Article
Biochemistry & Molecular Biology
Min-Rui Tai, Hong-Wu Ji, Jian-Ping Chen, Xiao-Fei Liu, Bing-Bing Song, Sai-Yi Zhong, Aaqil Rifai, David R. Nisbet, Colin J. Barrow, Richard J. Williams, Rui Li
Summary: This study develops a method using nanogels as delivery tools to successfully deliver and control the release of hydrophobic bioactive compound hesperidin. The coassembly of self-assembled peptide and polysaccharide nanogels improves mechanical properties, encapsulation efficiency, and controlled release of hesperidin.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2023)
Article
Engineering, Biomedical
Zhou Ye, Xiao Zhu, Isha Mutreja, Sunil Kumar Boda, Nicholas G. Fischer, Anqi Zhang, Christine Lui, Yipin Qi, Conrado Aparicio
Summary: The study developed a scaffold with dual function for promoting tissue growth and preventing bacterial infections. The scaffolds were fabricated through intrafibrillar-mineralization of collagen and coating with antimicrobial peptides, demonstrating both antimicrobial properties and cytocompatibility to human cells. The process of scaffold fabrication is versatile and can be used with other biopolymers for controlling mineral load.
BIOACTIVE MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Shuai Zhang, Jeevapani J. J. Hettige, Yuhao Li, Tengyue Jian, Wenchao Yang, Yun-Chiao Yao, Renyu Zheng, Zhixing Lin, Jinhui Tao, James J. J. De Yoreo, Marcel Baer, Aleksandr Noy, Chun-Long Chen
Summary: Finding a stable and highly selective artificial membrane is crucial for solving global crises such as water scarcity. The co-assembly of carbon nanotube porins (CNTPs) and peptoids into 2D membrane nanosheets offers a promising solution with superior crystallinity and robustness.
Article
Chemistry, Multidisciplinary
Peiwen Liu, Jiaxiu Wang, Houjuan Qi, Tim Koddenberg, Dan Xu, Siyuan Liu, Kai Zhang
Summary: This study presents a novel method for self-assembly using chitin nanocrystals in capillaries. The fixed-boundary evaporation-induced self-assembly (FB-EISA) modality is employed, where a fixed air-liquid interface at the end of capillaries serves as the evaporation interface and initial deposition site of chitin nanocrystals. Through successive evaporation, continuous birefringent structures with a density gradient are generated, leading to the formation of cylindrical tubes.
Article
Chemistry, Multidisciplinary
Tomoyuki Koga, Aika Ikejiri, Nobuyuki Higashi
Summary: In this study, the hierarchical self-assembly and self-sorting of collagen-inspired peptides (CPs) were described. The CPs formed triple helix structures when cooled, which further self-assembled into highly ordered vesicles. Interestingly, the CPs exhibited narcissistic self-sorting behavior during the formation of both triple helix and matured vesicles. Due to the difference in triple helix formation at different temperatures, the CPs discriminated each other and formed distinct foldamers. These findings provide important insights for the design of complex and ordered peptide self-assembly systems with potential applications in nanobiotechnology.
Article
Chemistry, Multidisciplinary
Min Fu, Wei Chen, Yu Lei, Hao Yu, Yuxiao Lin, Mauricio Terrones
Summary: A general biomimetic mineralization synthetic strategy was proposed to synthesize ferrite quantum dot/graphene heterostructures. The optimized heterostructure exhibited exceptional capacitance and cycling performance, indicating its potential as advanced electrode materials for supercapacitors.
ADVANCED MATERIALS
(2023)
Article
Biochemistry & Molecular Biology
Genpei Zhang, Kai Yue, Anqi Wang, Weishen Zhong, Peipei Yang, Lei Wang, Xinwei Ye, Xiaochen Sun
Summary: This study investigated the mechanisms of self-assembly and disassembly of biomimetic peptides with different components and sequences. The results show that hydrophobic and hydrophilic interactions play crucial roles in the self-assembly and disassembly processes, and polyethylene glycol chain modification is necessary for disassembly.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES
(2022)
Article
Chemistry, Applied
Xiaomin Ma, Lei Ma, Yunfei Tan, Xiangyu Chen, Qiulan Tong, Liwen Tang, Xiaoyu Cao, Danni Liu, Xudong Li
Summary: Biomolecules-mediated biomimetic mineralization has been extensively studied and applied to fabricate nano-assemblies with unique hierarchical architectures and properties. In this research, a confined diffusion method was used to mimic the in vivo condition, resulting in the formation of hydroxyapatite nanoflower assemblies (HNAs) with delicate hierarchical architectures. The study revealed that strong interactions between ions and hyaluronan played a crucial role in the nucleation and aggregation of hydroxyapatite, and the self-assembling process was induced by external diffusion field and internal multiple interactions. Moreover, HNAs showed colloid stability and excellent biocompatibility, making them a promising carrier for intranuclear delivery.
CARBOHYDRATE POLYMERS
(2023)
Article
Chemistry, Multidisciplinary
Shine K. Albert, Sunghee Lee, Prasannavenkatesh Durai, Xiaole Hu, Byeongmoon Jeong, Keunwan Park, So-Jung Park
Summary: The study demonstrates the fabrication of Janus nanosheets from molecular building blocks composed of DNA and peptides, and reveals the formation of nanosheets with distinct DNA and peptide faces. The surprisingly level of structural control is attributed to the exclusive parallel beta-sheet formation of phenylalanine-rich peptides. Furthermore, the predictable and designable peptide interaction is shown to be a promising tool for creating Janus nanostructures with regio-selective and sequence-specific molecular recognition properties.
Review
Chemistry, Multidisciplinary
Jingjing Han, Haoning Gong, Xiaokang Ren, Xuehai Yan
Summary: This article introduces the research field of peptide-based supramolecular nanozymes, emphasizing the importance and versatility of peptides as building blocks, as well as the potential for regulating catalytic performance.
Article
Materials Science, Multidisciplinary
Sajad Abolpour Moshizi, Hamed Moradi, Shuying Wu, Zhao Jun Han, Amir Razmjou, Mohsen Asadnia
Summary: In this study, a novel flow sensor based on PVA hydrogel nanocomposites and graphene nanosheets is developed, showing high sensitivity and extremely low velocity detection capability. The sensor is highly sensitive to tiny stimuli underwater and suitable for biomedical applications.
ADVANCED MATERIALS TECHNOLOGIES
(2022)
Article
Materials Science, Biomaterials
Danzhu Zhu, Peng He, Hao Kong, Guozheng Yang, Xin Luan, Gang Wei
Summary: The peptide-mediated biomimetic synthesis of ultrafine platinum nanowires (PtNWs) on graphene oxide (GO) nanosheets for the formation of functional hybrids is presented for the detection of hydrogen peroxide (H2O2). The PtNWs-PNFs/GO hybrids show high potential for the fabrication of colorimetric and electrochemical sensors with high performance. The dual-mode sensor platform allows for both colorimetric and electrochemical sensing of H2O2 with high selectivity and sensitivity.
JOURNAL OF MATERIALS CHEMISTRY B
(2022)
Article
Nanoscience & Nanotechnology
Yitao Wu, Qi Li, Jiajun Cao, Yang Liu, Zeju Wang, Liqing Shangguan, Huangtianzhi Zhu
Summary: Inspired by natural cross-linking and biomineralization processes, a pillararenepeptide nanogel is constructed as a platform for biomimetic mineralization and heterogeneous catalysis. The nanogel, with a spherical morphology and high stability, immobilizes Pt species via biomimetic mineralization to form a hybrid material with abundant Pt nanoparticles. This hybrid material is utilized in heterogeneous catalysis for the reduction of nitroaromatic compounds, demonstrating excellent recyclability in at least ten runs without changes in morphology or activity. By applying bioinspired methods in pillararene chemistry, this work may provide insight into designing functional nanomaterials.
ACS APPLIED NANO MATERIALS
(2021)
Article
Chemistry, Multidisciplinary
Wei Qian, Huaqiang Fu, Yi Sun, Zhe Wang, Han Wu, Zongkui Kou, Bao-Wen Li, Daping He, Ce-Wen Nan
Summary: Through an electrostatic-repulsion aligning strategy, highly conductive, ultraflexible, and multifunctional graphene films with fine microstructure, enhanced mechanical properties, and improved electrical conductivity have been produced.
ADVANCED MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Chen Ye, Yangguang Zhu, Hongyan Sun, Feiyue Chen, Huifang Sun, Wen Dai, Qiuping Wei, Li Fu, Aimin Yu, Shiyu Du, Minghui Yang, Liang-Feng Huang, Jinhong Yu, Nan Jiang, Cheng-Te Lin
Summary: Graphene nanosheets are widely used in anti-corrosion polymeric coating as filler due to their excellent electrochemical inertness and barrier property. However, the difficulty in forming a perfect layered structure leads to the need for micron-scale thickness in polymeric coatings with graphene nanosheets. In this study, layer-by-layer stacked graphene nanocoatings were fabricated on stainless steel using a self-assembly method based on the Marangoni effect. The anti-corrosion properties of the graphene coatings were evaluated, with the optimized three-layered graphene-coated sample showing significantly lower self-corrosion current density compared to bare stainless steel.
CHINESE CHEMICAL LETTERS
(2021)
Review
Chemistry, Analytical
Tao Li, Dawei Shang, Shouwu Gao, Bo Wang, Hao Kong, Guozheng Yang, Weidong Shu, Peilong Xu, Gang Wei
Summary: This review discusses the recent advances in fabrication of 2DM-based electrochemical sensors and biosensors for applications in food safety and biomolecular detection related to human health. It includes the synthesis methods, structure, and surface chemistry of various 2DMs, as well as their applications in detecting nitrite, heavy metal ions, antibiotics, pesticides, and key small molecules for disease monitoring.
Review
Materials Science, Multidisciplinary
Zixuan Xiao, Shujing Zhao, Xiaoyuan Zhang, Gang Wei, Zhiqiang Su
Summary: This review presents recent advances in the functionalization of PEG hydrogels with peptides for biomedical applications, including preparation methods, functional regulation, and specific applications. This work provides a systematic literature review on this promising topic and facilitates readers in the design of composite materials and functional tailoring of PEG hydrogels with biomolecules.
MACROMOLECULAR MATERIALS AND ENGINEERING
(2022)
Article
Engineering, Environmental
Shujing Zhao, Xin Zhang, Gang Wei, Zhiqiang Su
Summary: The researchers designed a three-dimensional all-weather solar evaporator that can efficiently enhance solar-driven water purification. The material exhibits high broadband light absorption, fast water transport, and good thermal management properties. It also has excellent salt resistance, making it suitable for applications such as wastewater treatment, seawater desalination, and solar steam generation.
CHEMICAL ENGINEERING JOURNAL
(2023)
Review
Chemistry, Multidisciplinary
Xin Luan, Hao Kong, Peng He, Guozheng Yang, Danzhu Zhu, Lei Guo, Gang Wei
Summary: This article summarizes the design, synthesis, functional regulation, and applications of peptide-based nanodrugs. It firstly presents the molecular design and controllable synthesis of peptide nanodrugs, followed by the discussion of functional customization strategies. The applications of peptide-based nanodrugs in bioimaging, chemotherapy, photothermal therapy, and photodynamic therapy are demonstrated and discussed in detail. Furthermore, the status and challenges of peptide-based drugs in preclinical, clinical trials, and approval are briefly described.
Article
Chemistry, Analytical
Danzhu Zhu, Hao Kong, Guozheng Yang, Peng He, Xin Luan, Lei Guo, Gang Wei
Summary: In this study, CuS-PNSs/Ti3C2 nanohybrids were synthesized through the biological modification and self-assembled peptide nanosheets (PNSs)-based biomimetic synthesis. The resulting CuS-PNSs/Ti3C2-based electrochemical biosensor platform showed excellent electrochemical performance for H2O2 detection, with wide detection range and low detection limit. The successful biomimetic synthesis of CuS-PNSs/Ti3C2 hybrid nanomaterials provides a green and friendly strategy for the design and synthesis of functional nanomaterials and also inspires the construction of highly effective electrochemical biosensors for H2O2 detection in different environments.
Review
Nanoscience & Nanotechnology
Hao Kong, Guozheng Yang, Peng He, Danzhu Zhu, Xin Luan, Youyin Xu, Rongqiu Mu, Gang Wei
Summary: The design and regulation of functional peptide sequences are crucial for the self-assembly of peptide molecules and the synthesis of functional peptide-based nanomaterials. This article summarizes recent advances in the bioinspired design and regulation of functional peptide sequences, as well as the applications of biomimetic peptide nanomaterials in various fields. The future development of this promising research topic is also discussed.
Article
Materials Science, Composites
Ping Han, Susu Zhang, Shaokai Hu, Ying Yu, Shaolong Han, Haoyu Wang, Jianfa Wang, Gang Wei, Zheng Gu
Summary: This study demonstrates the innovative concepts of fabricating both gradual rigid-flexible and alternate rigid-flexible structures by altering the grafting sequence of flexible polyethyleneimine and polydopamine. The composites reinforced by the alternate rigid-flexible polymer layer show superior interfacial effects and mechanical properties. This work provides practical and scalable potentials for regulating the structure and functions of CF-reinforced polymer composites by optimal interfacial design.
POLYMER COMPOSITES
(2023)
Article
Polymer Science
Peng He, Minghao Yang, Yu Lei, Lei Guo, Yan Wang, Gang Wei
Summary: Designing functional membranes through the collaboration of multi-dimensional nanomaterials is proposed in this study. A facile and green synthetic strategy is presented, involving graphene oxide (GO), peptides, and silver nanoparticles (AgNPs), for the synthesis of functional hybrid membranes with favorable antibacterial effects. The hybrid membranes are characterized and analyzed, and their excellent antibacterial performances are demonstrated through experiments.
Article
Materials Science, Composites
Haipeng Wu, Hao Wu, Yunxiao Liu, Jie Hu, Ning Zhang, Xiao Wu, Zhen Sun, Gang Wei, Yuwei Chen, Yongxin Duan, Jianming Zhang
Summary: The combination of polymer blends and nanofillers is an effective strategy for creating high-performance polymer alloys. In this study, a one-pot synthesized polyvinyl acetate-modified cellulose nanocrystal (CNCs-PVAc) powder was used to enhance the properties of a PLLA/PBAT blend for 3D filament. The presence of ungrafted PVAc homopolymer improved the dispersion of CNCs in the blend and resulted in an improvement in strength and toughness. Additionally, the nanocomposites showed excellent biodegradability, biocompatibility, and shape-memory properties.
COMPOSITES SCIENCE AND TECHNOLOGY
(2023)
Article
Materials Science, Composites
Shaokai Hu, Ping Han, Susu Zhang, Jianfa Wang, Chao Meng, Gang Wei, Zheng Gu
Summary: In this work, we demonstrate the fabrication of carbon fiber-based composites through the modification of CFs with 2D MXene nanosheets via the layer-by-layer technique. The modified composites exhibit improved interfacial shear strength and surface energy compared to unmodified composites. This study presents a potential strategy to construct hierarchical structure via 2D material modification and shows successful pathway to enhance the interfacial and mechanical performance of composites.
COMPOSITES SCIENCE AND TECHNOLOGY
(2023)
Review
Chemistry, Inorganic & Nuclear
Danzhu Zhu, Hao Kong, Zhengang Sun, Youyin Xu, Ping Han, Yongming Xi, Gang Wei
Summary: Molecular design and biomimetic/bioinspired synthesis provide efficient ways for constructing functional nanomaterials. Peptide-based nanomaterials with desired morphology and functions can be obtained through peptide sequence design, self-assembly regulation, biomimetic synthesis, and hybridization with other nanoscale building blocks. This review highlights the progress in combining peptide self-assembly and biomimetic synthesis to tailor the structure and functions of peptide nanomaterials for biomedical applications. By tuning their structure and functions, peptide-based nanomaterials exhibit enhanced chemical, physical, and biological properties, making them promising candidates for various biomedical applications.
COORDINATION CHEMISTRY REVIEWS
(2023)
Article
Materials Science, Biomaterials
Hao Kong, Jinru Han, Ming Yang, Liangxue Lai, Yabing Sun, Xin Luan, Wenzhi Ren, Aiguo Wu, Gang Wei
Summary: In this study, two-dimensional biocompatible peptide nanosheets (PNSs) were created through molecular self-assembly, which can serve as support matrixes for conjugating gold nanorods (AuNRs) to form high-performance 2D nanomaterials for photothermal conversion in cancer therapy. The results indicate that both PNSs and AuNRs contribute to the improved efficiency of photothermal therapy (PTT) of tumors. The strategies of molecular design and functional tailoring of self-assembled peptide nanomaterials shown in this study are valuable for the synthesis of biomimetic nanomaterials for biomedicine and tissue engineering applications.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Guozheng Yang, Qi Guo, Hao Kong, Xin Luan, Gang Wei
Summary: In this study, TiO2 nanocrystals were mineralized on biomolecules using biomimetic synthesis, resulting in peptide nanofiber (PNF)-TiO2 nanohybrids with controllable structure. These nanohybrids were non-covalently cross-linked with graphene oxide (GO) and graphitic carbon nitride (g-C3N4) to obtain heterostructured aerogels. The obtained hetero-aerogels exhibited good photocatalytic activity and rapid degradation of dyes. The strategy for preparing TiO2-functionalized hetero-aerogels via biomimetic synthesis is green, economical, and efficient, and holds potential applications in various fields.
ENVIRONMENTAL SCIENCE-NANO
(2023)
Review
Chemistry, Multidisciplinary
Youyin Xu, Xin Luan, Peng He, Danzhu Zhu, Rongqiu Mu, Yan Wang, Gang Wei
Summary: Biomimetic synthesis provides guidance for the synthesis of bio-nanomaterials by mimicking natural materials. Behavioral studies of biological surfaces help explore the interactions with various molecules or organisms and inspire the development of biomimetic surfaces. This review focuses on the methodologies of biomimetic synthesis of antifouling interfaces by studying the structure and properties of natural materials, and highlights the importance of biomimetic interfaces with antifouling and low-pollution properties.
Article
Chemistry, Multidisciplinary
Xin Luan, Danzhu Zhu, Peng He, Ping Han, Gang Wei
Summary: In this study, peptide nanosheets functionalized with magnetic nanoparticles were designed and synthesized for the determination and adsorption of Hg2+. The fabricated nanocomposites showed high sensitivity and anti-interference ability in Hg2+ detection, as well as good adsorption efficiency as a sustainable material. This research presents green strategies for preparing functional peptide nanomaterials and inspires potential applications in biological analysis and environmental monitoring.
ENVIRONMENTAL SCIENCE-NANO
(2023)
