Article
Oncology
Sebastien Gendarme, Jean-Claude Pairon, Pascal Andujar, Francois Laurent, Patrick Brochard, Fleur Delva, Benedicte Clin, Antoine Gislard, Christophe Paris, Isabelle Thaon, Helene Goussault, Florence Canoui-Poitrine, Christos Chouaid
Summary: This study analyzed the cost-effectiveness ratio of implementing a lung cancer screening program for asbestos-exposed population. The results show that biennial screening for smokers with high asbestos exposure is cost-effective.
Article
Public, Environmental & Occupational Health
Dirk Taeger, Katharina Wichert, Martin Lehnert, Swaantje Casjens, Beate Pesch, Daniel G. Weber, Thomas Bruening, Georg Johnen, Thomas Behrens
Summary: This study aimed to estimate the lung cancer and mesothelioma incidence risk in men with benign asbestos-related lung or pleural diseases. The results showed a significant association between pleural plaques and increased risk for mesothelioma, while no significant association was found for lung cancer.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Benedicte Clin, Celine Gramond, Isabelle Thaon, Patrick Brochard, Fleur Delva, Soizick Chammings, Antoine Gislard, Francois Laurent, Christophe Paris, Aude Lacourt, Jean-Claude Pairon
Summary: This study analyzed the incidence and mortality of head and neck cancers in a French cohort of workers previously exposed to asbestos, and found a significant relationship between asbestos exposure and head and neck cancers, excluding laryngeal cancers. The presence of pleural plaques did not significantly affect this relationship.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Hee-Soon Juon, Alicia Hong, Marcella Pimpinelli, Madhuwani Rojulpote, Russell McIntire, Julie A. Barta
Summary: The study examined the relationship between occupational exposures and lung cancer diagnosis, finding that African-Americans had higher odds of lung cancer diagnosis than White individuals, especially when exposed to asbestos and silica. Effective public health prevention programs are needed, particularly for minorities who may face disproportionately greater occupational exposures due to socioeconomic constructs and barriers.
PREVENTIVE MEDICINE
(2021)
Article
Respiratory System
Fraser J. H. Brims, Edward J. A. Harris, Conor Murray, Chellan Kumarasamy, Alice Ho, Brendan Adler, Peter Franklin, Nick H. de Klerk
Summary: This study analyzed the effectiveness of LDCT screening for early lung cancer in an asbestos exposed population and compared different screening program eligibility criteria. The results showed that LDCT screening was effective at identifying early-stage lung cancer in this population, and the existing lung cancer risk criteria did not adequately capture this population.
Article
Oncology
Keith Sigel, Rafael E. de la Hoz, Steven B. Markowitz, Chung Yin Kong, Kimberly Stone, Andrew C. Todd, Juan P. Wisnivesky
Summary: This study investigates the impact of toxic inhalable particles exposure on lung cancer risk among World Trade Center (WTC) rescue and recovery workers. The results suggest that there is no significant elevation in lung cancer incidence among WTC RRWV compared to an unexposed cohort. Age, smoking intensity, and mineral dust work are found to be associated with lung cancer risk.
Article
Oncology
Pietro Gino Barbieri, Dario Consonni, Anna Somigliana
Summary: The study found no significant relationship between asbestos lung burden and survival, with histologic subtype being the strongest prognostic determinant.
JOURNAL OF THORACIC ONCOLOGY
(2022)
Article
Respiratory System
Reimar Wernich Thomsen, Anders Hammerich Riis, Esben Meulengracht Flachs, David H. Garabrant, Jens Peter Ellekilde Bonde, Henrik Toft Sorensen
Summary: Acetylene welding is a common arc welding method that uses an oxygen-acetylene flame to heat and melt the welding pieces, with a flame temperature of about 3,200°C (5,800°F), suitable for welding various metals.
Article
Public, Environmental & Occupational Health
Justine Gallet, Francois Laurent, Christophe Paris, Benedicte Clin, Antoine Gislard, Isabelle Thaon, Soizick Chammings, Celine Gramond, Guy Ogier, Gilbert Ferretti, Pascal Andujar, Patrick Brochard, Fleur Delva, Jean-Claude Pairon, Aude Lacourt
Summary: This study aimed to evaluate the association between occupational asbestos exposure and lung cancer with pleural plaques (PP). The results showed a significant association between PP and lung cancer incidence and mortality, particularly in non-smokers.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2022)
Article
Cardiac & Cardiovascular Systems
Dong D. Wang, Yanping Li, Shilpa N. Bhupathiraju, Bernard A. Rosner, Qi Sun, Edward L. Giovannucci, Eric B. Rimm, JoAnn E. Manson, Walter C. Willett, Meir J. Stampfer, Frank B. Hu
Summary: The study found that consuming approximately 5 servings of fruits and vegetables per day was associated with lower total mortality and mortality from cancer, cardiovascular disease, and respiratory disease. Higher intake beyond this level did not provide additional risk reduction.
Article
Oncology
Zhaoqiang Jiang, Junqiang Chen, Junfei Chen, Lingfang Feng, Mingying Jin, Huixian Zhong, Li Ju, Lijin Zhu, Yun Xiao, Zhenyu Jia, Chengmin Xu, Difang Yu, Xing Zhang, Jianlin Lou
Summary: Female workers in the asbestos processing industry in Eastern China face a high risk of developing multiple types of cancer, particularly respiratory diseases and lung cancer. This study suggests that asbestos exposure is associated with excess mortality from these diseases.
FRONTIERS IN ONCOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Karen Walker-Bone, Geza Benke, Ewan MacFarlane, S. Klebe, Ken Takahashi, Fraser Brims, Malcolm Ross Sim, Tim R. Driscoll
Summary: Mesothelioma, a rare and deadly cancer associated with asbestos exposure, continues to be diagnosed in Australia despite the ban on asbestos since 2003. The Australian Mesothelioma Registry was established to gather comprehensive data on incidence, mortality, and asbestos exposure. Results show a decline in incidence and mortality rates due to effective control of occupational asbestos use, but the rates among women remain stable, suggesting other sources of exposure.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Health Care Sciences & Services
Antonietta Porzio, Alessandro Feola, Giuseppe Parisi, Angelo Lauro, Carlo Pietro Campobasso
Summary: This study reviewed 35 claims of occupational colorectal cancer among asbestos-exposed workers and identified some interesting characteristics, providing clues for the assessment of the causal relationship between asbestos exposure and colorectal cancer.
Article
Oncology
Hugo Noelle, Olivia Perol, Maurice Perol, Virginie Avrillon, Elodie Belladame, Jerome Fayette, Francoise Fournie, Aurelie Swalduz, Juliette Dessemon, Jean-Yves Blay, Eve-Marie Neidhardt, Pierre Saintigny, Mayeul Tabutin, Maxime Boussageon, Delphine Praud, Barbara Charbotel, Beatrice Fervers
Summary: This study investigated the association between occupational asbestos exposure (OAE) and survival in patients with lung cancer (LC). The results showed that LCs moderately or highly attributable to OAE were associated with decreased overall survival. However, after adjusting for confounding factors, this association became non-significant.
Article
Environmental Sciences
Claudio Gariazzo, Alessandra Binazzi, Marco Alfo, Stefania Massari, Massimo Stafoggia, Alessandro Marinaccio
Summary: This study assessed the influence of occupational and environmental factors on lung cancer risk in Italy, finding that asbestos, PM2.5, and radon exposure have a significant impact on lung cancer mortality rates. By studying these factors, we can increase awareness of the origin of lung cancer and improve equity in the welfare system.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2021)
Article
Public, Environmental & Occupational Health
David B. Richardson, Alexander P. Keil, Stephen R. Cole
Summary: This study highlights that the net bias in an estimation of the association of interest may increase when adjusting for confounders in the presence of classical exposure measurement error.
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2022)
Article
Public, Environmental & Occupational Health
Giehae Choi, Jessie P. Buckley, Jordan R. Kuiper, Alexander P. Keil
Summary: Research suggests that the best overall model fit reflects the underlying outcome generating methods with the least bias when the skewness of exposure is not due to a biasing factor, while all estimates are biased if the skewness of exposure is a consequence of a biasing factor. Separating the shape of the exposure distribution from the decision to log-transform it may aid researchers in planning for analysis using biomarkers or other skewed independent variables.
Letter
Public, Environmental & Occupational Health
Rachael K. Ross, Alexander P. Keil, Stephen R. Cole, Jessie K. Edwards, Jeffrey S. A. Stringer
AMERICAN JOURNAL OF EPIDEMIOLOGY
(2023)
Article
Public, Environmental & Occupational Health
Knut Ringen, John Dement, Laura Welch, Patricia Quinn
Summary: This study used data from a medical screening program for older construction workers to examine the improvements in health outcomes over the past 60 years. The results showed that the adoption of occupational health protections has led to significant reductions in risks associated with diseases such as chronic obstructive pulmonary disease, pneumoconiosis, hearing impairment, and lung cancer mortality. The study also found that the greatest risk reductions occurred among workers first employed after 1970, and that the improvements in hearing impairment were the lowest.
AMERICAN JOURNAL OF INDUSTRIAL MEDICINE
(2023)
Letter
Environmental Sciences
Alexander P. Keil, Jessie P. Buckley, Katie M. O'Brien, Kelly K. Ferguson, Alexandra J. White
ENVIRONMENTAL HEALTH PERSPECTIVES
(2023)
Article
Public, Environmental & Occupational Health
Morgan Miller Richey, Yvonne Golightly, Stephen William Marshall, Wendy Novicoff, Alexander Keil, Maryalice Nocera, David B. Richardson
Summary: This study conducted in North Carolina found that older workers have a higher risk of fatal occupational injury. The research results showed that the rate of fatal occupational injury among older workers did not significantly decrease before and after the economic recession.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Biology
Audrey Renson, Michael G. Hudgens, Alexander P. Keil, Paul N. Zivich, Allison E. Aiello
Summary: This article examines sustained interventions in public health and medicine and proposes a method for evaluating population effects. The method is validated through simulation studies and applied to estimate the effect of a stay-at-home order on all-cause mortality during the COVID-19 pandemic.
Article
Public, Environmental & Occupational Health
Kieran Blaikie, Jerzy Eisenberg-Guyot, Sarah B. B. Andrea, Shanise Owens, Anita Minh, Alexander P. P. Keil, Anjum Hajat
Summary: In the United States, there is an increasing inequity in mental distress between those with different levels of education. Employment quality, as a multidimensional construct, may play a mediating role in this inequity. However, no study has investigated the extent of this mediation and its variations across racial and gender groups in the United States.
Article
Public, Environmental & Occupational Health
Amber M. Hall, Amanda M. Ramos, Samantha SM. Drover, Giehae Choi, Alexander P. Keil, David B. Richardson, Chantel L. Martin, Andrew F. Olshan, Gro D. Villanger, Ted Reichborn-Kjennerud, Pal Zeiner, Kristin R. overgaard, Amrit K. Sakhi, Cathrine Thomsen, Heidi Aase, Stephanie M. Engel
Summary: This study found a modest increased odds of preschool ADHD with higher DnBP and BDCIPP exposure.
INTERNATIONAL JOURNAL OF HYGIENE AND ENVIRONMENTAL HEALTH
(2023)
Article
Multidisciplinary Sciences
Josee M. Dussault, Chifundo Zimba, Harriet E. Akello, Melissa Stockton, Sherika N. Hill, Allison Aiello, Alexander W. Keil, Bradley Gaynes, Michael Udedi, Brian Pence
Summary: While research on mental health stigma in Malawi is lacking, studies in other contexts suggest that stigma is a barrier to mental health treatment and recovery. This study analyzed the role of treatment-related stigma in depression care in Malawi and found that high anticipated treatment stigma was associated with a lower probability of achieving depression remission at the 3-month mark.
Review
Public, Environmental & Occupational Health
Alexander P. Keil, Sabrina Zadrozny, Jessie K. Edwards
Summary: Multi-level models are used to model data using multiple levels of information. This review examines how multi-level models can be used for causal inference with individual level exposures. The review clarifies and synthesizes complex ideas in the literature and discusses how multi-level models can relax some identifying conditions of causal inference. However, there are gaps in the literature on causal inference with multi-level models, but some published approaches are provided for further guidance. Practical advice is given on when to use multi-level models for causal inference and how to go beyond interpreting their parameters.
CURRENT EPIDEMIOLOGY REPORTS
(2023)
Article
Public, Environmental & Occupational Health
Tyler J. S. Smith, Alexander P. Keil, Jessie P. Buckley
Summary: This review discusses how epidemiologic studies have used observational data to estimate the effects of potential interventions on early-life environmental exposures. The findings suggest a growing interest in estimating intervention effects on early-life environmental exposures, as they are directly related to possible public health actions. Future studies can link research questions to specific hypothetical interventions to build on existing work.
CURRENT ENVIRONMENTAL HEALTH REPORTS
(2023)
Meeting Abstract
Developmental Biology
P. A. Bommarito, B. M. Welch, A. P. Keil, D. E. Cantonwine, T. F. Mcelrath, K. K. Ferguson
BIRTH DEFECTS RESEARCH
(2022)
Article
Environmental Sciences
Ibrahim Zaganjor, Alexander P. Keil, Thomas J. Luben, Tania A. Desrosiers, Lawrence S. Engel, Jennita Reefhuis, Adrian M. Michalski, Peter H. Langlois, Andrew F. Olshan
Summary: This study explored the potential for misclassification of residence-based environmental exposure as a result of not accounting for the workplace environments of employed pregnant women. Through simulations, it was found that household estimates may be sufficient proxies for worksite exposures to haloacetic acids in tap water.
ENVIRONMENTAL EPIDEMIOLOGY
(2022)
Meeting Abstract
Obstetrics & Gynecology
Barrett M. Welch, Alexander P. Keil, Jessie P. Buckley, Antonia M. Calafat, Kate E. Christenbury, Stephanie M. Engel, Katie M. O'Brien, M. Rosen Rosen, Kelly K. Ferugson
REPRODUCTIVE SCIENCES
(2022)