Article
Engineering, Aerospace
Rao Hamza Ali, Amir Kanan Kashefi, Alice C. Gorman, Justin St. P. Walsh, Erik J. Linstead
Summary: We have developed and applied a deep learning-based computer vision pipeline to identify crew members in archival photos taken on the International Space Station. Our approach can accurately tag a large number of images from public and private repositories, even when crew faces are partially obscured. Using the results of our pipeline, we conducted a network analysis of the crew, providing novel insights into their social interactions during missions.
Article
Multidisciplinary Sciences
Deborah CNavarro C. Morales, Olga Kuldavletova, Gaelle Quarck, Pierre Denise, Gilles Clement
Summary: The mental representation of space is altered in orbit, leading to changes in the perception of time. During a 6-8-month spaceflight, astronauts overestimate 1-minute intervals and underestimate intervals of hours. However, they accurately estimate the number of days since certain events.
Article
Multidisciplinary Sciences
Alan Feiveson, Kerry George, Mark Shavers, Maria Moreno-Villanueva, Ye Zhang, Adriana Babiak-Vazquez, Brian Crucian, Edward Semones, Honglu Wu
Summary: The study investigates the impact of space radiation on astronauts' chromosomes and suggests that individual radiosensitivity may affect post-flight chromosome aberration rates. Additionally, both background CAR and radiosensitivity tend to increase with age.
SCIENTIFIC REPORTS
(2021)
Article
Sport Sciences
Pierre Bourdier, Alexandre Zahariev, Dale A. Schoeller, Isabelle Chery, Elisa Le Roux, Cecile Thevenot, Alain Maillet, Mael Garnotel, Guillemette Gauquelin-Koch, Audrey Bergouignan, Stephane Blanc, Chantal Simon
Summary: This study investigated the energy balance and body composition changes in astronauts during 6-month missions on the International Space Station. The results showed that ground fitness and inflight overall physical activity are associated with spaceflight-induced energy expenditure and body composition changes. New instruments are needed to measure real-time individual changes in inflight energy balance components.
Article
Dermatology
Xuefeng Gu, Yuru Han, Yue Shao, Wenhao Ma, Zeguo Shao, Guoqing Wan, Changlian Lu, Shuo Shi, Wenli Lu
Summary: Through bioinformatics analysis, it was found that the space environment affects skin keratinocyte differentiation, leading to skin barrier damage and inflammatory responses, but this effect is decreased after return to Earth. Among 10 International Space Station astronauts studied, 311 genes increased in expression after space entry and decreased after return to Earth. Genes with this expression pattern were associated with skin development, keratinocyte differentiation, and cornification. We found that these hub skin-related genes are involved in skin barrier damage and inflammatory responses.
CLINICAL AND EXPERIMENTAL DERMATOLOGY
(2023)
Article
Physics, Multidisciplinary
Yipan Guo, Fazhi Yan, Meihua Fang, Zhao Zhang, Wei Cheng, Bing Guo
Summary: With the development of China's crewed space mission, the paper presents a simulation of radiation doses experienced by a Chinese female voxel phantom on board the Chinese Space Station. The study discusses the absorbed dose, equivalent dose, and effective dose of the voxel phantom and its critical organs under different levels of shielding. The research assesses the risk of space-radiation exposure by comparing these doses with current risk limits in China and NASA figures for female astronauts, providing guidance for optimizing radiation protection in manned space missions.
Article
Thermodynamics
A. Sielaff, D. Mangini, O. Kabov, M. Q. Raza, A. I. Garivalis, M. Zupancic, S. Dehaeck, S. Evgenidis, C. Jacobs, D. Van Hoof, O. Oikonomidou, X. Zabulis, P. Karamaounas, A. Bender, F. Ronshin, M. Schinnerl, J. Sebilleau, C. Colin, P. Di Marco, T. Karapantsios, I. Golobic, A. Rednikov, P. Colinet, P. Stephan, L. Tadrist
Summary: This publication lays the foundation for the description of the Multiscale Boiling Experiment conducted on the International Space Station. The experiment investigates two-phase heat transfer during boiling processes by selectively igniting bubbles on a heated substrate using a short laser pulse. The study is significant for understanding the phenomena and has generated over 3000 datasets over an 11-month measurement period.
APPLIED THERMAL ENGINEERING
(2022)
Article
Biochemistry & Molecular Biology
Alicia L. Veliz, Lana Mamoun, Lorelei Hughes, Richard Vega, Bailey Holmes, Andrea Monteon, Jillian Bray, Michael J. Pecaut, Mary Kearns-Jonker
Summary: This study focuses on the transcriptomic changes in the hearts of female C57BL/6J mice flown on the International Space Station (ISS) for 30 days. RNA sequencing revealed that 1147 transcripts were significantly regulated after spaceflight, and the MAPK, PI3K-Akt, and GPCR signaling pathways were predicted to be activated. Transcripts related to cytoskeleton breakdown and organization were upregulated, but no significant change in the expression of extracellular matrix (ECM) components or oxidative stress pathway-associated transcripts occurred. Our findings suggest an absence of cellular senescence and an adaptive response to long-term spaceflight in the cardiovascular transcriptome.
Article
Microbiology
Charles S. Cockell, Rosa Santomartino, Kai Finster, Annemiek C. Waajen, Natasha Nicholson, Claire-Marie Loudon, Lorna J. Eades, Ralf Moeller, Petra Rettberg, Felix M. Fuchs, Rob Van Houdt, Natalie Leys, Ilse Coninx, Jason Hatton, Luca Parmitano, Jutta Krause, Andrea Koehler, Nicol Caplin, Lobke Zuijderduijn, Alessandro Mariani, Stefano Pellari, Fabrizio Carubia, Giacomo Luciani, Michele Balsamo, Valfredo Zolesi, Jon Ochoa, Pia Sen, James A. J. Watt, Jeannine Doswald-Winkler, Magdalena Herova, Bernd Rattenbacher, Jennifer Wadsworth, R. Craig Everroad, Rene Demets
Summary: The study found that under different gravity conditions, Sphingomonas desiccabilis and Bacillus subtilis enhanced the leaching of vanadium by 184.92% to 283.22% compared to sterile controls. Gravity did not significantly affect the mean leaching rate, demonstrating the potential for biomining on Solar System objects.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Microbiology
Adriana Blachowicz, Jillian Romsdahl, Abby J. Chiang, Sawyer Masonjones, Markus Kalkum, Jason E. Stajich, Tamas Torok, Clay C. C. Wang, Kasthuri Venkateswaran
Summary: This study reports the genomic, proteomic, and metabolomic alterations in Aspergillus niger strain JSC-093350089 grown in a controlled experiment aboard the International Space Station (ISS). Results show that microgravity and enhanced irradiation triggered non-synonymous point mutations in specific regions of the genome, altered protein abundance, and changed the metabolite composition.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Chemistry, Physical
William Delmas, Samuel Erickson, Jorge Arteaga, Mark Woodall, Michael Scheibner, Timothy S. Krause, Kyle Crowley, Kaitlyn T. VanSant, Joseph M. Luther, Jennifer N. Williams, Jeremiah McNatt, Timothy J. Peshek, Lyndsey McMillon-Brown, Sayantani Ghosh
Summary: Metal halide perovskites (MHPs) have high power conversion efficiency and excellent stability in space, making them suitable for aerospace applications.
ADVANCED ENERGY MATERIALS
(2023)
Article
Forestry
Henri Gouin
Summary: Experiments have shown that the Moon's actions can cause oscillations in plant leaves, possibly due to parametric resonance induced by short period microgravitational forces. The magnitude of these instabilities depends on the distances between the Moon, the Sun, and the Earth, and they are analogous to phenomena occurring during ocean tides but less spectacular.
Article
Clinical Neurology
Christopher W. Jones, Mathias Basner, Daniel J. Mollicone, Christopher M. Mott, David F. Dinges
Summary: Sleep deficiency in spaceflight has adverse effects on neurobehavioral functions of astronauts, including reduced psychomotor response speed, increased stress, and higher workload. Longer sleep durations have beneficial effects on astronaut neurobehavioral functions.
Article
Biology
Agnieszka Brojakowska, Anupreet Kour, Mark Charles Thel, Eunbee Park, Malik Bisserier, Venkata Naga Srikanth Garikipati, Lahouaria Hadri, Paul J. Mills, Kenneth Walsh, David A. Goukassian
Summary: Deep targeted DNA sequencing of peripheral blood mononuclear cells from 14 astronauts who flew Shuttle missions between 1998-2001 identified non-silent mutations, predominantly in TP53 and DNMT3A. Further investigation is needed to address health risks in astronauts as deep space and commercial spaceflights become more common. Studies have also shown associations between clonal expansion of hematopoietic cells and hematopoietic malignancies and cardiometabolic disease.
COMMUNICATIONS BIOLOGY
(2022)
Article
Microbiology
Rachita K. Kumar, Nitin Kumar Singh, Sanjaay Balakrishnan, Ceth W. Parker, Karthik Raman, Kasthuri Venkateswaran
Summary: This study predicts possible metabolic interactions in the ISS microbiome using a computational approach and sheds further light on its organization. The results show beneficial interactions between Klebsiella pneumoniae and Pantoea genus, and parasitic and amensalistic interactions between Klebsiella pneumoniae and Aspergillus and Penicillium species. Klebsiella pneumoniae has positive effects on the survival of other microorganisms, but may also have negative interactions with potential pathogens.
Meeting Abstract
Psychology, Developmental
Roseanne Mauch, Crystal Natvig, Irene Blair, Mark Laudenslager
JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
(2020)
Article
Oncology
Nicole A. Pensak, Alaina L. Carr, Jacqueline Jones, Susan K. Mikulich-Gilbertson, Jean S. Kutner, Kristin Kilbourn, Timothy S. Sannes, Benjamin B. Brewer, Elissa Kolva, Tanisha Joshi, Mark L. Laudenslager
Summary: This study examined the usage rates and efficacy estimates of a mobile intervention called Pep-Pal in helping caregivers of patients with advanced cancer manage distress. Results showed that participants in the Pep-Pal intervention experienced greater reductions in perceived stress, better ability to learn and use stress management skills, and improved sexual function (for women).
Article
Oncology
Scott G. Ravyts, Timothy S. Sannes, Joseph M. Dzierzewski, Eric S. Zhou, Benjamin W. Brewer, Crystal Natvig, Mark L. Laudenslager
Summary: This study suggests that psychosocial interventions for HSCT caregivers can help alleviate psychological distress, particularly among caregivers with poor sleep quality. Baseline sleep quality may moderate the effect of psychosocial interventions on depression outcomes, while only sleep quality and onset latency may moderate the effect on anxiety outcomes.
Article
Oncology
Crystal Natvig, Susan K. Mikulich-Gilbertson, Mark L. Laudenslager, Cathy J. Bradley
Summary: This study found that caregivers of Allo-HSCT patients who reduced their work hours after resuming caregiving duties had higher levels of depression and anxiety compared to caregivers who did not reduce work hours. Further investigation is needed to understand the underlying causes of distress in caregivers who reduce work hours while caregiving.
JOURNAL OF CANCER SURVIVORSHIP
(2022)
Article
Gerontology
Chad Danyluck, Irene V. Blair, Spero M. Manson, Mark L. Laudenslager, Stacie L. Daugherty, Luohua Jiang, Elizabeth Brondolo
Summary: The study found that discrimination was more strongly associated with depressive symptoms among younger adult urban American Indians and Alaska Natives. This highlights the importance of considering life course perspectives, and further longitudinal and qualitative research is needed to understand why discrimination may have a stronger effect on mental health for younger AI/AN.
JOURNAL OF AGING AND HEALTH
(2021)
Article
Environmental Sciences
Kelly Cunningham, Thomas G. Hinton, Jared J. Luxton, Aryn Bordman, Kei Okuda, Lynn E. Taylor, Josh Hayes, Hannah C. Gerke, Sarah M. Chinn, Donovan Anderson, Mark L. Laudenslager, Tsugiko Takase, Yui Nemoto, Hiroko Ishiniwa, James C. Beasley, Susan M. Bailey
Summary: The health effects of chronic low-dose, low-dose rate radiation exposure on wildlife in Fukushima, Japan were studied using biomarkers of DNA damage and stress in wild boar and snakes. No significant relationship was found between chromosome frequencies or telomere length and radiation dose, although cortisol levels were associated with higher dose rates. Overall, the results suggest that the wildlife studied did not experience significant adverse health effects despite chronic exposure to radiation.
ENVIRONMENT INTERNATIONAL
(2021)
Article
Health Care Sciences & Services
Timothy S. Sannes, Krista W. Ranby, Miryam Yusufov, Benjamin W. Brewer, Jamie M. Jacobs, Stephanie Callan, Gillian R. Ulrich, Nicole A. Pensak, Crystal Natvig, Mark L. Laudenslager
Summary: This study examined the well-being of family caregivers of Hematopoietic stem cell transplantation (HSCT) patients during the treatment process and found a significant correlation between patient quality of life and caregiver depression. The results suggest a significant yet nuanced interdependence between patients and caregivers, providing potential treatment targets for patients and their families.
HEALTH AND QUALITY OF LIFE OUTCOMES
(2022)
Article
Psychology, Multidisciplinary
Chad Danyluck, Irene Blair, Spero M. Manson, Mark L. Laudenslager, Stacie L. Daugherty, Elizabeth Brondolo
Summary: This study investigated the association between interpersonal discrimination and sleep impairment in urban AI/AN. The results showed that lifetime discrimination was associated with sleep impairment, while past-week discrimination was not. Furthermore, education was found to buffer the effects of discrimination on sleep, but income was not.
ANNALS OF BEHAVIORAL MEDICINE
(2022)
Article
Public, Environmental & Occupational Health
Neda Senehi, Marjo Flykt, Zeynep Biringen, Mark L. Laudenslager, Sarah Enos Watamura, Brady A. Garrett, Terrence K. Kominsky, Hannah E. Wurster, Michelle Sarche
Summary: Positive parent-child relationship quality is crucial for buffering children from the effects of stress on development, highlighting the importance of interventions targeting this area. The study reveals a moderating role of parent-child relationship quality in the intergenerational association between parental adverse childhood experiences and young children's hair cortisol concentrations, emphasizing the need for support in building emotionally available relationships between parents and children.
PREVENTION SCIENCE
(2021)
Article
Public, Environmental & Occupational Health
Rachael E. Wagner, Melissa Jonson-Reid, Brett Drake, Patricia L. Kohl, Laura Pons, Yi Zhang, Robert T. Fitzgerald, Mark L. Laudenslager, John N. Constantino
Summary: This study identified parameters of toxic stress in low-income infants and toddlers and found low associations between maternal depression, child abuse and neglect, and caregiver emotional unavailability with adverse child behavioral outcomes. Despite high poverty and child maltreatment rates, children in this sample did not have higher levels of behavior problems compared to the general population. The pilot intervention did not significantly reduce adverse behavioral outcomes or child abuse and neglect. The study highlights the importance of comprehensive understanding of risk and buffering effects, and the need for further research on resilience in early childhood.
PREVENTION SCIENCE
(2022)
Meeting Abstract
Psychiatry
Timothy S. Sannes, Crystal L. Natvig, Mark L. Laudenslager
PSYCHOSOMATIC MEDICINE
(2021)
Article
Ethnic Studies
Irene Blair, Chad Danyluck, Charles M. Judd, Spero M. Manson, Mark L. Laudenslager, Stacie L. Daugherty, Erin L. Ratliff, Jacqueline A. Gardner, Elizabeth Brondolo
Summary: This study provides strong evidence that the PEDQ-CVB behaves consistently across American Indians and other underrepresented ethnic/racial groups. The questionnaire demonstrated measurement invariance and validity in American Indians, showing significant associations with depressive symptoms and physical limitations.
CULTURAL DIVERSITY & ETHNIC MINORITY PSYCHOLOGY
(2021)
Meeting Abstract
Psychiatry
Irene V. Blair, Stacie L. Daugherty, Elizabeth Brondolo, Spero M. Manson, Edward P. Havranek, John F. Steiner, Chad Danyluck, Joshua Correll, Mark L. Laudenslager
PSYCHOSOMATIC MEDICINE
(2020)
Meeting Abstract
Psychiatry
Chad Danyluck, Irene V. Blair, Mark L. Laudenslager, Stacie L. Daugherty, Spero M. Manson, Joshua Correll, Elizabeth Brondolo
PSYCHOSOMATIC MEDICINE
(2020)
Article
Public, Environmental & Occupational Health
Pamela M. Murnane, Joshua D. Miller, Emily L. Tuthill, Shalean M. Collins, Torsten B. Neilands, Maricianah Onono, Craig R. Cohen, Sheri D. Weiser, Mark L. Laudenslager, Sera L. Young
