Article
Biochemistry & Molecular Biology
Lidia Magerusan, Florina Pogacean, Stela Pruneanu
Summary: Due to the safety concerns associated with acetaminophen, a quick and environmentally friendly method using direct voltage application in saltwater has been developed to synthesize nitrogen-doped graphene (exf-NGr). The exf-NGr-modified electrode shows excellent performance in acetaminophen detection and quantification, with good reproducibility and stability, as well as wide detection range capabilities.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Physical
Naveen Karuppusamy, Vinitha Mariyappan, Shen Ming Chen, Mohan Das Thangamuthu, Ru-Han Li
Summary: It is crucial to monitor the level of AAP in the human body and consumption sources to prevent severe health issues caused by overdose and prolonged use of acetaminophen drugs. In this study, a manganese cobalt phosphide (MnCo-P) modified electrode on sulfur-doped reduced graphene oxide (S-RGO) composite was developed for electrochemical detection of AAP. The results showed high sensitivity and low detection limit of the MnCo-P/S-RGO electrode, making it significant for AAP level monitor in clinical settings.
SURFACES AND INTERFACES
(2023)
Article
Chemistry, Inorganic & Nuclear
Chuanqin Zhou, Shuting Shi, Yanping Wei, Aiting Chen, Nana Tang, Jingsong Zuo, Quanguo He, Peihong Deng
Summary: In this study, hollow tubular manganese-cobalt sulfide (MnS/Co3S4) hybrids were synthesized and anchored on graphene oxide (GO) using a hydrothermal method and ultrasonic dispersion. The resulting nanocomposites were drop-coated onto a glassy carbon electrode (GCE) to construct a sensitive sensor for acetaminophen (AC) detection. The electrochemical performance of the MnS/Co3S4-ERGO/GCE was evaluated, showing excellent electrocatalytic activity for AC oxidation. The method demonstrated high accuracy for AC determination in commercial tablets and human serum samples, with satisfactory recoveries.
INORGANIC CHEMISTRY COMMUNICATIONS
(2023)
Article
Chemistry, Physical
Shujun Wang, Fengping Chen, Zhi Li, Huan Tao, Liangzhuo Qu, Jinhua Li, Mingshan Zhu, Qingbing Zha
Summary: In this study, an electrochemical sensor based on a graphene oxide (GO)/Zn-metal organic framework (ZIF-8) composite electrode was developed for the detection of acetaminophen (APAP). The sensor exhibited higher sensitivity and improved electrochemical performance compared to pure ZIF-8 due to the introduction of GO, which enhanced the electron transport capacity of ZIF-8. It showed excellent selectivity, repeatability, and was successfully applied for the determination of APAP in human urine samples and drug tablets.
SURFACES AND INTERFACES
(2023)
Article
Electrochemistry
Jianzhi Huang, Zhixin Qiu, Hao Yang, Chujun Chen, Yanliang Li
Summary: A unique peak potential position reversal phenomenon was observed on a black phosphorus nanosheets electrochemical sensor, which significantly improved the detection selectivity for simultaneous determination of isoniazid and acetaminophen. The sensor successfully achieved simultaneous determination of the two compounds in low concentration range, with wide linear detection range and low detection limits, and was applied in real clinical samples for early prevention of liver failure disease.
ELECTROCHIMICA ACTA
(2022)
Article
Chemistry, Analytical
Mostafa Poursoltani Zarandi, Hadi Beitollahi
Summary: A sensitive and high-performance electrochemical sensing method was designed to detect 4-aminophenol, and simultaneously detect acetaminophen, showing great potential for various applications.
MICROCHEMICAL JOURNAL
(2022)
Article
Chemistry, Physical
Ramasamy Santhosh Kumar, Kadarkarai Govindan, Shanmugam Ramakrishnan, Ae Rhan Kim, Jong-Soo Kim, Dong Jin Yoo
Summary: The increase in world population has led to a greater need for solutions to health and environmental issues. The development of Fe3O4@PPy/rGO nanohybrids has shown promising results in electrochemical detection of dopamine and photodegradation of acetaminophen. The study provides a new direction for the use of metal oxide conducting polymer and graphene-based catalysts in multifunctional applications.
APPLIED SURFACE SCIENCE
(2021)
Article
Chemistry, Analytical
Liangliang Huang, Haiyan Chen, Dongfeng Diao
Summary: In this study, an electrochemical etching method was used to manufacture high-density graphene edges on the surface of N-doped graphene sheets embedded carbon films for sensing aminophenol. The etched film exhibited better electrochemical activity and can simultaneously detect 4-aminophenol and acetaminophen.
ANALYTICA CHIMICA ACTA
(2022)
Article
Materials Science, Ceramics
Sajjad Hussain, Imran Sadiq, Jameel Ahmed Baig, Farhan Sadiq, Muhammad Shahbaz, Imam Bakhsh Solangi, Mishal Idrees, Samreen Saeed, Saira Riaz, Shahzad Naseem
Summary: This study synthesized spinel vanadium nano-ferrite (VFe2O4) for the electrochemical sensing of acetaminophen (Ac) and characterized its structural, magnetic, and electrochemical properties. The results confirmed the cubic single-phase spinel crystalline structure of VFe2O4 and its excellent superparamagnetic properties. The VFe2O4 coated on the glassy carbon electrode (GCE) surface showed modification for the electrocatalytic oxidative sensing of Ac. The proposed VFe2O4/GCE exhibited high selectivity and was successfully used for quantitative routine sensing of Ac in biological fluids and pharmaceutical samples.
CERAMICS INTERNATIONAL
(2023)
Article
Materials Science, Biomaterials
Velu Duraisamy, Velayutham Sudha, Venkataraman Dharuman, Sakkarapalayam Murugesan Senthil Kumar
Summary: In this study, hollow mesoporous carbon sphere-based materials of cobalt oxide and heteroatom-doped materials were investigated for sensor applications. A highly homogeneous Co3O4-embedded N-doped hollow carbon sphere (Co3O4@NHCS) was successfully synthesized by a one-step polymerization method using dopamine hydrochloride and cobalt phthalocyanine precursors. The resulting Co3O4@NHCS materials exhibited excellent electrochemical performance for the sensing of acetaminophen, with a linear range, sensitivity, and limit of detection that are suitable for practical applications.
ACS BIOMATERIALS SCIENCE & ENGINEERING
(2023)
Article
Chemistry, Inorganic & Nuclear
Yanan Li, Jiqi Zheng, Jiaze Yan, Yanyan Liu, Ming Guo, Yifu Zhang, Changgong Meng
Summary: In this study, an effective electrochemical sensor was developed for rapid and sensitive determination of DPA, a harmful pesticide used to control post-harvest scald of fruits. The sensor was fabricated by coupling La-doped NiWO4 nanoparticles with reduced graphene oxide and exhibited enhanced electrocatalytic performance. It showed a wide linear range, low detection limit, and high sensitivity. The sensor was successfully applied to DPA detection in fresh apple extract with excellent recoveries.
DALTON TRANSACTIONS
(2023)
Article
Environmental Sciences
Saisai Chen, Ming Zhang, Hao Zhang, Xin Yan, Jia Xie, Junwen Qi, Xiuyun Sun, Jiansheng Li
Summary: The dicyandiamide-assisted strategy successfully synthesized well-dispersed Cu/N-doped porous carbon nanoarchitecture with significantly improved electrochemical detection performance for acetaminophen. The enhanced performance can be attributed to the evenly distributed small Cu nanoparticles, abundant N species, hierarchical channel structure, and high conductivity carbon framework.
ENVIRONMENTAL RESEARCH
(2021)
Article
Chemistry, Analytical
Yujie Li, Xiaoli Liu, Jianbin Zheng
Summary: A dual-ratiometric electrochemical sensor based on a methylene blue/Cu/N-doped porous carbon composite was fabricated for the determination of acetaminophen. The Cu/N-C acted as an internal reference and provided attachment sites for methylene blue, allowing for the linear detection of acetaminophen in the range of 0.5 to 150.0 μM.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Baojun Long, Yuanmeng Zhao, Peiyu Cao, Wen Wei, Yan Mo, Juejing Liu, Cheng-Jun Sun, Xiaofeng Guo, Changsheng Shan, Ming-Hua Zeng
Summary: The researchers designed a catalyst composed of single-atom Pt supported on Ni(OH)(2) nanoplates/nitrogen-doped graphene for constructing an electrochemical nonenzymatic glucose sensor. The catalyst exhibited low anode peak potential and high sensitivity, with excellent selectivity, short response time, and high stability. The improved performance of the catalyst was attributed to the stronger binding strength of glucose on the single-atom Pt active centers and their surrounding Ni atoms, as well as the fast electron transfer ability of the conductive graphene.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Yan-mei Shi, Xi Zhang, Lin Mei, De-en Han, Kai Hu, Li-Qin Chao, Xiu-min Li, Ming-san Miao
Summary: A new amplified signal strategy for acetaminophen electrochemical sensor was developed using a soluble zinc tetrahydroxyphthalocyanine-reduced graphene oxide nanocomposite as an improved electrode material. The sensor showed a sensitive and selective electroanalytical method for AC, with linear response in different concentration ranges and excellent selectivity, reproducibility, and long-term stability.
MICROCHEMICAL JOURNAL
(2021)
Article
Nanoscience & Nanotechnology
Yunyue Lu, Heli Song, Xin Li, Hans Agren, Qingyun Liu, Jiwei Zhang, Xuan Zhang, Yongshu Xie
ACS APPLIED MATERIALS & INTERFACES
(2019)
Article
Spectroscopy
Zhen-Ni Lu, Lei Wang, Xuan Zhang, Zhi-Jia Zhu
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2019)
Article
Chemistry, Inorganic & Nuclear
Qi Zhang, Xuan Zhang
SOLID STATE SCIENCES
(2019)
Article
Chemistry, Multidisciplinary
Xuan Zhang, Li Zhang, Wei-Wei Ma, Yong Zhou, Zhen-Ni Lu, Suying Xu
FRONTIERS IN CHEMISTRY
(2019)
Article
Chemistry, Physical
Li Zhang, Lei Wang, Xuan Zhang, Zhi-Jia Zhu
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2020)
Article
Materials Science, Multidisciplinary
Ji-Wei Zhang, Kai-Ping Wang, Xuan Zhang
MATERIALS RESEARCH BULLETIN
(2020)
Article
Spectroscopy
Lei Wang, Xuan-Yu Zheng, Xuan Zhang, Zhi-Jia Zhu
Summary: A novel quinoline-benzimidazole conjugate was designed for highly selective fluorescent detection of Pd2+ over other metal cations, showing good linear relationship and low detection limit. Successful fluorescence detection of Pd2+ in practical water samples was achieved.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2021)
Article
Chemistry, Analytical
Kai-Ping Wang, Jian-Mei Hu, Xuan Zhang
Summary: The novel electrochemical sensor constructed on a glassy carbon electrode coated with iodine-doped graphene showed good linear response and low detection limit for bisphenol A. It demonstrated high selectivity, good stability, excellent reproducibility, and successful application in detecting BPA in real milk samples.
MICROCHEMICAL JOURNAL
(2022)
Article
Nanoscience & Nanotechnology
Lai-Wei Jia, Xuan Zhang
Summary: Red-emissive carbon dots (RCDs) with triplet fluorescence emission were synthesized from o-phenylenediamine and catechol through a hydrothermal method in ethanol. The RCDs were used to create bright and stable fluorescent patterns on cotton fabrics and to construct reversible volatile acid/amineresponsive RCD-patterned smart textiles and paper indicators. Additionally, fluorescence-sensing platforms were developed for MnO4- using an inner-filter-effect approach, allowing for the quantitative detection of MnO4- in aqueous solution and practical water sample analysis with satisfactory recovery results.
ACS APPLIED NANO MATERIALS
(2023)
Article
Chemistry, Analytical
Lei Wang, Wan-Yu Zhu, Xuan Zhang
Summary: A novel quinoline-based fluorescent chemosensor (QB-3) was designed for the detection of Pd2+ in pure water. QB-3 exhibited a selective and fast fluorescence quenching response to Pd2+ without interference from other metal ions. The stoichiometry between QB-3 and Pd2+ was found to be 2:1, and the fluorescence quenching mechanism may be attributed to electron transfer.
CHINESE JOURNAL OF ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Physical
Ji-Wei Zhang, Xuan Zhang
JOURNAL OF ALLOYS AND COMPOUNDS
(2020)
Article
Multidisciplinary Sciences
Kai-Ping Wang, Yi-Chi Zhang, Xuan Zhang, Li Shen
SN APPLIED SCIENCES
(2019)
Article
Materials Science, Biomaterials
Yong Zhou, Li Zhang, Xuan Zhang, Zhi-Jia Zhu
JOURNAL OF MATERIALS CHEMISTRY B
(2019)
Article
Materials Science, Paper & Wood
Kai Liu, Xuan Zhang, Kelu Yan
Article
Chemistry, Analytical
Yujia Ying, Huilin Li
Summary: Enzymes play a crucial role as biological catalysts in accelerating biochemical reactions in living organisms. This study proposes a convenient method for monitoring enzymatic catalytic processes using native top-down mass spectrometry. By exploring the heterogeneity of the chymotrypsin sample and using tandem mass spectrometry, the researchers were able to monitor covalent and noncovalent enzymatic complexes, substrates, and products during catalysis. The results demonstrate that this method has the potential to be a promising tool for characterizing biocatalysts.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Kang Yang, Shuaibo Shi, Jinyu Wu, Shaolong Han, Shengdi Tai, Shishen Zhang, Kun Zhang
Summary: H2O and D2O are important analogues closely related to various industries and monitoring fields. This study successfully distinguishes and detects H2O and D2O by designing a novel eu(III)-macrocycle with dual emitters, Eu-2a, and conducting fluorescence titration experiments.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Julia Kuligowski, Alvaro Perez-Rubio, Marta Moreno-Torres, Polina Soluyanova, Judith Perez-Rojas, Ivan Rienda, David Perez-Guaita, Eugenia Pareja, Ramon Trullenque-Juan, Jose Castell, Marcha Verheijen, Florian Caiment, Ramiro Jover, Guillermo Quintas
Summary: This study introduces a novel variable selection approach called cluster PLS (c-PLS) to assess the joint impact of variable groups selected based on biological characteristics on the predictive performance of a multivariate model. The usefulness of c-PLS is shown using miRNomic and metabolomic datasets obtained from the analysis of liver tissue biopsies.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Meixue Lai, Lijie Zhong, Siyi Liu, Yitian Tang, Tingting Han, Huali Deng, Yu Bao, Yingming Ma, Wei Wang, Li Niu, Shiyu Gan
Summary: This study presents a method for constructing wearable sweat electrolyte sensors using carbon fiber-based solid-contact ion-selective electrodes (SC-ISEs). By using carbon fibers extracted from commercial cloth as electrode material, the cost and reproducibility issues of flexible SC-ISEs were addressed. The results showed that the carbon fiber-based SC-ISEs exhibited reversible voltammetric and stable impedance performances, and had high reproducibility of standard potentials between normal and bending states.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Yang, Ying Liu, Min Deng, Peipei Wang, Dan Cheng, Songjiao Li, Longwei He
Summary: A near-infrared fluorescent probe has been developed to accurately measure the levels of peroxynitrite (ONOO-) in the endoplasmic reticulum (ER) in acute lung injury (ALI). The probe demonstrated rapid response, high selectivity, good sensitivity, and enhanced fluorescence intensity in response to ONOO-. It was successfully used to detect changes in ONOO- levels and showed significant increases in an ALI cell model and an ALI mouse model.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yanping Wang, Yuemei Chen, Kejun Li, Jinrong Zhou, Xin Yuan, Mei Zhang, Ke Huang
Summary: In this work, a portable analytical system based on point discharge chemical vapor generation atomic emission spectrometry (PD-CVG-AES) coupling with gold filament enrichment was designed. The highly sensitive analysis of Hg2+ indirectly realized the detection of ascorbic acid (AA). The measurement is based on the fact that Ag+ can decrease the concentration of Hg2+ by forming Ag-Hg amalgam in the presence of the reductant SnCl2, while AA can pre-reduce Ag+ to Ag0, leading to the generation of silver nanoparticles (Ag NPs). The developed novel analytical strategy broadens the application of microplasma-based AES and offers a higher level of sensitivity compared to current AA detection techniques.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yundi Huang, Bo Song, Kaiwen Chen, Deshu Kong, Jingli Yuan
Summary: This study developed two lysosome-targetable background-free TGL probes for efficient and accurate detection of 1O2, which can be used for monitoring endogenous 1O2 concentrations in lysosomes and discriminating variability induced by different photosensitizers. Furthermore, a smart luminescent sensor film was successfully prepared for on-site 1O2 production detection during PDT processes, offering a promising clinical monitoring tool for skin diseases.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Wei Lang, Jia-Mei Qin, Qian-Yong Cao
Summary: A novel polymer-based probe P1 was successfully synthesized for fluorescently ratiometric sensing of H2S with high selectivity and sensitivity. A smartphone sensing platform was constructed to conduct visual quantitative detection of H2S. P1 can be employed in evaluating the level fluctuations of H2S in living cells, testing water samples/wine samples, and monitoring food freshness.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Yuanyuan Qin, Shuda Liu, Shuyun Meng, Dong Liu, Tianyan You
Summary: The study developed a split aptamer-based sandwich-type ratiometric biosensor for the detection of 17 beta-estradiol (E2) using photoelectrochemical and electrochemical assays. The biosensor utilized split aptamer fragments to recognize E2 and trigger a hybridization chain reaction, resulting in the production of double-stranded DNA labeled with CdTe quantum dots. This DNA complex was able to sensitize CdTe quantum dots and generate response signals for E2 detection. The developed biosensor demonstrated high sensitivity and accuracy with two linear ranges and low detection limits.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Siriwan Teepoo, Jongjit Jantra, Khaunnapa Panapong, David Taiwo Ajayi
Summary: A novel immunochromatographic assay based on hyperbranched Au plasmonic blackbodies with a smartphone readout was developed for rapid and sensitive detection of leucomalachite green residues in fish and shrimp products.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Andrea L. Larraga-Urdaz, Borja Moreira-Alvarez, Jorge Ruiz Encinar, Jose M. Costa-Fernandez, Maria Luisa Fernandez-Sanchez
Summary: A major challenge in the 21st century is the development of point-of-care diagnostic tools. In this study, a highly sensitive and simple bioassay using AuNPs and MNAzymes was developed for rapid detection and quantification of miRNA-4739. The proposed strategy shows potential for breast cancer diagnosis.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Xiaohan Zhao, Anyu Wang, Lingzi Zhai, Jiuhe Gao, Sizhe Lyu, Yingshan Jiang, Tian Zhong, Ying Xiao, Xi Yu
Summary: A novel method using polystyrene-coated magnetic nanoparticles for extracting monohydroxy polycyclic aromatic hydrocarbons from urine samples was investigated. The proposed method is simple, sensitive, and efficient, with desirable sensitivity for analyzing low-abundance metabolites in large volumes of complex urine samples.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Ke Quan, Yuqing Zeng, Wenke Zhang, Fengfeng Li, Mengjiao Li, Zhihe Qing, Linlin Wu
Summary: In this study, a visual and reusable biosensor was developed for detecting substrates that are closely associated with human physiological health. The immobilized oxidase showed higher stability and sensitivity under harsh conditions, enabling reliable detection of substrates in complex fluids.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Dongjuan Wang, Xiuqian Ding, Jinling Xie, Juan Wang, Guanhao Li, Xin Zhou
Summary: In this study, a three-in-one sensor was developed for real-time detection of biogenic amines (BAs) with high sensitivity and selectivity. The sensor showed multimodal responses and could be used to fabricate portable devices for on-site non-destructive assessment of food spoilage indicators.
ANALYTICA CHIMICA ACTA
(2024)
Article
Chemistry, Analytical
Jinting Meng, Zihao Xu, Shasha Zheng, Hongqun Yang, Tianfu Wang, Hong Wang, Yingwei Zhang
Summary: This study demonstrates the development of a cascade signal amplification system using a multi-pedal DNA walker and strand displacement reactions for the electrochemical detection of miRNA-155. The biosensor exhibited high sensitivity, selectivity, and the potential for clinical applications.
ANALYTICA CHIMICA ACTA
(2024)
