A budding yeast's perspective on aging: The shape I'm in

A lifespan-extending form of autophagy employs the vacuole-vacuole fusion machinery

(2014) Fusheng Tang et al.   Autophagy

Absence of superoxide dismutase activity causes nuclear DNA fragmentation during the aging process

(2014) Khandaker Ashfaqul Muid et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inactivation of Yeast Isw2 Chromatin Remodeling Enzyme Mimics Longevity Effect of Calorie Restriction via Induction of Genotoxic Stress Response

(2014) Weiwei Dang et al.   Cell Metabolism

The mystery of aging and rejuvenation—a budding topic

(2014) Thomas Nyström et al.   CURRENT OPINION IN MICROBIOLOGY

The mitochondrial unfolded protein response and increased longevity: Cause, consequence, or correlation?

(2014) Christopher F. Bennett et al.   EXPERIMENTAL GERONTOLOGY

Nar1 deficiency results in shortened lifespan and sensitivity to paraquat that is rescued by increased expression of mitochondrial superoxide dismutase

(2014) Wei Zhao et al.   MECHANISMS OF AGEING AND DEVELOPMENT

The SAGA Histone Deubiquitinase Module Controls Yeast Replicative Lifespan via Sir2 Interaction

(2014) Mark A. McCormick et al.   Cell Reports

Mitochondrial stress signaling in longevity: A new role for mitochondrial function in aging

(2014) Shauna Hill et al.   Redox Biology

Molecular mechanisms underlying genotype-dependent responses to dietary restriction

(2013) Jennifer Schleit et al.   AGING CELL

Cellular Senescence in Yeast Is Regulated by rDNA Noncoding Transcription

(2013) Kimiko Saka et al.   CURRENT BIOLOGY

Fasting or caloric restriction for Healthy Aging

(2013) Stephen Anton et al.   EXPERIMENTAL GERONTOLOGY

Inheritance of the fittest mitochondria in yeast

(2013) Jason D. Vevea et al.   TRENDS IN CELL BIOLOGY

A Natural Polymorphism in rDNA Replication Origins Links Origin Activation with Calorie Restriction and Lifespan

(2013) Elizabeth X. Kwan et al.   PLoS Genetics

Genetics of Longevity in Model Organisms: Debates and Paradigm Shifts

(2012) David Gems et al.   Annual Review of Physiology

Osh6 overexpression extends the lifespan of yeast by increasing vacuole fusion

(2012) Senetibeb Gebre et al.   CELL CYCLE

Yeast hypertrophy: cause or consequence of aging? Reply to Bilinski et al

(2012) Austen R.D. Ganley et al.   FEMS YEAST RESEARCH

Hypertrophy and senescence factors in yeast aging. A reply to Bilinski et al.

(2012) Matt Kaeberlein   FEMS YEAST RESEARCH

A growing role for hypertrophy in senescence

(2012) Jill Wright et al.   FEMS YEAST RESEARCH

Natural genetic variation in yeast longevity

(2012) S. W. Stumpferl et al.   GENOME RESEARCH

Isonicotinamide Enhances Sir2 Protein-mediated Silencing and Longevity in Yeast by Raising Intracellular NAD+Concentration

(2012) Julie M. McClure et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Molecular chaperones and stress-inducible protein-sorting factors coordinate the spatiotemporal distribution of protein aggregates

(2012) Liliana Malinovska et al.   MOLECULAR BIOLOGY OF THE CELL

Impact of caloric restriction on health and survival in rhesus monkeys from the NIA study

(2012) Julie A. Mattison et al.   NATURE

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

An early age increase in vacuolar pH limits mitochondrial function and lifespan in yeast

(2012) Adam L. Hughes et al.   NATURE

Whole lifespan microscopic observation of budding yeast aging through a microfluidic dissection platform

(2012) S. S. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Confinement to Organelle-Associated Inclusion Structures Mediates Asymmetric Inheritance of Aggregated Protein in Budding Yeast

(2012) Rachel Spokoini et al.   Cell Reports

Sir2 deletion prevents lifespan extension in 32 long-lived mutants

(2011) Joe R. Delaney et al.   AGING CELL

Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast

(2011) José Ricardo McFaline-Figueroa et al.   AGING CELL

Quantitative evidence for early life fitness defects from 32 longevity-associated alleles in yeast

(2011) Joe R. Delaney et al.   CELL CYCLE

Cell size and growth rate are major determinants of replicative lifespan

(2011) Jingye Yang et al.   CELL CYCLE

Artificial tethering to nuclear pores promotes partitioning of extrachromosomal DNA during yeast asymmetric cell division

(2011) Anton Khmelinskii et al.   CURRENT BIOLOGY

Hypertrophy hypothesis as an alternative explanation of the phenomenon of replicative aging of yeast

(2011) Tomasz Biliński et al.   FEMS YEAST RESEARCH

Changes in reactive oxygen species begin early during replicative aging of Saccharomyces cerevisiae cells

(2011) Yuen T. Lam et al.   FREE RADICAL BIOLOGY AND MEDICINE

Extending life span by increasing oxidative stress

(2011) Michael Ristow et al.   FREE RADICAL BIOLOGY AND MEDICINE

Life Span Extension and H2O2 Resistance Elicited by Caloric Restriction Require the Peroxiredoxin Tsa1 in Saccharomyces cerevisiae

(2011) Mikael Molin et al.   MOLECULAR CELL

Regulation of Caenorhabditis elegans lifespan by sir-2.1 transgenes

(2011) Mohan Viswanathan et al.   NATURE

Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila

(2011) Camilla Burnett et al.   NATURE

Fasting vs dietary restriction in cellular protection and cancer treatment: from model organisms to patients

(2011) C Lee et al.   ONCOGENE

Gametogenesis Eliminates Age-Induced Cellular Damage and Resets Life Span in Yeast

(2011) E. Unal et al.   SCIENCE

Elevated Proteasome Capacity Extends Replicative Lifespan in Saccharomyces cerevisiae

(2011) Undine Kruegel et al.   PLoS Genetics

The Evolutionarily Conserved Longevity Determinants HCF-1 and SIR-2.1/SIRT1 Collaborate to Regulate DAF-16/FOXO

(2011) Gizem Rizki et al.   PLoS Genetics

Mitochondria-mediated hormetic response in life span extension of calorie-restricted Saccharomyces cerevisiae

(2010) Praveen Kumar Sharma et al.   AGE

Dietary restriction and aging, 2009

(2010) Subhash D. Katewa et al.   AGING CELL

The Polarisome Is Required for Segregation and Retrograde Transport of Protein Aggregates

(2010) Beidong Liu et al.   CELL

Nuclear Geometry and Rapid Mitosis Ensure Asymmetric Episome Segregation in Yeast

(2010) Lutz R. Gehlen et al.   CURRENT BIOLOGY

How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)

(2010) Michael Ristow et al.   EXPERIMENTAL GERONTOLOGY

The lipophilic antioxidants α-tocopherol and coenzyme Q10 reduce the replicative lifespan of Saccharomyces cerevisiae

(2010) Yuen Ting Lam et al.   FREE RADICAL BIOLOGY AND MEDICINE

Segregation of yeast nuclear pores

(2010) Anton Khmelinskii et al.   NATURE

Lessons on longevity from budding yeast

(2010) Matt Kaeberlein   NATURE

A Mitochondrial Superoxide Signal Triggers Increased Longevity in Caenorhabditis elegans

(2010) Wen Yang et al.   PLOS BIOLOGY

Calorie restriction effects on silencing and recombination at the yeast rDNA

(2009) Daniel L. Smith Jr et al.   AGING CELL

Calorie restriction reduces rDNA recombination independently of rDNA silencing

(2009) Michèle Riesen et al.   AGING CELL

Genetic variation in the murine lifespan response to dietary restriction: from life extension to life shortening

(2009) Chen-Yu Liao et al.   AGING CELL

Is the oxidative stress theory of aging dead?

(2009) Viviana I. Pérez et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Caloric Restriction Delays Disease Onset and Mortality in Rhesus Monkeys

(2009) R. J. Colman et al.   SCIENCE

Deletion of the Mitochondrial Superoxide Dismutase sod-2 Extends Lifespan in Caenorhabditis elegans

(2009) Jeremy M. Van Raamsdonk et al.   PLoS Genetics

Prohibitin function within mitochondria: Essential roles for cell proliferation and cristae morphogenesis

(2008) Carsten Merkwirth et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Misfolded proteins partition between two distinct quality control compartments

(2008) Daniel Kaganovich et al.   NATURE

Selective benefits of damage partitioning in unicellular systems and its effects on aging

(2008) N. Erjavec et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA