期刊
JOURNAL OF THE PEDIATRIC INFECTIOUS DISEASES SOCIETY
卷 6, 期 3, 页码 E123-E133出版社
OXFORD UNIV PRESS
DOI: 10.1093/jpids/pix059
关键词
aspergillosis; Candida meningoencephalitis; CNS; cryptococcosis; fungal infections; mucormycosis
资金
- Save Our Sick (SOS) Kids Foundation
- Henry Schueler Foundation
Although uncommon in children, fungal infections of the central nervous system can be devastating and difficult to treat. A better understanding of basic mycologic, immunologic, and pharmacologic processes has led to important advances in the diagnosis and management of these diseases, but their mortality rates remain unacceptably high. In this focused review, we examine the epidemiology and clinical features of the most common fungal pathogens of the central nervous system in children and explore recent advances in diagnosis and antifungal therapy.
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