Male lifespan extension with 17-α estradiol is linked to a sex-specific metabolomic response modulated by gonadal hormones in mice

Testosterone prevents protein loss via the hepatic urea cycle in human

(2017) Teresa Lam et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Sex-dependent Differences in Liver and Gut Metabolomic Profiles With Acarbose and Calorie Restriction in C57BL/6 Mice

(2017) Victoria K Gibbs et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Androgen-mediated regulation of skeletal muscle protein balance

(2017) Michael L. Rossetti et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α-glucosidase inhibitor or a Nrf2-inducer

(2016) Randy Strong et al.   AGING CELL

Life history evolution, reproduction, and the origins of sex-dependent aging and longevity

(2016) Robert C. Brooks et al.   Annals of the New York Academy of Sciences

17α-Estradiol: A Novel Therapeutic Intervention to Target Age-related Chronic Inflammation

(2016) Marta Gonzalez-Freire et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Individual variability in human blood metabolites identifies age-related differences

(2016) Romanas Chaleckis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

(2016) Zeynep Madak-Erdogan et al.   Science Signaling

Cell culture-based profiling across mammals reveals DNA repair and metabolism as determinants of species longevity

(2016) Siming Ma et al.   eLife

Design of pathway preferential estrogens that provide beneficial metabolic and vascular effects without stimulating reproductive tissues

(2016) Zeynep Madak-Erdogan et al.   Science Signaling

Long-term effects of castration on the skeleton of male rhesus monkeys (Macaca mulatta)

(2015) Matthew J. Kessler et al.   AMERICAN JOURNAL OF PRIMATOLOGY

Ovariectomy shortens the life span of female mice

(2015) Valeria Benedusi et al.   Oncotarget

Sex differences in metabolic homeostasis, diabetes, and obesity

(2015) Franck Mauvais-Jarvis   Biology of Sex Differences

Dietary restriction of rodents decreases aging rate without affecting initial mortality rate - a meta-analysis

(2013) Mirre J. P. Simons et al.   AGING CELL

Acarbose, 17-α-estradiol, and nordihydroguaiaretic acid extend mouse lifespan preferentially in males

(2013) David E. Harrison et al.   AGING CELL

Rapamycin-mediated lifespan increase in mice is dose and sex dependent and metabolically distinct from dietary restriction

(2013) Richard A. Miller et al.   AGING CELL

Gender and longevity: Why do men die earlier than women? Comparative and experimental evidence

(2013) Jennifer C. Regan et al.   BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM

The lifespan of Korean eunuchs

(2012) Kyung-Jin Min et al.   CURRENT BIOLOGY

Mass spectral molecular networking of living microbial colonies

(2012) J. Watrous et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MSEA: a web-based tool to identify biologically meaningful patterns in quantitative metabolomic data

(2010) J. Xia et al.   NUCLEIC ACIDS RESEARCH

Review of the effects of 17α-estradiol in humans: a less feminizing estrogen with neuroprotective potential

(2009) Walter H. Moos et al.   DRUG DEVELOPMENT RESEARCH

Transplantation of Young Ovaries to Old Mice Increased Life Span in Transplant Recipients

(2009) J. B. Mason et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Sex Differences in the Expression of Hepatic Drug Metabolizing Enzymes

(2009) D. J. Waxman et al.   MOLECULAR PHARMACOLOGY

Nordihydroguaiaretic acid and aspirin increase lifespan of genetically heterogeneous male mice

(2008) Randy  Strong et al.   AGING CELL