Article
Biophysics
Zhuoxin Ye, Yibing Liu, Meichen Pan, Xiuli Tao, Yuxuan Chen, Pinyi Ma, Ying Zhuo, Daqian Song
Summary: In this study, low-toxic quaternary AgInZnS quantum dots were synthesized and used as novel anodic electrochemiluminescence (ECL) emitters. These QDs exhibited strong and stable ECL emission, a low excitation potential, and high ECL efficiency. An on-off-on ECL biosensor for detecting microRNA-141 was designed based on a dual isothermal enzyme-free strand displacement reaction, achieving cyclic amplification of the target and ECL signal, as well as a switch function. The ECL biosensor showed a wide linear range and low detection limit, making it a promising tool for rapid and accurate diagnosis of clinical diseases.
BIOSENSORS & BIOELECTRONICS
(2023)
Review
Chemistry, Analytical
Hui Sun, Ping Zhou, Bin Su
Summary: Electrochemiluminescence (ECL) is chemiluminescence that is triggered by electrochemical reactions. ECL has become a powerful analytical technique widely used in biosensing and imaging due to its unique excitation mode and low background. Semiconductor quantum dots (QDs), as emerging ECL luminophores, have significant advantages over traditional molecular luminophores in terms of luminescence efficiency and signal modulation ability. Therefore, the development of an efficient ECL system using QDs as luminophores is important for improving the sensitivity and detection flux of ECL biosensors.
Article
Chemistry, Analytical
Yu-Ting Yang, Jia-Li Liu, Man-Fei Sun, Ruo Yuan, Ya-Qin Chai
Summary: A novel electrochemiluminescence biosensor based on MnS:CdS@ZnS QDs was developed for ultrasensitive detection of miRNA let-7a. The biosensor exhibited high stability and excellent sensitivity, with a detection limit as low as 4.1 aM.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Jingjing Jiang, Xuezhong Du
Summary: The label-free ratiometric electrochemiluminescence (ECL) sensing strategy proposed in this study utilizes G-quadruplex/hemin-regulated ECL emissions of CdS quantum dots and luminol as the coreactant for the sensitive detection of target DNA. The ECL biosensor shows a wide response range for T-DNA detection, low detection limit, and excellent selectivity against mismatched base sequences, providing a reliable and sensitive sensing platform for the detection of targets in the analytical community.
Article
Chemistry, Analytical
Yu Lin, Jiawen Wu, Yeyu Wu, Rongxian Ma, Yuyi Zhou, Jinyue Shi, Mingxiang Li, Xuecai Tan, Kejing Huang
Summary: An electrochemiluminescence (ECL) biosensor is constructed for ultrasensitive determination of miRNA-21. The biosensor utilizes AuNPs/GDY, GDYO QDs, and an oligonucleotide signal amplification strategy that integrates DNA walker and hybridization chain reaction (HCR) amplification. The biosensor demonstrates outstanding performance in the detection of miRNA-21 in the linear range from 0.1 fM to 1 nM, offering a new sensitive method for the clinical analysis of cancer biomarkers.
Article
Chemistry, Analytical
Zuhao Zhang, Lu Zhang, Shujing Wang, Ruifang Liu, Li Li, Peini Zhao, Chaomin Gao, Fengming Chen, Shenguang Ge, Jinghua Yu
Summary: A CRISPR/Cas12a electrochemiluminescence biosensor was developed for ultrasensitive detection of miRNA-21. The biosensor utilized Tribulus terrestris-like AuCu nanoterrestris and DNA tetrahedral nanostructures, and employed a multiple sites DNA walker for signal amplification, achieving efficient detection.
SENSORS AND ACTUATORS B-CHEMICAL
(2023)
Article
Chemistry, Analytical
Gui Zhang, Qian Han, Li Song, Pingkun Liu, Guangrong Kuang, Yingzi Fu
Summary: The enthusiasm for green chemistry among chemists has increased, leading to the synthesis of plant leaf-derived carbon dots and oxidized carbon dots. The oxidized maple CDP showed promising results as a green source luminophore and was used for the ultrasensitive detection of miRNA-21. This work provides a new opportunity for synthesizing green source luminophores and detecting various trace miRNA species.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Analytical
Shuangtian Dong, Dongyang Wang, Xuwen Gao, Li Fu, Jingna Jia, Yuqi Xu, Bin Zhang, Guizheng Zou
Summary: This study proposes a method to achieve chemiluminescence with different wavelengths and intensities by adjusting triggering agents, which shows promising potential for applications in immunoassays and other fields.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Xiang Hu, Ying Wang, Xiong Zuping, Pei Song, Ai-Jun Wang, Zhaosheng Qian, Pei-Xin Yuan, Tiejun Zhao, Jiu-Ju Feng
Summary: In this study, an aggregation-enhanced PEC photosensitizer PPIX-[BMIm] was prepared by electrostatic bonding, and its PEC performance in a binary solvent of water and DMSO was studied. A label-free PEC cytosensor was built using PPIX-[BMIm], which showed a wide linear range and low limit of detection for detecting leukemia cells.
ANALYTICAL CHEMISTRY
(2022)
Article
Engineering, Environmental
Linlei Liu, Yuanqi Xu, Yidan Zhu, Haijun Wang, Yaqin Chai, Ruo Yuan
Summary: In this study, carbon nitride quantum dots (CNQDs) with efficient near-infrared electrochemiluminescence (NIR-ECL) and excellent biocompatibility were prepared as an emitter to construct an ultrasensitive regenerative biosensing platform for detection of microRNA-222 (miRNA-222). The introduction of electron-rich pyrimidine effectively increased the conjugation effect of electrons on triazine ring in CNQDs, resulting in red shift of ECL emission wavelength. An improved circular DNA walker was assembled by the catalytic ligation of T4 DNA ligase to enhance its stability and walking efficiency. By utilizing CNQDs as emitter and circular DNA walker as signal amplifier, a regenerative biosensor platform was developed for ultrasensitive detection of miRNA-222 with high sensitivity and successfully applied for detection in cancer cells lysate. This work opens up a promising approach for synthesizing efficient NIR-ECL CNQDs, reducing damage to organisms and achieving deeper tissue penetration, and provides a new method for biomarker detection and disease diagnosis.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Chemistry, Analytical
Yang Yang, Jia-Ling Zhang, Wen-Bin Liang, Jin-Ling Zhang, Xiao-Li Xu, Yong-Jiang Zhang, Ruo Yuan, Dong-Rong Xiao
Summary: A conductive bimetallic MOF nanorod (NiCo-HHTP) with excellent electrical conductivity and ECL performance was synthesized using a doping strategy, which could be utilized for constructing ultrasensitive ECL biosensors.
SENSORS AND ACTUATORS B-CHEMICAL
(2022)
Review
Biotechnology & Applied Microbiology
Hong Ruan, Li Zhou
Summary: The rapid industrialization has caused serious environmental problems and increased disease and healthcare issues. The development of simple and effective biosensors is crucial for disease prevention and treatment. Sulfur quantum dots, as a new fluorescent nanomaterial, offer great potential in the fields of bioimaging and biosensing.
FRONTIERS IN BIOENGINEERING AND BIOTECHNOLOGY
(2022)
Article
Engineering, Environmental
Qian Han, Cun Wang, Pingkun Liu, Gui Zhang, Li Song, Yingzi Fu
Summary: The study demonstrates the excellent performance and stability of three types of porphyrin dots in electrochemiluminescence, with significantly higher ECL efficiency in the S2O82- cathodic system compared to the standard. Additionally, a biosensor utilizing these porphyrin dots shows ultrasensitive detection of Pb2+.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Chemistry, Analytical
Ali Firoozbakhtian, Morteza Hosseini, Mahsa Naghavi Sheikholeslami, Foad Salehnia, Guobao Xu, Hodjattallah Rabbani, Ebtesam Sobhanie
Summary: The rapid spread of SARS-CoV-2 has raised the need for efficient and rapid diagnostic tools. In this study, an electrochemiluminescence (ECL)-based detection system was developed and trained using machine learning algorithms to accurately diagnose COVID-19 with over 90% accuracy. The system provides a cost-effective and time-saving alternative to traditional testing methods.
ANALYTICAL CHEMISTRY
(2022)
Article
Chemistry, Analytical
Li Wang, Wei-Jia Zeng, Xia Yang, Ruo Yuan, Wen-Bin Liang, Ying Zhuo
Summary: In this work, luminescent groups rich carbon dots (Lu-CDs) were synthesized by incorporating luminol into the CDs, resulting in a significantly enhanced electrochemiluminescent (ECL) performance. The ECL emission of Lu-CDs showed excellent consistency with its fluorescence emission, unlike other surface state-dominated CDs. Furthermore, Lu-CDs were used to develop an ECL biosensor for tumor cell analysis, demonstrating a wide detection range and low detection limit.
ANALYTICAL CHEMISTRY
(2023)
Review
Chemistry, Multidisciplinary
Yu-Ling Wang, Jun-Tao Cao, Yan-Ming Liu
Summary: This article introduces the principles, classifications, and applications of bipolar electrochemistry (BPE) at micro/nanoscale, and discusses its importance in areas such as electrocatalysis, electrosynthesis, and electrophoresis.
Article
Nanoscience & Nanotechnology
Chan Yang, Yarong Hu, Sanxiu Li, Qun Huang, Juan Peng
Summary: In this study, self-supporting bimetallic nanoleaves consisting of Bi and Sb components were fabricated on carbon paper using a facile electrodeposition method. The synergistic effect of Bi and Sb and the change of electronic structure led to high formate selectivity and excellent stability in the electrochemical CO2 reduction reaction. Furthermore, the bimetallic Bi-Sb catalyst exhibited outstanding stability for formate generation in flow cells, which is rarely reported in previous studies. This work offers new insights into the development of bimetallic self-supporting electrodes for CO2 reduction.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Physical
Xueping Yu, Beibei Gao, Biao Feng, Yage Peng, Xiaoyong Jin, Gang Ni, Juan Peng, Min Yao
Summary: Modular electrochemical production (MEP) system can separate the production of hydrogen and oxygen by using a redox mediator (RM). In this study, a Mott-Schottky Co9S8/Ni3S2 heterojunction was constructed as a RM to achieve the separation of hydrogen and oxygen in space and time in the MEP system. The MEP system involved a two-step electro-chemical-electrochemical (EC-EC) looping process, where the Co9S8/Ni3S2 redox reaction was paired with the hydrogen evolution reaction (HER) in step 1 and the oxygen evolution reaction (OER) in step 2. The Co9S8/Ni3S2 RM showed high area capacitance and stability, and the MEP system had high energy efficiency and could be powered by renewable solar energy.
INTERNATIONAL JOURNAL OF HYDROGEN ENERGY
(2023)
Article
Biochemistry & Molecular Biology
Sanxiu Li, Yufei Kang, Chenyang Mo, Yage Peng, Haijun Ma, Juan Peng
Summary: This study provides a valuable strategy to enhance the catalytic performance of bismuth-based catalysts for CO2RR by using a nitrogen-doping strategy.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2022)
Article
Chemistry, Multidisciplinary
Litao Jia, Pei Yu, Ying Dong, Yonglei Xing, Juan Peng, Gang Ni, Xiaoyong Jin
Summary: The selection of superior photoanode semiconductors with excellent photoelectrocatalytic efficiency is a challenge in the application of PEC oxidation technology. In this study, a novel S-Co3O4/Bi2WO6 heterojunction photoanode was fabricated and exhibited a large electroactive surface area, low charge transfer resistance, strong light absorption ability, and high separation efficiency for electron/hole pairs. The S-Co3O4/Bi2WO6 photoanode played a dominant role in the degradation of tetracycline and showed better PEC performance than other materials.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Inorganic & Nuclear
Senda Su, Xiaoman Li, Mengyao Tan, Xu Zhang, Yingying Wang, Yanzhong Duan, Juan Peng, Min Luo
Summary: This study reveals the influence of different interlayer anions on the photocatalytic performance of ZnAl-LDHs, providing a new approach to enhance the catalytic activity of LDHs in the photocatalytic nitrogen fixation reaction.
INORGANIC CHEMISTRY FRONTIERS
(2023)
Article
Nanoscience & Nanotechnology
Chen Chen, Yu-Ling Wang, Xiao Lin, Shu-Hui Ma, Jun-Tao Cao, Yan-Ming Liu
Summary: A closed bipolar electrochemiluminescence (BP-ECL) platform was developed for sensitive prostate specific antigen (PSA) detection using a novel synergistic signal amplification strategy. Cu-based metal-organic frameworks loaded with glucose oxidase (Cu-MOFs/GOx) were used as bifunctional probes, bridged on the anodic interface with the target PSA. The strategy enabled the generation of gluconic acid, which degraded Cu-MOFs to release Cu2+ and accelerate the formation of highly active intermediates, leading to enhanced ECL intensity.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Nanoscience & Nanotechnology
Hui-Jin Xiao, Yu-Ling Wang, Cheng-Jun Liu, Zi-Hui Gao, Shu-Wei Ren, Jun-Tao Cao, Yan-Ming Liu
Summary: A self-powered photoelectrochemical biosensing system for protein detection was proposed based on a liposome-assisted signal amplification strategy. The system utilized Ag nanoparticle-encapsulated liposomes to generate signal regulator Ag+ for photoelectrochemical detection. By forming Ag3PO4/AgBr/Br-CN ternary heterostructures, the system broadened the light absorption range and reduced electron-hole recombination, resulting in enhanced photocurrent response. The biosensing system exhibited high sensitivity for protein detection.
ACS APPLIED NANO MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Rui Yang, Qun Huang, Xuelan Sha, Beibei Gao, Juan Peng
Summary: By constructing bimetallic metal organic frameworks (MOFs) materials, the catalytic performance of the electrocatalyst for CO2 conversion to formate was optimized. BiZn-MOF exhibited higher catalytic activity and formate selectivity. The study reveals the potential of tuning the electronic structure and atomic arrangement to improve catalytic performance.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Sanxiu Li, Xuelan Sha, Xiafei Gao, Juan Peng
Summary: This paper synthesized Al-doped octahedral Cu2O (Al-Cu2O) nanocrystals by a simple wet chemical method. The selectivity of CO2RR products was improved by doping Al onto the surface of octahedral Cu2O. The Al-Cu2O was used as an efficient electrocatalyst for CO2RR with selective ethylene production.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Xiafei Gao, Mengyue Gao, Xueping Yu, Xiaoyong Jin, Gang Ni, Juan Peng
Summary: By using the Al-Co2Fe(CN)6/NF electrode, efficient urea oxidation reaction and water splitting can be achieved under alkaline conditions. The electrode exhibits excellent catalytic activity and long-term stability, and significantly saves energy in the entire urea electrolysis system.
Article
Chemistry, Multidisciplinary
Yu-Ling Wang, Yi-Zhuo Fu, Hui-Jin Xiao, Pan Wu, Shu-Wei Ren, Jun-Tao Cao, Yan-Ming Liu
Summary: An off-on-type electrochemiluminescence (ECL) system for Myoglobin (Myo) assay was developed using black-phosphorus nanosheets (BP NSs) and MnO2 nanosheets (MnO2 NSs) as nanocomposites. The system utilized resonance energy transfer (RET) and functional liposomes as probes. The ECL signal was regulated by glutathione (GSH) released from liposomes, allowing for the estimation of Myo concentration. The ECL system demonstrated a good linear relationship for Myo detection in human serum samples.
NEW JOURNAL OF CHEMISTRY
(2023)
Article
Chemistry, Physical
Jianpeng Yang, Shihu Du, Bangmin Ju, Ziheng Zhang, Gang Li, Jinghan Zou, Juntao Cao, Qiangshan Jing, Hua Xie, Ling Jiang
Summary: The reactions between carbon monoxide and nickel carbide were studied using spectroscopic techniques, and the products were characterized and analyzed using quantum chemical calculations. Efficient C-C bond formation process was revealed in this reaction, highlighting the significant roles played by metal carbides in C-C bond formation.
JOURNAL OF PHYSICAL CHEMISTRY A
(2023)
Article
Chemistry, Multidisciplinary
Xueping Yu, Li Qu, Carmen Lee, Juan Peng, Qingyu Yan, Hongcun Bai, Min Yao
Summary: In this study, a mesoporous Bi-Ni bimetal nanosheet was prepared by a self-template electrochemical in situ process as an electrocatalyst, and it exhibited similar activity and stability to commercial Pt/C for efficient hydrogen generation through water electrolysis.
Article
Chemistry, Physical
Wenfei Dong, Nan Zhang, Sanxiu Li, Shixiong Min, Juan Peng, Wanyi Liu, Dongping Zhan, Hongcun Bai
Summary: The electrocatalytic reduction of CO2 using electricity produced from renewable resources is an effective strategy for reducing CO2 emissions and promoting sustainable energy development. This study successfully synthesized a low Mn-content single-atom catalyst with efficient electrocatalytic performance for the CO2 reduction reaction.
JOURNAL OF MATERIALS CHEMISTRY A
(2022)
