Jianpi Huayu Decoction Inhibits Proliferation in Human Colorectal Cancer Cells (SW480) by Inducing G0/G1-Phase Cell Cycle Arrest and Apoptosis

The investigational Aurora kinase A inhibitor alisertib (MLN8237) induces cell cycle G2/M arrest, apoptosis, and autophagy via p38 MAPK and Akt/mTOR signaling pathways in human breast cancer cells

(2015) Shu-Feng Zhou et al.   Drug Design Development and Therapy

Aloperine induces G2/M phase cell cycle arrest and apoptosis in HCT116 human colon cancer cells

(2014) LI ZHANG et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Herbal medicine Guan Chang Fu Fang enhances 5-fluorouracil cytotoxicity and affects drug-associated genes in human colorectal carcinoma cells

(2014) CHEN YU et al.   Oncology Letters

Highlights of the Latest Advances in Research on CDK Inhibitors

(2014) Jonas Cicenas et al.   Cancers

Cdks, cyclins and CKIs: roles beyond cell cycle regulation

(2013) S. Lim et al.   DEVELOPMENT

Oligosaccharide from apple induces apoptosis and cell cycle arrest in HT29 human colon cancer cells

(2013) Qian Li et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Scutellaria barbata D. Don induces G1/S arrest via modulation of p53 and Akt pathways in human colon carcinoma cells

(2013) LIHUI WEI et al.   ONCOLOGY REPORTS

Drug discovery enters a new era with multi-target intervention strategy

(2012) Xiao-ying Tian et al.   Chinese Journal of Integrative Medicine

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

6,7,4'-Trihydroxyisoflavone inhibits HCT-116 human colon cancer cell proliferation by targeting CDK1 and CDK2

(2011) D. E. Lee et al.   CARCINOGENESIS

Control of cell cycle progression by phosphorylation of cyclin-dependent kinase (CDK) substrates

(2010) Randy Suryadinata et al.   BIOSCIENCE REPORTS

5-Fluorouracil and its active metabolite FdUMP cause DNA damage in human SW620 colon adenocarcinoma cell line

(2009) Renata Matuo et al.   JOURNAL OF APPLIED TOXICOLOGY

Control of mitochondrial apoptosis by the Bcl-2 family

(2009) J. K. Brunelle et al.   JOURNAL OF CELL SCIENCE

Apoptosis and cancer: mutations within caspase genes

(2009) S Ghavami et al.   JOURNAL OF MEDICAL GENETICS

Natural products in drug discovery

(2008) A HARVEY   DRUG DISCOVERY TODAY

Global control of cell-cycle transcription by coupled CDK and network oscillators

(2008) David A. Orlando et al.   NATURE

Expansion and evolution of cell death programmes

(2008) Alexei Degterev et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY