Aptamers: current challenges and future prospects

The Ups and Downs of Clinical Translation of New Technologies: Déjà Vu All Over Again

(2015) Paul A Burke   MOLECULAR THERAPY

Generation of Aptamers with an Expanded Chemical Repertoire

(2015) Stella Diafa et al.   MOLECULES

Predicting the Uncertain Future of Aptamer-Based Diagnostics and Therapeutics

(2015) John Bruno   MOLECULES

Large scale analysis of the mutational landscape in HT-SELEX improves aptamer discovery

(2015) Jan Hoinka et al.   NUCLEIC ACIDS RESEARCH

Facilitating aptamer selection and collection by capillary transient isotachophoresis with laser-induced fluorescence detection

(2014) Kathryn R. Riley et al.   JOURNAL OF CHROMATOGRAPHY A

Is less more? Lessons from aptamer selection strategies

(2014) Zsuzsanna Szeitner et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

By-Product Formation in Repetitive PCR Amplification of DNA Libraries during SELEX

(2014) Fabian Tolle et al.   PLoS One

Quantitative selection and parallel characterization of aptamers

(2013) M. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of RNA aptamers that internalize into HPV-16 E6/E7 transformed tonsillar epithelial cells

(2013) Francoise A. Gourronc et al.   VIROLOGY

Progress in Ion Torrent semiconductor chip based sequencing

(2012) Barry Merriman et al.   ELECTROPHORESIS

A Logic-Gated Nanorobot for Targeted Transport of Molecular Payloads

(2012) S. M. Douglas et al.   SCIENCE

Synthetic Genetic Polymers Capable of Heredity and Evolution

(2012) V. B. Pinheiro et al.   SCIENCE

Current Progress of RNA Aptamer-Based Therapeutics

(2012) Jiehua Zhou et al.   Frontiers in Genetics

Improving Aptamer Selection Efficiency through Volume Dilution, Magnetic Concentration, and Continuous Washing in Microfluidic Channels

(2011) Seung Soo Oh et al.   ANALYTICAL CHEMISTRY

Immobilization-free screening of aptamers assisted by graphene oxide

(2011) Jee-Woong Park et al.   CHEMICAL COMMUNICATIONS

Nucleic Acid Aptamers: Clinical Applications and Promising New Horizons

(2011) X. Ni et al.   CURRENT MEDICINAL CHEMISTRY

Isolation of DNA aptamers using micro free flow electrophoresis

(2011) Meng Jing et al.   LAB ON A CHIP

Assembly of multifunctional phi29 pRNA nanoparticles for specific delivery of siRNA and other therapeutics to targeted cells

(2011) Yi Shu et al.   METHODS

Dual functional RNA nanoparticles containing phi29 motor pRNA and anti-gp120 aptamer for cell-type specific delivery and HIV-1 Inhibition

(2011) Jiehua Zhou et al.   METHODS

Aptamer-Based Multiplexed Proteomic Technology for Biomarker Discovery

(2011) Larry Gold et al.   PLoS One

Emulsion PCR: A High Efficient Way of PCR Amplification of Random DNA Libraries in Aptamer Selection

(2011) Keke Shao et al.   PLoS One

Probing the SELEX Process with Next-Generation Sequencing

(2011) Tatjana Schütze et al.   PLoS One

Where Are All the Aptamers?

(2010) Geoffrey S. Baird   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Antibody validation

(2010) Jennifer Bordeaux et al.   BIOTECHNIQUES

Automation in the High-throughput Selection of Random Combinatorial Libraries—Different Approaches for Select Applications

(2010) Jörn Glökler et al.   MOLECULES

Quantitative selection of DNA aptamers through microfluidic selection and high-throughput sequencing

(2010) M. Cho et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Use of a Multiplexed CMOS Microarray to Optimize and Compare Oligonucleotide Binding to DNA Probes Synthesized or Immobilized on Individual Electrodes

(2010) Karl Maurer et al.   SENSORS

Generation of Highly Specific Aptamers via Micromagnetic Selection

(2009) Jiangrong Qian et al.   ANALYTICAL CHEMISTRY

Polymerase engineering: towards the encoded synthesis of unnatural biopolymers

(2009) David Loakes et al.   CHEMICAL COMMUNICATIONS

Systemic administration of optimized aptamer-siRNA chimeras promotes regression of PSMA-expressing tumors

(2009) Justin P Dassie et al.   NATURE BIOTECHNOLOGY

Development of universal antidotes to control aptamer activity

(2009) Sabah Oney et al.   NATURE MEDICINE

In silico selection of RNA aptamers

(2009) Y. Chushak et al.   NUCLEIC ACIDS RESEARCH

Micromagnetic selection of aptamers in microfluidic channels

(2009) X. Lou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overview of Electrochemical DNA Biosensors: New Approaches to Detect the Expression of Life

(2009) Stefano Cagnin et al.   SENSORS

The new paradigm of flow cell sequencing

(2008) R. A. Holt et al.   GENOME RESEARCH

Novel Dual Inhibitory Function Aptamer–siRNA Delivery System for HIV-1 Therapy

(2008) Jiehua Zhou et al.   MOLECULAR THERAPY

Next-generation DNA sequencing

(2008) Jay Shendure et al.   NATURE BIOTECHNOLOGY