Application of Induced Pluripotent Stem Cell Technology to the Study of Hematological Diseases

Targeted Application of Human Genetic Variation Can Improve Red Blood Cell Production from Stem Cells

(2016) Felix C. Giani et al.   Cell Stem Cell

How iPS cells changed the world

(2016) Megan Scudellari   NATURE

Progress towards generation of human haematopoietic stem cells

(2016) Lara Wahlster et al.   NATURE CELL BIOLOGY

CRISPR-Cas immunity in prokaryotes

(2015) Luciano A. Marraffini   NATURE

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

(2015) Andriana G Kotini et al.   NATURE BIOTECHNOLOGY

Improved Hematopoietic Differentiation Efficiency of Gene-Corrected Beta-Thalassemia Induced Pluripotent Stem Cells by CRISPR/Cas9 System

(2015) Bing Song et al.   STEM CELLS AND DEVELOPMENT

Dissecting the role of aberrant DNA methylation in human leukaemia

(2015) Giovanni Amabile et al.   Nature Communications

Pluripotent Cell Models of Fanconi Anemia Identify the Early Pathological Defect in Human Hemoangiogenic Progenitors

(2015) Naoya M. Suzuki et al.   Stem Cells Translational Medicine

Efficient Generation of Megakaryocytes From Human Induced Pluripotent Stem Cells Using Food and Drug Administration-Approved Pharmacological Reagents

(2015) Yanfeng Liu et al.   Stem Cells Translational Medicine

Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types

(2014) Nils J Fredriksson et al.   NATURE GENETICS

HLA Match Likelihoods for Hematopoietic Stem-Cell Grafts in the U.S. Registry

(2014) Loren Gragert et al.   NEW ENGLAND JOURNAL OF MEDICINE

Cardiovascular toxicity and titin cross-reactivity of affinity-enhanced T cells in myeloma and melanoma

(2013) G. P. Linette et al.   BLOOD

Umbilical cord blood transplantation: the first 25 years and beyond

(2013) K. K. Ballen et al.   BLOOD

Regeneration of Human Tumor Antigen-Specific T Cells from iPSCs Derived from Mature CD8 + T Cells

(2013) Raul Vizcardo et al.   Cell Stem Cell

Generation of Rejuvenated Antigen-Specific T Cells by Reprogramming to Pluripotency and Redifferentiation

(2013) Toshinobu Nishimura et al.   Cell Stem Cell

Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy

(2013) Maria Themeli et al.   NATURE BIOTECHNOLOGY

Robust and Highly-Efficient Differentiation of Functional Monocytic Cells from Human Pluripotent Stem Cells under Serum- and Feeder Cell-Free Conditions

(2013) Masakatsu D. Yanagimachi et al.   PLoS One

Genomic Characterization of the Inherited Bone Marrow Failure Syndromes

(2013) Payal P. Khincha et al.   SEMINARS IN HEMATOLOGY

Clinical-Scale Derivation of Natural Killer Cells From Human Pluripotent Stem Cells for Cancer Therapy

(2013) David A. Knorr et al.   Stem Cells Translational Medicine

Generation of induced pluripotent stem cells from primary chronic myelogenous leukemia patient samples

(2012) K. Kumano et al.   BLOOD

In vivo generation of transplantable human hematopoietic cells from induced pluripotent stem cells

(2012) G. Amabile et al.   BLOOD

The three human monocyte subsets: implications for health and disease

(2012) Kok Loon Wong et al.   IMMUNOLOGIC RESEARCH

A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

(2012) M. Jinek et al.   SCIENCE

Human induced pluripotent stem cells are capable of B-cell lymphopoiesis

(2011) L. Carpenter et al.   BLOOD

Better prognosis for patients with del(7q) than for patients with monosomy 7 in myelodysplastic syndrome

(2011) Iris Cordoba et al.   CANCER

Production of Embryonic and Fetal-Like Red Blood Cells from Human Induced Pluripotent Stem Cells

(2011) Chan-Jung Chang et al.   PLoS One

Generation of iPSCs from cultured human malignant cells

(2010) J. E. Carette et al.   BLOOD

Red blood cell generation from human induced pluripotent stem cells: perspectives for transfusion medicine

(2010) H. Lapillonne et al.   HAEMATOLOGICA

Transient activation ofc-MYCexpression is critical for efficient platelet generation from human induced pluripotent stem cells

(2010) Naoya Takayama et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Human Pluripotent Stem Cells Produce Natural Killer Cells That Mediate Anti-HIV-1 Activity by Utilizing Diverse Cellular Mechanisms

(2010) Z. Ni et al.   JOURNAL OF VIROLOGY

Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution

(2010) Colleen Delaney et al.   NATURE MEDICINE

Human-induced pluripotent stem cells from blood cells of healthy donors and patients with acquired blood disorders

(2009) Z. Ye et al.   BLOOD

Human embryonic stem cells differentiate into a homogeneous population of natural killer cells with potent in vivo antitumor activity

(2009) P. S. Woll et al.   BLOOD

Autologous blood cell therapies from pluripotent stem cells

(2009) Claudia Lengerke et al.   BLOOD REVIEWS

Generation of mature human myelomonocytic cells through expansion and differentiation of pluripotent stem cell–derived lin–CD34+CD43+CD45+ progenitors

(2009) Kyung-Dal Choi et al.   JOURNAL OF CLINICAL INVESTIGATION

Generation of functional platelets from human embryonic stem cells in vitro via ES-sacs, VEGF-promoted structures that concentrate hematopoietic progenitors

(2008) N. Takayama et al.   BLOOD

Disease-Specific Induced Pluripotent Stem Cells

(2008) In-Hyun Park et al.   CELL

A Combined Chemical and Genetic Approach for the Generation of Induced Pluripotent Stem Cells

(2008) Yan Shi et al.   Cell Stem Cell

Generation of Induced Pluripotent Stem Cells from Adult Rhesus Monkey Fibroblasts

(2008) Haisong Liu et al.   Cell Stem Cell

Efficient Hematopoietic Differentiation of Human Embryonic Stem Cells on Stromal Cells Derived from Hematopoietic Niches

(2008) Maria H. Ledran et al.   Cell Stem Cell

Induction of pluripotent stem cells by defined factors is greatly improved by small-molecule compounds

(2008) Danwei Huangfu et al.   NATURE BIOTECHNOLOGY

Generation of human induced pluripotent stem cells from dermal fibroblasts

(2008) W. E. Lowry et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Generation of Pluripotent Stem Cells from Adult Mouse Liver and Stomach Cells

(2008) T. Aoi et al.   SCIENCE

Generation of Mouse Induced Pluripotent Stem Cells Without Viral Vectors

(2008) K. Okita et al.   SCIENCE