammetry. To develop the voltammetric method, the effect of electrochemical pretreatment of BDDE, pH of supporting electrolyte, type of electrolyte and its concentration were evaluated. Under optimized instrumental parameters of square-wave voltammetry, the IND current was linear over the concentration range of 0.099-4.3 mol L-1, with limit of detection of 56 nmol L-1. The method was successfully applied to commercial tablets, and the obtained results were statistically similar to those obtained by a spectrophotometric method. Additionally, the determination of IND was accomplished in synthetic cerebrospinal fluid and tap water. The method proved to not suffer from matrix interference with excellent recoveries.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据