Curcuminoids Induce Reactive Oxygen Species and Autophagy to Enhance Apoptosis in Human Oral Cancer Cells

Casticin Induced Apoptosis in A375.S2 Human Melanoma Cells through the Inhibition of NF-κB and Mitochondria-Dependent Pathways In Vitro and Inhibited Human Melanoma Xenografts in a Mouse Model In Vivo

(2016) Yin-Wen Shiue et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Apple pectin: A natural source for cancer suppression in 4T1 breast cancer cells in vitro and express p53 in mouse bearing 4T1 cancer tumors, in vivo

(2016) Ladan Delphi et al.   BIOMEDICINE & PHARMACOTHERAPY

Curcumin induces G0/G1 arrest and apoptosis in hormone independent prostate cancer DU-145 cells by down regulating Notch signaling

(2016) Jian Sha et al.   BIOMEDICINE & PHARMACOTHERAPY

Anticancer effects of cantharidin in A431 human skin cancer (Epidermoid carcinoma) cells in vitro and in vivo

(2016) Chi-Chuan Li et al.   ENVIRONMENTAL TOXICOLOGY

Tetrandrine induces programmed cell death in human oral cancer CAL 27 cells through the reactive oxygen species production and caspase-dependent pathways and associated with beclin-1-induced cell autophagy

(2016) Jin-Cherng Lien et al.   ENVIRONMENTAL TOXICOLOGY

Curcumin inhibits invasive capabilities through epithelial mesenchymal transition in breast cancer cell lines

(2016) Marcela Gallardo et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Oral cancer: Etiology and risk factors: A review

(2016) Malay Kumar et al.   Journal of Cancer Research and Therapeutics

Curcumin induced apoptosis via PI3K/Akt-signalling pathways in SKOV3 cells

(2016) Zeshun Yu et al.   PHARMACEUTICAL BIOLOGY

Systemic application of 3-methyladenine markedly inhibited atherosclerotic lesion in ApoE−/− mice by modulating autophagy, foam cell formation and immune-negative molecules

(2016) Shen Dai et al.   Cell Death & Disease

Bisdemethoxycurcumin inhibits ovarian cancer via reducing oxidative stress mediated MMPs expressions

(2016) Haifeng Pei et al.   Scientific Reports

Chloroform Extract of Solanum lyratum Induced G0/G1 Arrest via p21/p16 and Induced Apoptosis via Reactive Oxygen Species, Caspases and Mitochondrial Pathways in Human Oral Cancer Cell Lines

(2015) Chiz-Hao Chiu et al.   AMERICAN JOURNAL OF CHINESE MEDICINE

Crude extract ofEuphorbia formosanainduces apoptosis of DU145 human prostate cancer cells acts through the caspase-dependent and independent signaling pathway

(2015) Jiun-Long Yang et al.   ENVIRONMENTAL TOXICOLOGY

Bisdemethoxycurcumin-induced S phase arrest through the inhibition of cyclin A and E and induction of apoptosis via endoplasmic reticulum stress and mitochondria-dependent pathways in human lung cancer NCI H460 cells

(2015) Su-Tso Yang et al.   ENVIRONMENTAL TOXICOLOGY

Bioactive compounds from crocodile (Crocodylus siamensis) white blood cells induced apoptotic cell death in hela cells

(2015) Supawadee Patathananone et al.   ENVIRONMENTAL TOXICOLOGY

Bisdemethoxycurcumin Induces Apoptosis in Activated Hepatic Stellate Cells via Cannabinoid Receptor 2

(2015) Phil Lee et al.   MOLECULES

Cell death by autophagy: emerging molecular mechanisms and implications for cancer therapy

(2015) S Fulda et al.   ONCOGENE

Demethoxycurcumin induces the apoptosis of human lung cancer NCI-H460 cells through the mitochondrial-dependent pathway

(2015) YANG-CHING KO et al.   ONCOLOGY REPORTS

How Does Multistep Tumorigenesis Really Proceed?

(2015) Christine L. Chaffer et al.   Cancer Discovery

Oxidative stress and autophagy: the clash between damage and metabolic needs

(2014) G Filomeni et al.   CELL DEATH AND DIFFERENTIATION

Autophagy as a pro-death pathway

(2014) Donna Denton et al.   IMMUNOLOGY AND CELL BIOLOGY

Bacteria–autophagy interplay: a battle for survival

(2014) Ju Huang et al.   NATURE REVIEWS MICROBIOLOGY

Curcumin and Dimethoxycurcumin Induced Epigenetic Changes in Leukemia Cells

(2014) Hazem E. Hassan et al.   PHARMACEUTICAL RESEARCH

Curcumin, demethoxycurcumin and bisdemethoxycurcumin differentially inhibit morphine's rewarding effect in rats

(2014) Vicky Katsidoni et al.   PSYCHOPHARMACOLOGY

Stronger proteasomal inhibition and higher CHOP induction are responsible for more effective induction of paraptosis by dimethoxycurcumin than curcumin

(2014) M J Yoon et al.   Cell Death & Disease

Regulation of autophagy by polyphenolic compounds as a potential therapeutic strategy for cancer

(2014) N Hasima et al.   Cell Death & Disease

Apoptosis induction by an analog of curcumin (BDMC-A) in human laryngeal carcinoma cells through intrinsic and extrinsic pathways

(2014) Kumaravel Mohankumar et al.   CELLULAR ONCOLOGY

Histone modifications: Targeting head and neck cancer stem cells

(2014) John Le   World Journal of Stem Cells

Autophagy modulation as a target for anticancer drug discovery

(2013) Xin Li et al.   ACTA PHARMACOLOGICA SINICA

Autophagy and chemotherapy resistance: a promising therapeutic target for cancer treatment

(2013) X Sui et al.   Cell Death & Disease

The interplay between autophagy and ROS in tumorigenesis

(2012) Sameera Kongara et al.   Frontiers in Oncology

Dimethoxycurcumin-induced cell death in human breast carcinoma MCF7 cells: evidence for pro-oxidant activity, mitochondrial dysfunction, and apoptosis

(2011) A. Kunwar et al.   ARCHIVES OF TOXICOLOGY

The Beclin 1 network regulates autophagy and apoptosis

(2011) R Kang et al.   CELL DEATH AND DIFFERENTIATION

The rate of oxygen utilization by cells

(2011) Brett A. Wagner et al.   FREE RADICAL BIOLOGY AND MEDICINE

Differential antioxidant/pro-oxidant activity of dimethoxycurcumin, a synthetic analogue of curcumin

(2011) Amit Kunwar et al.   FREE RADICAL RESEARCH

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Tubular network formation protects mitochondria from autophagosomal degradation during nutrient starvation

(2011) A. S. Rambold et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting apoptosis pathways by natural compounds in cancer: Marine compounds as lead structures and chemical tools for cancer therapy

(2010) Karin von Schwarzenberg et al.   CANCER LETTERS

Synergistic Role of Curcumin With Current Therapeutics in Colorectal Cancer: Minireview

(2009) Bhaumik B. Patel et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL