Article
Chemistry, Analytical
Jia Sun, Aili Feng, Xia Wu, Xiaowen Che, Weizhi Zhou
Summary: A composite fluorescent nanoprobe based on metal enhanced fluorescence effect of gelatin-coated silver nanoparticles was developed for selective and sensitive detection of dopamine. The probe showed a low detection limit and good selectivity, making it a promising approach for dopamine detection in human serum samples.
Article
Materials Science, Multidisciplinary
Jiajun Chen, Zhinan Fan, Chi Zhang, Huatian Duan, Li-Juan Fan
Summary: A fluorescence sensing system based on an amphiphilic conjugated polyelectrolyte was successfully constructed to detect neomycin, a common antibiotic in the environment and food. The system showed excellent sensing performance towards neomycin at a neutral pH value, with a blue-to-green fluorescence color change observed by the naked eye. The mechanism study confirmed that polymer aggregation played a crucial role in inducing the visually fluorescent color change.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Engineering, Biomedical
Mengsi Wu, Chao Chen, Zhiyong Liu, Jia Tian, Weian Zhang
Summary: Photodynamic therapy is an effective antibacterial treatment, but it often suffers from oxygen limitation. This study developed an oxygen-tunable nanoplatform FBC-F, which showed enhanced antibacterial efficacy in vitro and in vivo.
ACTA BIOMATERIALIA
(2022)
Article
Chemistry, Physical
Marisa Hoffmann, Daniel Schletz, Anja Maria Steiner, Daniel Wolf, Martin Mayer, Andreas Fery
Summary: The synthesis of conjugated polymer-gold-silver hybrid colloids allows for the utilization of plasmonic energy in real-world applications by using silver as the central plasmonic material and prolonging the internal relaxation through a heterojunction with a conductive polymer shell.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Biochemistry & Molecular Biology
Lewis Rolband, Liam Yourston, Morgan Chandler, Damian Beasock, Leyla Danai, Seraphim Kozlov, Nolan Marshall, Oleg Shevchenko, Alexey Krasnoslobodtsev, Kirill A. Afonin
Summary: This study combines atomically precise metal nanoclusters with nucleic acid nanotechnology to create DNA-templated silver nanoclusters with reproducible fluorescent properties and antibacterial activity. Additionally, the use of cytosine-rich single-stranded DNA oligonucleotides improves stability, modulates antibacterial properties, and enhances the quality of observed fluorescent signals of the silver nanoclusters. The research characterizes the sequence-specific fluorescence and composition of four representative DNA-AgNCs, compares their antibacterial effectiveness at different pH levels, and evaluates cytotoxicity to various mammalian cell lines.
Article
Polymer Science
Ignacio A. Jessop, Yasmin P. Perez, Andrea Jachura, Hipolito Nunez, Cesar Saldias, Mauricio Isaacs, Alain Tundidor-Camba, Claudio A. Terraza, Ingrid Araya-Duran, Maria B. Camarada, Jose J. Carcamo-Vega
Summary: A hybrid composite of metallic copper nanoparticles (CuNPs) and a novel cationic pi-conjugated polyelectrolyte (CPE) was designed and synthesized, showing antibacterial activity against both Gram-positive and Gram-negative bacteria, primarily due to the effects of CuNPs.
Article
Chemistry, Physical
Bo Ma, Jai Prakash Chaudhary, Jianguo Zhu, Bianjing Sun, Chuntao Chen, Dongping Sun
Summary: Carbon materials are widely used in water treatment, but the breeding of bacteria on their surface can degrade water quality. In this study, antibacterial carbonized bacterial cellulose (CBC) composites with well-dispersed silver nanoparticles were synthesized using bacterial cellulose (BC) as a carbon source. The formed composites (Ag@CBC) showed excellent antibacterial activity with promising applications in water purification, exhibiting minimal inhibitory concentrations against S. aureus and E. coli.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2021)
Article
Chemistry, Analytical
Shemsu Ligani Fereja, Ping Li, Jinhan Guo, Zhongying Fang, Ziwei Zhang, Zhihua Zhuang, Xiaohui Zhang, Kaifan Liu, Wei Chen
Summary: Folic acid is a crucial water-soluble vitamin deficiency of which leads to various abnormalities in the human body. Researchers successfully synthesized luminescent Au-Ag bimetallic nanoclusters for folic acid detection, showing high sensitivity and low detection limit.
Article
Biophysics
Nhu Hoa Thi Tran, Thang Bach Phan, Than Thi Nguyen, Heongkyu Ju
Summary: The scheme presented involves optical coupling of AgNPs-conjugated dye molecules into fiber optical modes for fluorescence detection, leading to enhanced signal-to-noise ratio. By immobilizing dye molecules on the fiber core surface, the emission-selective coupling into fiber modes effectively reduces background noise from false excitation detection and autofluorescence. The results show a 4.2-fold enhancement in S/N ratio compared to conventional fluorescence detection, making the fiber-based scheme suitable for high S/N ratio biochemical assays in small-sized devices with remote sensing capability.
BIOSENSORS & BIOELECTRONICS
(2021)
Article
Nanoscience & Nanotechnology
Doyun Kim, Kun Woo Park, Inhee Choi, Jung Tae Park
Summary: Conventional antibiotic treatment is difficult due to multidrug resistance caused by abuse. We developed a cobalt-silver bimetallic nanocomposite with strong antibacterial activity and photothermal conversion effect. This nanocomposite released antibacterial metal ions continuously and exhibited enhanced inhibition of bacterial growth even with a small amount.
ACS APPLIED MATERIALS & INTERFACES
(2023)
Article
Chemistry, Multidisciplinary
Naseer Ullah Khan, Zahir Muhammad, Xukun Liu, Jing Lin, Qihong Zheng, Huajie Zhang, Samiullah Malik, Hua He, Liming Shen
Summary: A substrate based on gold nanorods was developed to amplify fluorescence signals and improve the detection sensitivity of biomarkers in exosomes. The method demonstrated excellent performance in terms of detection sensitivity and accuracy, and holds potential for the identification of other biomarkers.
Article
Chemistry, Physical
Muhammad Ovais, Arbab Ali, Sana Ullah, Ali Talha Khalil, Atia Atiq, Maria Atiq, Nurcan Dogan, Zabta Khan Shinwari, Manzar Abbas
Summary: Increased antibiotic resistance is a major healthcare challenge, and short peptide-modulated metal nanomaterials offer a promising solution with their biocompatibility and reduced toxic effects. These composite nanoparticles have shown potential in fighting bacterial infections and wound disinfection.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Materials Science, Multidisciplinary
Amit Panwar, K. L. Yadav
Summary: Studying the antibacterial properties of Ag-ZnO nanostructures revealed their ability to penetrate bacterial cell walls, with a minimum inhibitory concentration of 140ug/ml.
Article
Nanoscience & Nanotechnology
Dayeong Kwon, Jun Young Kim, Sang-Hun Lee, Eunji Lee, Jeongyong Kim, Amit Kumar Harit, Han Young Woo, Jinsoo Joo
Summary: The characteristics of field effect transistors fabricated using two-dimensional transition-metal dichalcogenides can be modulated by surface treatment with an ionic pi-conjugated polyelectrolyte, resulting in a charge-transfer effect and enhanced photoresponsivity. The n-channel current of both the MoSe2 and WS2 FETs increased, and the photoluminescence peaks were red-shifted after treatment. The external quantum efficiency and photodetectivity of both FETs were enhanced by the charge-transfer effect.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Spectroscopy
Panpan Huo, Zhijian Li, Congcong Gong, Ruihong Yao, Congbin Fan, Zhao Chen, Shouzhi Pu
Summary: A fluorescent nanosensor based on NH2-UiO-66 and AgNPs has been developed for sensitive and selective detection of glutathione (GSH) in human serum.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Chemistry, Analytical
Pengfei Song, Pengbo Zhang, Ke Qin, Fengxia Su, Kejian Gao, Xin Liu, Zhengping Li
Summary: This study utilizes CRISPR/Cas13a to recognize the unique junction sequence of circRNA and develops a CRISPR/Cas13a induced exponential amplification assay for sensitive and specific detection of circRNA. The designed primers and high amplification efficiency allow for the detection of low concentrations of circRNA in real biological samples.
Article
Chemistry, Analytical
Pengbo Zhang, Ke Qin, Anand Lopez, Zhengping Li, Juewen Liu
Summary: In this study, a cationic conjugated polymer (CCP)-based binding assay was developed for aptamer binding. The conformational change of aptamer after binding with a target was reflected by the fluorescence change of the CCP. Four aptamers for different targets were characterized, and the longer stem of the stem-loop structured aptamer facilitated target binding and enlarged the detection signal. This label-free and cost-effective method showed high specificity and sensitivity, making it a useful tool for aptamer binding evaluation and target detection.
ANALYTICAL CHEMISTRY
(2022)
Article
Biophysics
Yang Sun, Cheng Yang, Xiaolin Jiang, Pengbo Zhang, Shuo Chen, Fengxia Su, Hui Wang, Weiliang Liu, Xiaofei He, Lei Chen, Baoyuan Man, Zhengping Li
Summary: By combining CRISPR-Cas13a with a stabilized graphene field-effect transistor, a collaborative system was developed to detect SARS-CoV-2 with high-intensity vector signals, eliminating false detections and achieving high sensitivity.
BIOSENSORS & BIOELECTRONICS
(2023)
Article
Chemistry, Analytical
Ke Qin, Pengbo Zhang, Zhengping Li
Summary: The prevalence of antibiotic-resistant bacterial infections has raised social concern and a rapid, sensitive and specific detection method is urgently needed. This study demonstrates a novel strategy using CRISPR/Cas9 induced isothermal exponential amplification reaction (IEXPAR) to specifically distinguish and detect antibiotic-resistant bacteria. The method shows high specificity, accuracy and rapidness.
Article
Materials Science, Multidisciplinary
Bowen Li, Yuetong Kang, Xiaoyu Wang, Pengbo Zhang, Lidong Li
Summary: This study presents a photofunctional fibrous substrate by decorating photothermal gold nanoclusters to modulate cell growth. The gold nanoclusters were integrated with filamentous aggregates of gellan gum and bioactive whey protein through ionic crosslinks. The gold nanoclusters enhanced the arrangement of fibrous structures, increased substrate rigidity, promoted cell adhesion, and allowed on-demand release of whey protein to induce cell proliferation.
JOURNAL OF MATERIALS CHEMISTRY C
(2023)
Article
Chemistry, Analytical
Pengbo Zhang, Mohamad Zandieh, Yuzhe Ding, Lyuyuan Wu, Xiaoyu Wang, Juewen Liu, Zhengping Li
Summary: A cationic conjugated polymer (CCP)-based assay was studied for the accurate measurement of concentration of single-stranded DNA (ssDNA). The method utilized the fluorescence change of CCPs upon binding ssDNA and achieved a high binding affinity with ssDNA. The developed CCP-based biosensor showed comparable detection limit and better suitability for ssDNA measurement compared to fluorescence-dye-based methods.
Article
Chemistry, Multidisciplinary
Huanxiang Yuan, Zelin Li, Qi Zhao, Shaochuan Jia, Ting Wang, Li Xu, Haitao Yuan, Shengliang Li
Summary: Infectious diseases caused by pathogenic microorganisms can have serious consequences and threaten life. Drug-resistant bacteria have made traditional antibiotics less effective. This study develops conjugated oligomers with tunable backbones for regulating their photo-thermal conversion, which show high photothermal conversion efficiency. The resulting nanoparticles have strong antimicrobial activity against drug-resistant bacteria under near-infrared irradiation, promoting wound healing in diabetic mice. This work provides ideas for designing efficient antimicrobial agents against drug-resistant microbial infections activated by near-infrared.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Chemistry, Physical
Jianfeng Zhang, Chuang Yao, Xinhui Liu, Ziyi Ding, Yuan Liu, Baoxing Liu, Sunbin Deng, Hoi-Sing Kwok, Guijun Li
Summary: There is a growing demand for convenient and cost-efficient ethanol sensing techniques in daily life and industry. However, the complexity, high cost, and large volume of conventional techniques hinder their widespread use. In this study, a test paper-like ethanol sensing platform is introduced, which utilizes the instability of 2D Ruddlesden-Popper perovskite in ethanol. The platform demonstrates rapid and convenient ethanol sensing performance, making it a potential supplement to existing ethanol sensing techniques.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Analytical
Fengxia Su, Xiaofei He, Pengbo Zhang, Hui Wang, Zhengping Li
Summary: The COVID-19 epidemic caused by the SARS-CoV-2 virus has had a significant negative impact on society and global health. A sensitive, quick, and reasonably priced SARS-CoV-2 detection technology is urgently needed. Reverse transcription-loop-mediated isothermal amplification (RT-LAMP) is a promising method that amplifies a small amount of RNA to a detectable level at isothermal condition without the need for expensive equipment. In this study, a water-soluble polythiophene-based colorimetric method combined with RT-LAMP was established for fast and sensitive detection of SARS-CoV-2 RNA.
Review
Chemistry, Multidisciplinary
Ka-Wai Lee, Yingpeng Wan, Zhongming Huang, Qi Zhao, Shengliang Li, Chun-Sing Lee
Summary: This review summarizes the recent development of organic optoelectronic materials (OOMs) for biomedical applications, specifically in fluorescence imaging, photoacoustic imaging, photothermal therapy, and photodynamic therapy. The relationships between the molecular structures, nanoaggregation structures, photophysical mechanisms, and properties of OOMs for different biomedical applications are discussed. The review also highlights the challenges and future perspectives of OOMs for efficient biomedical applications.
ADVANCED MATERIALS
(2023)
Article
Materials Science, Biomaterials
Qi Long, Yuliang Yang, Fangling Liao, Haoting Chen, Dongyue He, Shengliang Li, Pengcheng Li, Weisheng Guo, Yafang Xiao
Summary: Photothermal immunotherapy has potential for efficient cancer treatment, but the immunosuppressive tumor microenvironment and lack of reliable imaging modalities are challenges. The theranostic thermosensitive liposome (PLDD) we designed can boost the adaptive anti-tumor immunity and provide real-time multimodal imaging.
JOURNAL OF MATERIALS CHEMISTRY B
(2023)
Article
Chemistry, Multidisciplinary
Sheng Zhang, Junheng Gao, Fu Tang, Jie Wang, Chuang Yao, Lidong Li
Summary: A seedless wet method for the synthesis of copper twinned nanostructures has been proposed in this study, which successfully synthesized large copper decahedrons and singly twinned copper right bipyramids. Different kinds of copper twinned nanostructures could be obtained by adjusting the amount of chloride ions and oleylamine.
Article
Nanoscience & Nanotechnology
Qian Zhang, Xiaoyu Wang, Yuetong Kang, Chuang Yao, XinRui Li, Lidong Li
Summary: Hydrogels using natural and synthetic polymers have attracted attention for various bioapplications, but inhibiting bacterial infection remains a challenge. In this study, a supramolecular hydrogel with good antibacterial properties was reported, which can be excited by light to produce antibacterial effects and resist protein and bacterial adsorption through its superhydrophilic surface.
ACS APPLIED BIO MATERIALS
(2022)
Article
Chemistry, Multidisciplinary
Jie Wang, Fu Tang, Junheng Gao, Chuang Yao, Sheng Zhang, Lidong Li
Summary: In this study, plate-like Cu2O mesocrystals were successfully fabricated using a simple wet chemical strategy. Chloride ions were employed as structure-directing agents to inhibit the formation of CuO and Cu and promote the formation of Cu2O nanocrystals. The plate-like Cu2O mesocrystals showed excellent performance in the visible-light-driven photocatalytic reduction of N-2 into NH3.
Article
Materials Science, Multidisciplinary
Yezi Yang, Chuang Yao, Lei Li, Maolin Bo, Meng He, Jinshan Wang
Summary: This study investigates the properties and performance of three isomeric NFAs based on a 2D fused-ring core and four electron-withdrawing end groups. The results show that isomerism of the conjugated backbone is an effective method to alter the optoelectronic properties of NFA materials. Among them, d-2D-ICH exhibits superior optical and electrical properties, making it a promising candidate for high-performance organic solar cells.
JOURNAL OF MATERIALS CHEMISTRY C
(2022)