APOLs with low pH dependence can kill all African trypanosomes

Apolipoproteins L control cell death triggered by TLR3/TRIF signaling in dendritic cells

(2016) Sophie Uzureau et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A Primate APOL1 Variant That Kills Trypanosoma brucei gambiense

(2016) Anneli Cooper et al.   PLoS Neglected Tropical Diseases

Trypanosome Lytic Factor-1 Initiates Oxidation-stimulated Osmotic Lysis ofTrypanosoma brucei brucei

(2015) Amy Styer Greene et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human trypanolytic factor APOL1 forms pH-gated cation-selective channels in planar lipid bilayers: Relevance to trypanosome lysis

(2015) Russell Thomson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coupling of lysosomal and mitochondrial membrane permeabilization in trypanolysis by APOL1

(2015) Gilles Vanwalleghem et al.   Nature Communications

Identification ofTrypanosoma bruceicomponents involved in trypanolysis by normal human serum

(2014) Laurence Lecordier et al.   MOLECULAR MICROBIOLOGY

The molecular arms race between African trypanosomes and humans

(2014) Etienne Pays et al.   NATURE REVIEWS MICROBIOLOGY

Melarsoprol Sensitivity Profile of Trypanosoma brucei gambiense Isolates from Cured and Relapsed Sleeping Sickness Patients from the Democratic Republic of the Congo

(2014) Patient Pyana Pati et al.   PLoS Neglected Tropical Diseases

Cathepsin-L Can Resist Lysis by Human Serum in Trypanosoma brucei brucei

(2014) Sam Alsford et al.   PLoS Pathogens

Plasma Apolipoprotein L1 Levels Do Not Correlate with CKD

(2013) L. A. Bruggeman et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Molecular one-upmanship

(2013) Jayne Raper et al.   NATURE

Mechanism of Trypanosoma brucei gambiense resistance to human serum

(2013) Pierrick Uzureau et al.   NATURE

The TgsGP Gene Is Essential for Resistance to Human Serum in Trypanosoma brucei gambiense

(2013) Paul Capewell et al.   PLoS Pathogens

Human apolipoprotein L1 (ApoL1) in cancer and chronic kidney disease

(2012) Chien-An A. Hu et al.   FEBS LETTERS

Roles of Carboxyl Groups in the Transmembrane Insertion of Peptides

(2011) Francisco N. Barrera et al.   JOURNAL OF MOLECULAR BIOLOGY

Putting sleeping sickness to bed

(2011) Cassandra Willyard   NATURE MEDICINE

Association of Trypanolytic ApoL1 Variants with Kidney Disease in African Americans

(2010) G. Genovese et al.   SCIENCE

Hydrodynamic gene delivery of baboon trypanosome lytic factor eliminates both animal and human-infective African trypanosomes

(2009) R. Thomson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

C-Terminal Mutants of Apolipoprotein L-I Efficiently Kill Both Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense

(2009) Laurence Lecordier et al.   PLoS Pathogens