High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice
出版年份 2015 全文链接
标题
High folic acid consumption leads to pseudo-MTHFR deficiency, altered lipid metabolism, and liver injury in mice
作者
关键词
-
出版物
AMERICAN JOURNAL OF CLINICAL NUTRITION
Volume 101, Issue 3, Pages 646-658
出版商
Oxford University Press (OUP)
发表日期
2015-01-08
DOI
10.3945/ajcn.114.086603
参考文献
相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。- Is folic acid good for everyone?
- (2018) A David Smith et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Circulating folic acid in plasma: relation to folic acid fortification
- (2018) Renee D Kalmbach et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Novel insights on interactions between folate and lipid metabolism
- (2013) Robin P. da Silva et al. BIOFACTORS
- Metformin Retards Aging in C. elegans by Altering Microbial Folate and Methionine Metabolism
- (2013) Filipe Cabreiro et al. CELL
- Role of adipose triglyceride lipase (PNPLA2) in protection from hepatic inflammation in mouse models of steatohepatitis and endotoxemia
- (2013) Pooja Jha et al. HEPATOLOGY
- A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development
- (2013) K.E. Christensen et al. HUMAN MOLECULAR GENETICS
- Moderately high intake of folic acid has a negative impact on mouse embryonic development
- (2012) Leonie G. Mikael et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Primer-BLAST: A tool to design target-specific primers for polymerase chain reaction
- (2012) Jian Ye et al. BMC BIOINFORMATICS
- Dietary folate does not significantly affect the intestinal microbiome, inflammation or tumorigenesis in azoxymethane–dextran sodium sulphate-treated mice
- (2012) Amanda J. MacFarlane et al. BRITISH JOURNAL OF NUTRITION
- Maternal choline intake alters the epigenetic state of fetal cortisol-regulating genes in humans
- (2012) Xinyin Jiang et al. FASEB JOURNAL
- Estimation of Trends in Serum and RBC Folate in the U.S. Population from Pre- to Postfortification Using Assay-Adjusted Data from the NHANES 1988–2010
- (2012) Christine M. Pfeiffer et al. JOURNAL OF NUTRITION
- Differential gene expression and methylation in the retinoid/PPARA pathway and of tumor suppressors may modify intestinal tumorigenesis induced by low folate in mice
- (2012) Daniel Leclerc et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Cholesterol metabolism and the pathogenesis of non-alcoholic steatohepatitis
- (2012) Giovanni Musso et al. PROGRESS IN LIPID RESEARCH
- MTHFR 677C→T genotype is associated with folate and homocysteine concentrations in a large, population-based, double-blind trial of folic acid supplementation
- (2011) Krista S Crider et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- A Conserved SREBP-1/Phosphatidylcholine Feedback Circuit Regulates Lipogenesis in Metazoans
- (2011) Amy K. Walker et al. CELL
- Methionine and protein metabolism in non-alcoholic steatohepatitis: evidence for lower rate of transmethylation of methionine
- (2011) Satish C. Kalhan et al. CLINICAL SCIENCE
- Methionine adenosyltransferase 1A gene deletion disrupts hepatic very low-density lipoprotein assembly in mice
- (2011) Ainara Cano et al. HEPATOLOGY
- ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1
- (2011) Guenter Haemmerle et al. NATURE MEDICINE
- Human Fatty Liver Disease: Old Questions and New Insights
- (2011) J. C. Cohen et al. SCIENCE
- Folic Acid Food Fortification—Its History, Effect, Concerns, and Future Directions
- (2011) Krista S. Crider et al. Nutrients
- MTHFR C677T genotype influences the isotopic enrichment of one-carbon metabolites in folate-compromised men consuming d9-choline
- (2010) Jian Yan et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Circulating unmetabolized folic acid and 5-methyltetrahydrofolate in relation to anemia, macrocytosis, and cognitive test performance in American seniors
- (2010) Martha Savaria Morris et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Total folate and folic acid intakes from foods and dietary supplements of US children aged 1–13 y
- (2010) Regan L Bailey et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Contributions of enriched cereal-grain products, ready-to-eat cereals, and supplements to folic acid and vitamin B-12 usual intake and folate and vitamin B-12 status in US children: National Health and Nutrition Examination Survey (NHANES), 2003–2006
- (2010) Lorraine F Yeung et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Steatosis in Mice Is Associated with Gender, Folate Intake, and Expression of Genes of One-Carbon Metabolism
- (2010) Karen E. Christensen et al. JOURNAL OF NUTRITION
- Proliferative and Nonproliferative Lesions of the Rat and Mouse Hepatobiliary System
- (2010) Bob Thoolen et al. TOXICOLOGIC PATHOLOGY
- Total folate and folic acid intake from foods and dietary supplements in the United States: 2003–2006
- (2009) Regan L Bailey et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Intestinal Neoplasia Induced by Low Dietary Folate Is Associated with Altered Tumor Expression Profiles and Decreased Apoptosis in Mouse Normal Intestine
- (2009) David Garcia-Crespo et al. JOURNAL OF NUTRITION
- The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores
- (2009) Rafael A Irizarry et al. NATURE GENETICS
- Trends in the postfortification prevalence of spina bifida and anencephaly in the United States
- (2008) Sheree L. Boulet et al. BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY
- Folate intake and the MTHFR C677T genotype influence choline status in young Mexican American women
- (2007) Christian M. Abratte et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started