Sulforaphane attenuates the development of atherosclerosis and improves endothelial dysfunction in hypercholesterolemic rabbits

Increasing HDL levels by inhibiting cholesteryl ester transfer protein activity in rabbits with hindlimb ischemia is associated with increased angiogenesis

(2015) Ben J. Wu et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway

(2014) Palanisamy Nallasamy et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Sulforaphane Attenuation of Type 2 Diabetes-Induced Aortic Damage Was Associated with the Upregulation of Nrf2 Expression and Function

(2014) Yonggang Wang et al.   Oxidative Medicine and Cellular Longevity

Isothiocyanates protect against oxidized LDL-induced endothelial dysfunction by upregulating Nrf2-dependent antioxidation and suppressing NFκB activation

(2013) Chin-Shiu Huang et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Sulforaphane inhibits restenosis by suppressing inflammation and the proliferation of vascular smooth muscle cells

(2012) Jin-Sook Kwon et al.   ATHEROSCLEROSIS

Cruciferous vegetable consumption is associated with a reduced risk of total and cardiovascular disease mortality

(2011) Xianglan Zhang et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Regulation of the Keap1/Nrf2 system by chemopreventive sulforaphane: implications of posttranslational modifications

(2011) Young-Sam Keum   Annals of the New York Academy of Sciences

Allyl isothiocyanate as a potential inducer of paraoxonase-1 - studies in cultured hepatocytes and in mice

(2011) Charlotte Schrader et al.   IUBMB LIFE

Anti-inflammatory potential of allyl-isothiocyanate - role of Nrf2, NF-κB and microRNA-155

(2011) Anika Eva Wagner et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Sulforaphane suppresses vascular adhesion molecule-1 expression in TNF-α-stimulated mouse vascular smooth muscle cells: Involvement of the MAPK, NF-κB and AP-1 signaling pathways

(2011) Ji-Yun Kim et al.   VASCULAR PHARMACOLOGY

Sulforaphane inhibits endothelial lipase expression through NF-κB in endothelial cells

(2010) Annukka M. Kivelä et al.   ATHEROSCLEROSIS

α-Tocopherol Is Ineffective in Preventing the Decomposition of Preformed Lipid Peroxides and May Promote the Accumulation of Toxic Aldehydes: A Potential Explanation for the Failure of Antioxidants to Affect Human Atherosclerosis

(2009) Achuthan Raghavamenon et al.   ANTIOXIDANTS & REDOX SIGNALING

Sulforaphane inhibits TNF-α-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cells

(2009) Xi-Lin Chen et al.   INFLAMMATION RESEARCH

Active NF-E2-related Factor (Nrf2) Contributes to Keep Endothelial NO Synthase (eNOS) in the Coupled State

(2009) Elke H. Heiss et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antioxidants in Cardiovascular Health and Disease: Key Lessons from Epidemiologic Studies

(2008) Bradley J. Willcox et al.   AMERICAN JOURNAL OF CARDIOLOGY

Potent Induction of Total Cellular and Mitochondrial Antioxidants and Phase 2 Enzymes by Cruciferous Sulforaphane in Rat Aortic Smooth Muscle Cells: Cytoprotection Against Oxidative and Electrophilic Stress

(2008) Hong Zhu et al.   Cardiovascular Toxicology

Is there a role for supplemented antioxidants in the prevention of atherosclerosis?

(2008) Niki Katsiki et al.   CLINICAL NUTRITION

Activation of NF-E2-Related Factor-2 Reverses Biochemical Dysfunction of Endothelial Cells Induced by Hyperglycemia Linked to Vascular Disease

(2008) M. Xue et al.   DIABETES

Role of the Histone H3 Lysine 4 Methyltransferase, SET7/9, in the Regulation of NF-κB-dependent Inflammatory Genes

(2008) Yan Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-κB is dependent upon glutathione depletion in endothelial cells

(2008) Yen-Chin Liu et al.   VASCULAR PHARMACOLOGY