KDM2 Family Members are Regulated by HIF-1 in Hypoxia

Erratum: ATM-mediated KDM2A phosphorylation is required for the DNA damage repair

(2016) L-L Cao et al.   ONCOGENE

Lysine demethylase 2A promotes stemness and angiogenesis of breast cancer by upregulating Jagged1

(2016) Jing-Yi Chen et al.   Oncotarget

Kdm2a/b Lysine Demethylases Regulate Canonical Wnt Signaling by Modulating the Stability of Nuclear β-Catenin

(2015) Lei Lu et al.   DEVELOPMENTAL CELL

Mild Glucose Starvation Induces KDM2A-Mediated H3K36me2 Demethylation through AMPK To Reduce rRNA Transcription and Cell Proliferation

(2015) Yuji Tanaka et al.   MOLECULAR AND CELLULAR BIOLOGY

Integrated genomic and functional analyses of histone demethylases identify oncogenic KDM2A isoform in breast cancer

(2015) Hui Liu et al.   MOLECULAR CARCINOGENESIS

Oxygen Sensing and Homeostasis

(2015) Nanduri R. Prabhakar et al.   PHYSIOLOGY

Chromatin and oxygen sensing in the context of JmjC histone demethylases

(2014) Alena Shmakova et al.   BIOCHEMICAL JOURNAL

Hypoxia activates IKK–NF-κB and the immune response inDrosophila melanogaster

(2014) Daniel Bandarra et al.   BIOSCIENCE REPORTS

HIF-1α restricts NF-κB-dependent gene expression to control innate immunity signals

(2014) Daniel Bandarra et al.   Disease Models & Mechanisms

The multifaceted von Hippel-Lindau tumour suppressor protein

(2014) Claire M. Robinson et al.   FEBS LETTERS

Histone demethylase KDM2A promotes tumor cell growth and migration in gastric cancer

(2014) Yufeng Huang et al.   TUMOR BIOLOGY

Extensive regulation of the non-coding transcriptome by hypoxia: role of HIF in releasing paused RNApol2

(2013) Hani Choudhry et al.   EMBO REPORTS

KDM2B promotes pancreatic cancer via Polycomb-dependent and -independent transcriptional programs

(2013) Alexandros Tzatsos et al.   JOURNAL OF CLINICAL INVESTIGATION

KDM2A promotes lung tumorigenesis by epigenetically enhancing ERK1/2 signaling

(2013) Klaus W. Wagner et al.   JOURNAL OF CLINICAL INVESTIGATION

Kdm2b maintains murine embryonic stem cell status by recruiting PRC1 complex to CpG islands of developmental genes

(2013) Jin He et al.   NATURE CELL BIOLOGY

Investigations on the oxygen dependence of a 2-oxoglutarate histone demethylase

(2012) Elena M. Sánchez-Fernández et al.   BIOCHEMICAL JOURNAL

OMERO: flexible, model-driven data management for experimental biology

(2012) Chris Allan et al.   NATURE METHODS

KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia

(2011) J. He et al.   BLOOD

F-box protein 10, an NF-κB-dependent anti-apoptotic protein, regulates TRAIL-induced apoptosis through modulating c-Fos/c-FLIP pathway

(2011) R Ge et al.   CELL DEATH AND DIFFERENTIATION

Chromatin as an oxygen sensor and active player in the hypoxia response

(2011) Andrew Melvin et al.   CELLULAR SIGNALLING

The von Hippel–Lindau tumor suppressor protein regulates gene expression and tumor growth through histone demethylase JARID1C

(2011) X Niu et al.   ONCOGENE

Genetic and Functional Studies Implicate HIF1  as a 14q Kidney Cancer Suppressor Gene

(2011) C. Shen et al.   Cancer Discovery

The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism

(2010) Na Zhang et al.   Cell Metabolism

JmjC enzyme KDM2A is a regulator of rRNA transcription in response to starvation

(2010) Yuji Tanaka et al.   EMBO JOURNAL

Mechanism of Hypoxia-Induced NF- B

(2010) C. Culver et al.   MOLECULAR AND CELLULAR BIOLOGY

Signalling Cross Talk of the HIF System: Involvement of the FIH Protein

(2009) M. Coleman et al.   CURRENT PHARMACEUTICAL DESIGN

Regulation of the Histone Demethylase JMJD1A by Hypoxia-Inducible Factor 1  Enhances Hypoxic Gene Expression and Tumor Growth

(2009) A. J. Krieg et al.   MOLECULAR AND CELLULAR BIOLOGY

Regulation of NF- B by NSD1/FBXL11-dependent reversible lysine methylation of p65

(2009) T. Lu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypoxia upregulates the histone demethylase JMJD1A via HIF-1

(2008) Sven Wellmann et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1α

(2008) Patrick J. Pollard et al.   BIOCHEMICAL JOURNAL

The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF

(2008) Sophie Beyer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY