A Systematic Review on the Protective Effect of N-Acetyl Cysteine Against Diabetes-Associated Cardiovascular Complications

Sulfiredoxin involved in the protection of peroxiredoxins against hyperoxidation in the early hyperglycaemia

(2017) Sa Shi et al.   EXPERIMENTAL CELL RESEARCH

Aspalathin Protects the Heart against Hyperglycemia-Induced Oxidative Damage by Up-Regulating Nrf2 Expression

(2017) Phiwayinkosi Dludla et al.   MOLECULES

Hyperglycemia-induced oxidative stress and heart disease-cardioprotective effects of rooibos flavonoids and phenylpyruvic acid-2-O-β-D-glucoside

(2017) Phiwayinkosi V. Dludla et al.   Nutrition & Metabolism

N-acetylcysteine attenuates myocardial dysfunction and postischemic injury by restoring caveolin-3/eNOS signaling in diabetic rats

(2016) Wating Su et al.   Cardiovascular Diabetology

Cardioprotection from emulsified isoflurane postconditioning is lost in rats with streptozotocin-induced diabetes due to the impairment of Brg1/Nrf2/STAT3 signalling

(2016) Y. Wang et al.   CLINICAL SCIENCE

N-Acetyl cysteine protects diabetic mouse derived mesenchymal stem cells from hydrogen-peroxide-induced injury: A novel hypothesis for autologous stem cell transplantation

(2016) Fatima Ali et al.   Journal of the Chinese Medical Association

Aspalathin, a dihydrochalconeC-glucoside, protects H9c2 cardiomyocytes against high glucose induced shifts in substrate preference and apoptosis

(2016) Rabia Johnson et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Matrine pretreatment improves cardiac function in rats with diabetic cardiomyopathy via suppressing ROS/TLR-4 signaling pathway

(2015) Zhong-wei Liu et al.   ACTA PHARMACOLOGICA SINICA

Palmitoyl-carnitine increases RyR2 oxidation and sarcoplasmic reticulum Ca2+ leak in cardiomyocytes: Role of adenine nucleotide translocase

(2015) J. Roussel et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

N-Acetyl Cysteine improves the diabetic cardiac function: possible role of fibrosis inhibition

(2015) Cong Liu et al.   BMC Cardiovascular Disorders

Chemerin Regulates Crosstalk Between Adipocytes and Vascular Cells Through NoxNovelty and Significance

(2015) Karla Bianca Neves et al.   HYPERTENSION

Effects of N-acetylcysteine, oral glutathione (GSH) and a novel sublingual form of GSH on oxidative stress markers: A comparative crossover study.

(2015) Bernard Schmitt et al.   Redox Biology

Genetically Low Antioxidant Protection and Risk of Cardiovascular Disease and Heart Failure in Diabetic Subjects

(2015) Camilla J. Kobylecki et al.   EBioMedicine

Metformin and Resveratrol Inhibited High Glucose-Induced Metabolic Memory of Endothelial Senescence through SIRT1/p300/p53/p21 Pathway

(2015) Erli Zhang et al.   PLoS One

Hyperglycemic and Hyperlipidemic Conditions Alter Cardiac Cell Biomechanical Properties

(2014) Jarett Michaelson et al.   BIOPHYSICAL JOURNAL

Coronary Artery Disease and Diabetes Mellitus

(2014) Doron Aronson et al.   CARDIOLOGY CLINICS

N-Acetylcysteine prevents congenital heart defects induced by pregestational diabetes

(2014) Hoda Moazzen et al.   Cardiovascular Diabetology

Pregestational Diabetes Induces Fetal Coronary Artery Malformation via Reactive Oxygen Species Signaling

(2014) Hoda Moazzen et al.   DIABETES

Arachidonate 12/15-Lipoxygenase–Induced Inflammation and Oxidative Stress Are Involved in the Development of Diabetic Cardiomyopathy

(2014) Hirofumi Suzuki et al.   DIABETES

Beta-blocker timolol alleviates hyperglycemia-induced cardiac damage via inhibition of endoplasmic reticulum stress

(2014) Figen Amber Cicek et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

The Prevalence of Diabetic Cardiomyopathy: A Population-Based Study in Olmsted County, Minnesota

(2014) Sanjay Dandamudi et al.   JOURNAL OF CARDIAC FAILURE

Enhancement of Cellular Antioxidant-Defence Preserves Diastolic Dysfunction via Regulation of Both Diastolic Zn2+and Ca2+and Prevention of RyR2-Leak in Hyperglycemic Cardiomyocytes

(2014) Erkan Tuncay et al.   Oxidative Medicine and Cellular Longevity

Diabetic cardiomyopathy: Mechanisms and new treatment strategies targeting antioxidant signaling pathways

(2014) Karina Huynh et al.   PHARMACOLOGY & THERAPEUTICS

Systematic review of N-acetylcysteine in the treatment of addictions

(2014) Elson Asevedo et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Non‐Communicable Diseases (NCDs) in developing countries: a symposium report

(2014) Sheikh Mohammed Shariful Islam et al.   Globalization and Health

Cardioprotection during Diabetes

(2013) Maria Muravyeva et al.   ANESTHESIOLOGY

Chronic resveratrol administration improves diabetic cardiomyopathy in part by reducing oxidative stress

(2013) Majid Mohammadshahi et al.   Cardiology Journal

Protein kinase RNA- like endoplasmic reticulum kinase (PERK) signaling pathway plays a major role in reactive oxygen species (ROS)- mediated endoplasmic reticulum stress- induced apoptosis in diabetic cardiomyopathy

(2013) Zhong-Wei Liu et al.   Cardiovascular Diabetology

Relationship Between Downregulation of miRNAs and Increase of Oxidative Stress in the Development of Diabetic Cardiac Dysfunction: Junctin as a Target Protein of miR-1

(2013) Samet Serdar Yildirim et al.   CELL BIOCHEMISTRY AND BIOPHYSICS

Is Glucose Control Important for Prevention of Cardiovascular Disease in Diabetes?

(2013) E. Mannucci et al.   DIABETES CARE

Taxifolin prevents diabetic cardiomyopathy in vivo and in vitro by inhibition of oxidative stress and cell apoptosis

(2013) Xiao Sun et al.   FOOD AND CHEMICAL TOXICOLOGY

N-Acetylcysteine and allopurinol up-regulated the Jak/STAT3 and PI3K/Akt pathways via adiponectin and attenuated myocardial postischemic injury in diabetes

(2013) Tingting Wang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Exogenous hydrogen sulfide protects H9c2 cardiac cells against high glucose-induced injury by inhibiting the activities of the p38 MAPK and ERK1/2 pathways

(2013) WENMING XU et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Prevention by sulforaphane of diabetic cardiomyopathy is associated with up-regulation of Nrf2 expression and transcription activation

(2013) Yang Bai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The cardioprotective effect of an aqueous extract of fermented rooibos (Aspalathus linearis) on cultured cardiomyocytes derived from diabetic rats

(2013) P.V. Dludla et al.   PHYTOMEDICINE

α-Lipoic acid increases tolerance of cardiomyoblasts to glucose/glucose oxidase-induced injury via ROS-dependent ERK1/2 activation

(2012) Yuzhen Yao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Impact of N-acetylcysteine on Endothelial Function, B-type Natriuretic Peptide and Renal Function in Patients with the Cardiorenal Syndrome: A Pilot Cross Over Randomised Controlled Trial

(2012) Anthony C. Camuglia et al.   Heart Lung and Circulation

Diallyl trisufide (DATS) suppresses high glucose-induced cardiomyocyte apoptosis by inhibiting JNK/NFκB signaling via attenuating ROS generation

(2012) Wei-Wen Kuo et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Oxidative stress and myocardial injury in the diabetic heart

(2012) David M Ansley et al.   JOURNAL OF PATHOLOGY

Effects of N-Acetylcysteine on Nicotinamide Dinucleotide Phosphate Oxidase Activation and Antioxidant Status in Heart, Lung, Liver and Kidney in Streptozotocin-Induced Diabetic Rats

(2012) Shaoqing Lei et al.   YONSEI MEDICAL JOURNAL

Metformin improves cardiac function in a nondiabetic rat model of post-MI heart failure

(2011) Meimei Yin et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Adaptive induction of NF-E2-related factor-2-driven antioxidant genes in endothelial cells in response to hyperglycemia

(2011) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

N-acetylcysteine Offers Cardioprotection by Decreasing Cardiac Lipid Hydroperoxides and 8-Isoprostane Level in Isoproterenol-Induced Cardiotoxicity in Rats

(2011) Nagaraja Haleagrahara et al.   Cardiovascular Toxicology

PKCβ inhibition with ruboxistaurin reduces oxidative stress and attenuates left ventricular hypertrophy and dysfuntion in rats with streptozotocin-induced diabetes

(2011) Yanan Liu et al.   CLINICAL SCIENCE

Type 2 diabetes and cardiovascular risk factors

(2011) Morali D. Sharma et al.   CURRENT MEDICAL RESEARCH AND OPINION

Ascorbic acid and N-acetyl cysteine prevent uncoupling of nitric oxide synthase and increase tolerance to ischemia/reperfusion injury in diabetic rat heart

(2011) Toru Okazaki et al.   FREE RADICAL RESEARCH

Suppression of high pacing-induced ANP secretion by antioxidants in isolated rat atria

(2011) Shan Gao et al.   PEPTIDES

N-Acetylcysteine and Allopurinol Synergistically Enhance Cardiac Adiponectin Content and Reduce Myocardial Reperfusion Injury in Diabetic Rats

(2011) Tingting Wang et al.   PLoS One

Resveratrol confers endothelial protection via activation of the antioxidant transcription factor Nrf2

(2010) Zoltan Ungvari et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Oxidative Stress and Diabetic Complications

(2010) Ferdinando Giacco et al.   CIRCULATION RESEARCH

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

(2010) Carol Kilkenny et al.   PLOS BIOLOGY

The protease inhibitor UCF-101 ameliorates streptozotocin-induced mouse cardiomyocyte contractile dysfunctionin vitro: role of AMP-activated protein kinase

(2009) Qun Li et al.   EXPERIMENTAL PHYSIOLOGY

Acetylcysteine for Acetaminophen Poisoning

(2008) Kennon J. Heard   NEW ENGLAND JOURNAL OF MEDICINE