期刊
ANNUAL REVIEW OF VISION SCIENCE, VOL 3
卷 3, 期 -, 页码 141-166出版社
ANNUAL REVIEWS
DOI: 10.1146/annurev-vision-111815-114525
关键词
visual cortex; phosphene; visual cortical prosthetic; electrical stimulation; direct current stimulation
资金
- NEI NIH HHS [R01 EY023336] Funding Source: Medline
- CSRD VA [I01 CX001122] Funding Source: Medline
Electrical stimulation of the cerebral cortex is a powerful tool for exploring cortical function. Stimulation of early visual cortical areas is easily detected by subjects and produces simple visual percepts known as phosphenes. A device implanted in visual cortex that generates patterns of phosphenes could be used as a substitute for natural vision in blind patients. We review the possibilities and limitations of such a device, termed a visual cortical prosthetic. Currently, we can predict the location and size of phosphenes produced by stimulation of single electrodes. A functional prosthetic, however, must produce spatial temporal patterns of activity that will result in the perception of complex visual objects. Although stimulation of later visual cortical areas alone usually does not lead to a visual percept, it can alter visual perception and the performance of visual behaviors, and training subjects to use signals injected into these areas may be possible.
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