Article
Pediatrics
Stella Li, Tonia Douglas, Dominic A. Fitzgerald
Summary: This review summarizes the experiences of young children and their families living with CF during the first five years of life following NBS diagnosis, as well as the options of psychosocial support available to them. We present strategies embedded within routine CF care that focus on prevention, screening, and intervention for psychosocial health and wellbeing that constitute essential components of multidisciplinary care in infancy and early childhood.
PAEDIATRIC RESPIRATORY REVIEWS
(2023)
Article
Ophthalmology
Justine R. Smith, Janet M. Matthews, Diana Conrad, Anthony J. Hall, Rachael L. Niederer, Davinder Singh-Grewal, Mei-Ling Tay-Kearney, Jane M. Wells, Sophia L. Zagora, Peter J. McCluskey
Summary: The Australian and New Zealand-based uveitis-specialized ophthalmologists have developed 18 consensus statements for managing chronic anterior uveitis in children with JIA, providing regionally applicable advice for ophthalmic care.
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Ophthalmology
Justine Huard, Sorina-Dana Mihailescu, Marc Muraine, Solen Raymond, Martine Grall Lerosey, Julie Gueudry
Summary: This study analyzed the effectiveness and safety of weekly adalimumab dosing in children with non-infectious refractory chronic anterior uveitis (CAU). The results showed that weekly adalimumab was an effective and safe treatment for controlling inflammation and reducing the need for corticosteroids in children with CAU.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Pediatrics
Pawan Kumar, Anju Gupta, Reema Bansal, Deepti Suri, Vishali Gupta, Amod Gupta, Surjit Singh
Summary: The study found that 43% of patients with chronic uveitis had no identifiable cause, juvenile idiopathic arthritis was the most common known cause, patients required prolonged use of oral glucocorticoids and other immunosuppressants to control inflammation, and there was a high rate of ocular complications among the patients.
INDIAN JOURNAL OF PEDIATRICS
(2022)
Article
Ophthalmology
Virginia Miraldi Utz, Sheila T. Angeles-Han, Najima Mwase, Amy Cassedy, Theresa Hennard, Daniel J. Lovell, Sarah Lopper, Hermine Brunner, Eniolami O. Dosunmu, Alexei A. Grom, Michael Henrickson, Jennifer L. Huggins, Robert A. Sisk, Tracy V. Ting, Adam H. Kaufman
Summary: In this study, alternative biologics (abatacept, golimumab, and tocilizumab) were found to be effective in treating CAU in children who did not respond to MTX and cTNFi therapy. Patients who were successfully treated with ABT had higher disease activity, ocular complications, and anti-cTNFi neutralizing antibodies compared to those on conventional therapy.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Rheumatology
Rianne Elise van Bentum, Frank D. Verbraak, Sanne Wolf, Jenny Ongkosuwito, Maarten Boers, H. Stevie Tan, Irene E. van der Horst-Bruinsma
Summary: This observational study evaluated the prevalence of previously unrecognized axial spondyloarthritis (axSpA) in patients with acute anterior uveitis (AAU) referred by ophthalmologists due to concurrent chronic back pain (CBP). The study found a high prevalence of axSpA in these patients, with a significant diagnostic delay in the majority of patients with recurring AAU. Screening for CBP and prompt referral in AAU has a high diagnostic yield and should be promoted among ophthalmologists.
JOURNAL OF RHEUMATOLOGY
(2022)
Article
Multidisciplinary Sciences
Courtney J. Pedersen, Mohammad J. Uddin, Samir K. Saha, Gary L. Darmstadt
Summary: Severe atopic dermatitis significantly impacts the quality of life for children and families in Bangladesh. The severity of acute symptoms is positively correlated with quality of life index, and the severity rated by caregivers is also correlated with quality of life and family index.
Article
Multidisciplinary Sciences
Rafael Salom, Luis Miguel Aras, Jessica Pinero, Jon Andoni Dunabeitia
Summary: Caring for children with DEE is challenging for primary caregivers, impacting their quality of life and support network. Quantitative data is needed to address their needs. A database was developed using CRESIA to measure the psychosocial impact and assess caregivers' well-being.
Review
Nutrition & Dietetics
Lyndsey Hookway, Jan Lewis, Amy Brown
Summary: Breastfeeding medically complex children presents practical and psychological challenges, such as difficulties continuing breastfeeding in a hospital setting, complications of the condition, lack of specialist support from hospital staff, and unavailable specialist equipment. This highlights the need for further research and consistent high-quality care for lactation support in pediatric settings.
MATERNAL AND CHILD NUTRITION
(2021)
Article
Nursing
Ghada Mohammad Abu Shosha, Mahmoud Al-Kalaldeh, Noordeen Shoqirat
Summary: Jordanian nurses value the importance of providing psychosocial care for children with thalassaemia, but face barriers such as a lack of specialists and screening tools. Training programmes and adjustments to nursing curricula are recommended to improve nurses' ability to provide effective psychosocial care.
Article
Ophthalmology
Carlyn V. Kouwenberg, Roos A. W. Wennink, Mahfam Shahabi, Irem Bozkir, Viera Koopman-kalinina Ayuso, Joke H. De Boer
Summary: This study aimed to compare the clinical course and outcome of children with idiopathic chronic anterior uveitis (iCAU) and children with juvenile idiopathic arthritis-associated uveitis (JIA-U). The results showed that children with iCAU had a higher prevalence of ocular complications compared to children with JIA-U, and younger children with iCAU were more likely to develop posterior synechiae, secondary glaucoma, and require cataract surgery.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2022)
Article
Medicine, General & Internal
Charlotte L. L. I. van Meerwijk, Astrid B. Edema, Laurentius J. van Rijn, Leonoor I. Los, Nomdo M. Jansonius
Summary: This study retrospectively evaluated the efficacy and safety of goniotomy for pediatric non-infectious uveitis, and found that it effectively reduced intraocular pressure, had a low rate of complications and re-interventions, and achieved a high success rate.
JOURNAL OF CLINICAL MEDICINE
(2023)
Article
Psychology, Developmental
Angela Tseng
Summary: This study is the first to examine the effects of Autism-Assistance Dogs (AADs) on children with autism and their families using validated clinical, behavioral, and physiological measures. The results demonstrate significant positive psychosocial and biobehavioral effects of AADs.
JOURNAL OF AUTISM AND DEVELOPMENTAL DISORDERS
(2023)
Article
Nursing
Helga Jonsdottir, Bryndis S. Halldorsdottir, Thorbjorg Soley Ingadottir
Summary: This study revised the partnership-based nursing practice framework for people with COPD, highlighting the importance of dialogue and action between nurses, patients, and their families. The revised framework has the potential to enhance the lives of COPD patients and their families, especially in advanced stages of the disease. It may also have applicability to other progressive diseases and complex health problems to reduce healthcare resource usage.
JOURNAL OF ADVANCED NURSING
(2023)
Article
Psychiatry
Carla Kotze, Gopolang Zwide
Summary: Advancements in psychiatric genetics have highlighted the importance of genetic counseling in clinical practice, particularly for patients with schizophrenia. Genetic counseling plays a crucial role in helping individuals and their families make informed decisions regarding genetic testing and mitigating unrealistic expectations and stigma.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Ophthalmology
Sheila T. Angeles-Han, Virginia Miraldi Utz, Sherry Thornton, Grant Schulert, Jackeline Rodriguez-Smith, Adam Kauffman, Alyssa Sproles, Najima Mwase, Theresa Hennard, Alexei Grom, Mekibib Altaye, Gary N. Holland
Summary: In this study, inflammatory biomarkers in tears were successfully detected in children with JIA-U, with IL-8, sICAM-1, and S100A12 identified as potential biomarkers for uveitis activity.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2021)
Article
Rheumatology
Margaret H. Chang, Jessica G. Shantha, Jacob J. Fondriest, Mindy S. Lo, Sheila T. Angeles-Han
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA
(2021)
Article
Rheumatology
Karen B. Onel, Daniel B. Horton, Daniel J. Lovell, Susan Shenoi, Carlos A. Cuello, Sheila T. Angeles-Han, Mara L. Becker, Randy Q. Cron, Brian M. Feldman, Polly J. Ferguson, Harry Gewanter, Jaime Guzman, Yukiko Kimura, Tzielan Lee, Katherine Murphy, Peter A. Nigrovic, Michael J. Ombrello, C. Egla Rabinovich, Melissa Tesher, Marinka Twilt, Marisa Klein-Gitelman, Fatima Barbar-Smiley, Ashley M. Cooper, Barbara Edelheit, Miriah Gillispie-Taylor, Kimberly Hays, Melissa L. Mannion, Rosemary Peterson, Elaine Flanagan, Nadine Saad, Nancy Sullivan, Ann Marie Szymanski, Rebecca Trachtman, Marat Turgunbaev, Keila Veiga, Amy S. Turner, James T. Reston
Summary: This study provides recommendations for the management of juvenile idiopathic arthritis, focusing on nonpharmacologic therapies, medication monitoring, immunizations, and imaging. The guideline emphasizes the importance of improving patient quality of life and involving patients and caregivers in decision-making. However, the evidence quality for all recommendations is low.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Rheumatology
Karen B. Onel, Daniel B. Horton, Daniel J. Lovell, Susan Shenoi, Carlos A. Cuello, Sheila T. Angeles-Han, Mara L. Becker, Randy Q. Cron, Brian M. Feldman, Polly J. Ferguson, Harry Gewanter, Jaime Guzman, Yukiko Kimura, Tzielan Lee, Katherine Murphy, Peter A. Nigrovic, Michael J. Ombrello, C. Egla Rabinovich, Melissa Tesher, Marinka Twilt, Marisa Klein-Gitelman, Fatima Barbar-Smiley, Ashley M. Cooper, Barbara Edelheit, Miriah Gillispie-Taylor, Kimberly Hays, Melissa L. Mannion, Rosemary Peterson, Elaine Flanagan, Nadine Saad, Nancy Sullivan, Ann Marie Szymanski, Rebecca Trachtman, Marat Turgunbaev, Keila Veiga, Amy S. Turner, James T. Reston
Summary: This study provides updated guidelines for pharmacologic management of juvenile idiopathic arthritis (JIA), focusing on specific types of JIA and treatment options. The recommendations are based on low-quality evidence and are conditional in nature.
ARTHRITIS CARE & RESEARCH
(2022)
Article
Rheumatology
Karen B. Onel, Daniel B. Horton, Daniel J. Lovell, Susan Shenoi, Carlos A. Cuello, Sheila T. Angeles-Han, Mara L. Becker, Randy Q. Cron, Brian M. Feldman, Polly J. Ferguson, Harry Gewanter, Jaime Guzman, Yukiko Kimura, Tzielan Lee, Katherine Murphy, Peter A. Nigrovic, Michael J. Ombrello, C. Egla Rabinovich, Melissa Tesher, Marinka Twilt, Marisa Klein-Gitelman, Fatima Barbar-Smiley, Ashley M. Cooper, Barbara Edelheit, Miriah Gillispie-Taylor, Kimberly Hays, Melissa L. Mannion, Rosemary Peterson, Elaine Flanagan, Nadine Saad, Nancy Sullivan, Ann Marie Szymanski, Rebecca Trachtman, Marat Turgunbaev, Keila Veiga, Amy S. Turner, James T. Reston
Summary: This guideline provides recommendations for the management of juvenile idiopathic arthritis, focusing on nonpharmacologic therapies, medication monitoring, immunizations, and imaging. Recommendations include physical therapy and occupational therapy interventions, a healthy diet, medication monitoring, immunizations, and shared decision-making with patients/caregivers.
ARTHRITIS & RHEUMATOLOGY
(2022)
Article
Rheumatology
Karen B. Onel, Daniel B. Horton, Daniel J. Lovell, Susan Shenoi, Carlos A. Cuello, Sheila T. Angeles-Han, Mara L. Becker, Randy Q. Cron, Brian M. Feldman, Polly J. Ferguson, Harry Gewanter, Jaime Guzman, Yukiko Kimura, Tzielan Lee, Katherine Murphy, Peter A. Nigrovic, Michael J. Ombrello, C. Egla Rabinovich, Melissa Tesher, Marinka Twilt, Marisa Klein-Gitelman, Fatima Barbar-Smiley, Ashley M. Cooper, Barbara Edelheit, Miriah Gillispie-Taylor, Kimberly Hays, Melissa L. Mannion, Rosemary Peterson, Elaine Flanagan, Nadine Saad, Nancy Sullivan, Ann Marie Szymanski, Rebecca Trachtman, Marat Turgunbaev, Keila Veiga, Amy S. Turner, James T. Reston
Summary: This article provides updated guidelines for the pharmacologic management of juvenile idiopathic arthritis (JIA), focusing on different forms of JIA and providing recommendations for treatment and tapering of medications. The evidence for these recommendations is generally low quality, but the inclusion of patients and caregivers in the decision-making process strengthens the relevance and applicability of the guideline.
ARTHRITIS & RHEUMATOLOGY
(2022)
Letter
Rheumatology
Courtney McCracken, Jessica G. Shantha, Steven Yeh, Kirsten Jenkins, Kelly A. Rouster-Stevens, Scott R. Lambert, Sampath Prahalad, Carolyn Drews-Botsch, Sheila T. Angeles-Han
JOURNAL OF RHEUMATOLOGY
(2022)
Editorial Material
Rheumatology
Sheila T. Angeles-Han, Sunil K. Srivastava
JOURNAL OF RHEUMATOLOGY
(2023)
Review
Immunology
Ilaria Maccora, Edoardo Marrani, Ilaria Pagnini, Maria Vincenza Mastrolia, Cinzia de Libero, Roberto Caputo, Gabriele Simonini
Summary: Childhood uveitis is a serious condition that can lead to blindness if not properly recognized and treated. This review discusses the main causes, diagnostic approach, risk factors, and difficulties in eye examination for childhood uveitis. The treatment options for childhood uveitis are also discussed in terms of choice, timing, and withdrawal.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
(2023)
Editorial Material
Immunology
Ilaria Maccora, Preston Land, Virginia Miraldi Utz, Sheila T. Angeles-Han
EXPERT REVIEW OF CLINICAL IMMUNOLOGY
(2023)
Meeting Abstract
Ophthalmology
Dominick Canady, Caleb Hartley, Amy Cassedy, Chris Miller, Sheila T. Angeles-Han, Matthew Jusu Vandy, Gilberte Bastien, Natalie Weil, Steven Yeh, Jessica Shantha
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Meeting Abstract
Ophthalmology
Jacob Fondriest, Amy Cassedy, Theresa Hennard, Carolyn Drews-Botsch, Jessi Lipscomb, Courtney McCracken, Joseph McDonald, Sampath Prahalad, Jessica Shantha, Virginia Utz, Steven Yeh, Sheila T. Angeles-Han
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Article
Rheumatology
Daniel J. Lovell, Bin Huang, Chen Chen, Sheila T. Angeles-Han, Teresa A. Simon, Hermine Brunner
Summary: This study compared the prevalence of multiple coexisting autoimmune diseases in patients with juvenile idiopathic arthritis (JIA) and a general paediatric (GP) patient population. Results showed that JIA patients had a higher prevalence of a large number of coexisting autoimmune diseases compared to the GP population, with 53.8% of the evaluated conditions having significantly higher prevalence in the JIA cohort.
Meeting Abstract
Rheumatology
Jackeline Rodriguez-Smith, Virginia Miraldi Utz, Amy Cassedy, Sherry Thornton, Grant Schulert, Alyssa Sproles, Najima Mwase, Theresa Hennard, Mekibib Altaye, Alexei Grom, Sheila Angeles-Han
ARTHRITIS & RHEUMATOLOGY
(2020)
Meeting Abstract
Rheumatology
Ivan Foeldvari, Jens Klotsche, Sheila Angeles-Han, Jordi Anton, Gabriele Simonini, Nadine Groesch, Jean Baer
ARTHRITIS & RHEUMATOLOGY
(2020)
Editorial Material
Ophthalmology
David Cui, Ian J. Saldanha, Gavin Li, Priya M. Mathews, Michael X. Lin, Esen K. Akpek
Summary: This article reports on the heterogeneity in methodology of clinical trials submitted to the US Food and Drug Administration for approval of topical dry eye treatments. Multiple outcome measures were used in these trials, highlighting the need for standardized assessment tools to optimize the evaluation and comparison of therapeutic benefits.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Adanna Udeh, Dana Huh, Terri Young, O'rese Knight, Fasika Woreta
Summary: This study examines the rates and trends of faculty promotions within the field of ophthalmology, with a focus on the rates of promotion among underrepresented in medicine (URiM) faculty. The results show that Black faculty had lower promotion rates and were more likely to leave academic medicine, highlighting the need for strategies and policies to address equity in promotion rates and retention of URiM faculty in academic ophthalmology.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Ursula Greferath, Erica Fletcher, Judy Savige, Heather G. Mack
Summary: Retinal drusen are uncommon in IgA nephropathy, but they resemble drusen found in age-related macular degeneration. The IgA-staining deposits in the drusen are likely related to systemic deposition of IgA. The nature of cystic spaces in the drusen is still unknown. Further research on the retinas of people with glomerulonephritis is recommended.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Andrew Mihalache, Ryan S. Huang, Nikhil S. Patil, Marko M. Popovic, Ashwin Mallipatna, Peter J. Kertes, Rajeev H. Muni, Radha P. Kohly
Summary: This study examines sociodemographic predictors of poor vision in children and adolescents in the US. The findings suggest that factors such as affordability of medical care, public health insurance, age, and parental education level are associated with vision difficulty. Addressing these disparities through public health policies is crucial for achieving equity in vision health.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Johannes Birtel, Richard Caswell, Samantha R. De Silva, Philipp Herrmann, Salwah Rehman, Andrew J. Lotery, Omar A. Mahroo, Michel Michaelides, Andrew R. Webster, Robert E. Maclaren, Peter Charbel Issa
Summary: The study investigated the phenotype, variability, and penetrance of IMPG2-related maculopathy. The results showed that mono-allelic IMPG2 variants could result in haploinsufficiency manifesting as a maculopathy with variable penetrance and expressivity. Family members of patients with IMPG2-related retinitis pigmentosa may also present with vitelliform lesions. The maculopathy is usually limited to the fovea and is associated with moderate visual impairment.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Colas Nils Authie, Mylene Poujade, Alireza Talebi, Alexis Defer, Ariel Zenouda, Cecilia Coen, Saddek Mohand-Said, Philippe Chaumet-Riffaud, Isabelle Audo, Jose-Alain Sahel
Summary: MOST has been validated as a reliable mobility test for measuring the movement ability of patients with vision impairments in both real and virtual environments.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Maria Krisch, Jordan Ueberroth, Neha Gupta, Stephen Merriam, Mark p. Breazzano
Summary: Orbeez-related ocular trauma can lead to severe visual morbidity and various intraocular sequelae. Adolescents may be at higher risk for posterior segment complications. Elevated IOP and hyphema at initial presentation may indicate a need for more aggressive interventions.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Jaron Pruett, Kelly Ruland, Sean Donahue
Summary: The study aimed to validate or refute the hypothesis that infants with birthweight over 750 g and gestational age over 27 weeks, who did not have retinopathy of prematurity (ROP) at 37 weeks, would not develop treatable ROP. The findings of the study supported the termination of examination at 37 weeks in infants meeting these criteria, as the value of continued screening was minimal.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Emily Sun, Jing Tian, Loaah Eltemsah, Divya Srikumaran, Grace Sun, Jessica Chow, Fasika Woreta
Summary: This study aims to evaluate the research productivity of ophthalmology residency applicants and identify differences in productivity based on gender and race. The findings reveal that women have similar or higher research outputs compared to men, while self-identified underrepresented in medicine (URiM) students have lower research outputs in ophthalmology. Therefore, greater mentorship and support for URiM students are needed to promote the recruitment of diverse trainees in ophthalmology programs.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)
Article
Ophthalmology
Isaac A. Bernstein, Ann Caroline Fisher, Kuldev Singh, Sophia Y. Wang
Summary: This study aims to investigate the association between visual field loss and frailty in a nationally representative cohort of US adults.
AMERICAN JOURNAL OF OPHTHALMOLOGY
(2024)