Article
Clinical Neurology
Mique Saes, Carel G. M. Meskers, Andreas Daffertshofer, Erwin E. H. van Wegen, Gert Kwakkel
Summary: Resting-state EEG parameters can predict upper extremity motor impairment after stroke, with BSItheta showing the strongest predictive value. BSItheta provides unique prognostic information regarding upper extremity motor recovery, in addition to baseline FM-UE scores.
CLINICAL NEUROPHYSIOLOGY
(2021)
Article
Clinical Neurology
Ze-Jian Chen, Chang He, Jiang Xu, Chan-Juan Zheng, Jing Wu, Nan Xia, Qiang Hua, Wen-Guang Xia, Cai-Hua Xiong, Xiao-Lin Huang
Summary: This study aimed to compare conventional therapist-mediated training with exoskeleton-assisted anthropomorphic movement training for patients after stroke. The results showed that patients who received exoskeleton-assisted training had higher scores in the Fugl-Meyer Assessment for Upper Extremity at 4 weeks. Therefore, exoskeleton-assisted anthropomorphic movement training appears to be effective for stroke rehabilitation.
Review
Medicine, General & Internal
Lorenna R. D. M. Borges, Aline B. G. S. Fernandes, Luciana Protasio Melo, Ricardo O. Guerra, Tania F. Campos
Summary: This study evaluated the effects of action observation on upper limb motor function in stroke patients, finding that action observation has a certain improvement effect on arm and hand function, but not significant impact on activities of daily living and quality of life.
COCHRANE DATABASE OF SYSTEMATIC REVIEWS
(2022)
Article
Robotics
Chingyi Nam, Wei Rong, Waiming Li, Chingyee Cheung, Wingkit Ngai, Tszching Cheung, Mankit Pang, Li Li, Junyan Hu, Honwah Wai, Xiaoling Hu
Summary: This article presents a novel electromyography (EMG)-driven exoneuromusculoskeleton that integrates the neuromuscular electrical stimulation (NMES), soft pneumatic muscle, and exoskeleton techniques, for self-help upper limb training after stroke. The developed system provides significant improvement in limb performance and muscular coordination, supporting self-help upper limb rehabilitation after stroke.
Article
Geriatrics & Gerontology
Jing Ni, Wei Jiang, Xueyang Gong, Yingjie Fan, Hao Qiu, Jiaming Dou, Juan Zhang, Hongxing Wang, Chunguang Li, Min Su
Summary: This study evaluated the effects of different rTMS stimulation programs on upper limb function and brain functional network characteristics of stroke patients. The results showed that rTMS treatment is beneficial for the recovery of upper limb motor function and can improve brain network connectivity and reduce island areas.
FRONTIERS IN AGING NEUROSCIENCE
(2023)
Article
Clinical Neurology
Jae Joon Lee, Joon-Ho Shin
Summary: This study aimed to identify meaningful predictors and a prediction model for clinically significant motor improvement in upper limb impairment after robot-assisted therapy for stroke patients in different phases. The results showed that hand movement scale and time since onset were significant predictors for substantial motor improvement in patients with subacute stroke, with borderline statistical significance in chronic stroke patients.
FRONTIERS IN NEUROLOGY
(2021)
Article
Clinical Neurology
Kathryn S. Hayward, Jennifer K. Ferris, Keith R. Lohse, Michael R. Borich, Alexandra Borstad, Jessica M. Cassidy, Steven C. Cramer, Sean P. Dukelow, Sonja E. Findlater, Rachel L. Hawe, Sook-Lei Liew, Jason L. Neva, Jill C. Stewart, Lara A. Boyd
Summary: This study aims to evaluate the relationship between white matter microstructure in the corpus callosum (CC) and severe upper limb (UL) impairment poststroke. The results demonstrate that CC microstructure relates to motor outcome, particularly in patients with severe impairment. These findings suggest that CC microstructure may serve as a promising biomarker for severe UL outcome after stroke.
Article
Clinical Neurology
Yeun Jie Yoo, So Yeon Jun, Eun Jin Park, Youngkook Kim
Summary: This study aimed to determine the measurement accuracy of the structural integrity of the corticospinal tract (CST) using diffusion tensor imaging. The results showed that the structural integrity measurements at the pontomedullary junction or entire CST demonstrated the highest accuracy in the subacute phase of stroke for assessing upper limb function.
Article
Medicine, General & Internal
S. Wolf, S. E. Holm, T. Ingwersen, C. Bartling, G. Bender, G. Birke, A. Meyer, A. Nolte, K. Ottes, O. Pade, M. Peller, J. Steinmetz, C. Gerloff, G. Thomalla
Summary: Socioeconomic status has a significant impact on the long-term recovery of stroke patients, with higher socioeconomic status associated with better recovery, higher utilization of outpatient therapy.
ANNALS OF MEDICINE
(2022)
Review
Engineering, Biomedical
Ioannis Doumas, Gauthier Everard, Stephanie Dehem, Thierry Lejeune
Summary: This systematic review assessed the efficacy of serious games for upper limb recovery after stroke, showing that serious games lead to better improvements compared to conventional treatment. Adherence to neurorehabilitation principles enhances the efficacy of serious games, with long-term effects observed.
JOURNAL OF NEUROENGINEERING AND REHABILITATION
(2021)
Article
Chemistry, Analytical
Bea Essers, Camilla Biering Lundquist, Geert Verheyden, Iris Charlotte Brunner
Summary: The study examined different aspects of upper-limb activity in chronic stroke and found that motor impairment and biological factors accounted for only a portion of the variance in activity. Rehabilitation including behavioral strategies may be important in increasing the different aspects of upper-limb activity.
Article
Neurosciences
Hewei Wang, Xin Xiong, Kexu Zhang, Xu Wang, Changhui Sun, Bing Zhu, Yiming Xu, Mingxia Fan, Shanbao Tong, Xiaoli Guo, Limin Sun
Summary: This study aimed to investigate the neural mechanisms of motor imagery training (MIT) in stroke rehabilitation. The results showed that MIT could decrease compensatory activation at both hemispheres and reshape the functional connectivity within the ipsilesional hemisphere, promoting motor recovery in stroke patients.
CNS NEUROSCIENCE & THERAPEUTICS
(2023)
Article
Clinical Neurology
Jinjin Mei, Yang Xue, Jingwen Li, Lihong Zhang, Jianyun Zhang, Yiying Wang, Kaiqi Su, Jing Gao, Jian Guo, Ruiqing Li
Summary: This article presents a clinical study on the efficacy of functional acupuncture for upper limb spasticity after ischemic stroke. The findings will provide new insights into the treatment of upper limb spasticity after stroke and offer effective experimental support and theoretical basis for clinical practice.
FRONTIERS IN NEUROLOGY
(2022)
Article
Clinical Neurology
Qiuwen Gong, Rubing Yan, Han Chen, Xia Duan, Xiaoyu Wu, Xin Zhang, Yi Zhou, Zhou Feng, Ya Chen, Jianbo Liu, Peng Xu, Jing Qiu, Hongliang Liu, Jingming Hou
Summary: This study found that cerebellar transcranial direct current stimulation (tDCS) therapy can effectively and safely promote the recovery of upper limb motor function in stroke patients through a randomized trial.
FRONTIERS IN NEUROLOGY
(2023)
Article
Health Care Sciences & Services
Silvia Salvalaggio, Luisa Cacciante, Lorenza Maistrello, Andrea Turolla
Summary: After stroke, a high dose of rehabilitation can enhance the recovery of upper limb motor function, and it is believed to be supported by attentive functions. However, the mutual influence between them during rehabilitation is still unknown. This retrospective observational cohort study aimed to investigate the association between rehabilitation dose and motor and cognitive functions during upper limb motor recovery. The results showed that the total amount of rehabilitation delivered was the strongest factor influencing the recovery of upper limb motor function after stroke, while cognitive-linguistic characteristics did not have an influence on upper limb motor gains.
Article
Rehabilitation
Stephanie Thompson, William Levack, Jeroen Douwes, Jackie Girvan, Ginny Abernethy, P. Alan Barber, John Fink, John Gommans, Alan Davis, Matire Harwood, Dominique A. Cadilhac, Harry McNaughton, Valery Feigin, Andrew Wilson, Hayley Denison, Marine Corbin, Joosup Kim, Annemarei Ranta
Summary: It is important to understand the perceptions of stroke care services from both consumers (people with stroke/family members/caregivers) and health workers. A survey was conducted among consumers and health workers from across New Zealand to gather their views on stroke care, access barriers, and service centralization. The results indicated differences in perceptions between consumers and health workers, highlighting the need for involving both parties in service co-design. Improving communication, post-hospital follow-up, and geographic equity emerged as key areas for improvement.
DISABILITY AND REHABILITATION
(2023)
Article
Public, Environmental & Occupational Health
Shyam Gangadharan, Shinya Tomari, Christopher R. Levi, Natasha Weaver, Elizabeth Holliday, Beata Bajorek, Daniel Lasserson, Jose M. Valderas, Helen M. Dewey, Peter Alan Barber, Neil J. Spratt, Dominique A. Cadilhac, Valery L. Feigin, Peter M. Rothwell, Hossein Zareie, Carlos Garcia-Esperon, Andrew Davey, Nashwa Najib, Milton Sales, Parker Magin
Summary: This study compared the processes of care and clinical outcomes of community-based management of TIAMS between rural and metropolitan Australia. The study found that while the prognosis of TIAMS in rural settings is very good, the processes of care in such areas are inferior to metropolitan areas.
AUSTRALIAN JOURNAL OF RURAL HEALTH
(2023)
Article
Clinical Neurology
Alexander Berry-Noronha, Daniel Myall, Jae Beom Hong, Wayne Collecutt, Martin Krauss, John Fink, Susan Weggery, Animesh Chatterjee, Sam Bartholomew, Mark Smith, Campbell Le Heron, Wendy Busby, Stefan Brew, Peter Alan Barber, Teddy Y. Wu, Duncan Wilson
Summary: This study aimed to describe the characteristics and outcomes of patients with large vessel occlusion ischaemic stroke who were referred to a distant tertiary centre for delayed mechanical thrombectomy (MT). The results showed that delayed MT several hours after baseline NCCT could lead to good clinical outcomes in highly selected patients. However, older patients with diabetes, high NIHSS score, and low ASPECTS score may not benefit from transfer to a hub centre for MT.
EUROPEAN JOURNAL OF NEUROLOGY
(2023)
Article
Clinical Neurology
Carlos Garcia-Esperon, Teddy Y. Wu, Vinicius Carraro do Nascimento, Bernard Yan, Craig Kurunawai, Tim Kleinig, Gregory Selkirk, David Blacker, P. Alan Barber, Annemarei Ran, Alvaro Cervera, Andrew Wong, Peter Mitchell, Claire Muller, Hal Rice, Laetitia De Villiers, Jim Jannes, Jae Beom Hong, Peter Bailey, Helen Brown, Bruce C. Campbell, Duncan Wilson, John Fink, Timothy Ang, Christopher Bladin, Tim Phillip, Md Golam Hasnain, Kenneth Butcher, Ferdinand Miteff, Christopher R. Levi, Neil J. Spratt, Mark W. Parsons
Summary: This study retrospectively analyzed patients transferred for endovascular thrombectomy (EVT) and found that patients transferred over 300 miles can benefit from EVT, and the use of computed tomography perfusion (CTP) at the referring hospital can reduce poorer outcomes at 3 months.
Article
Clinical Neurology
Harriette Dunphy, Carlos Garcia-Esperon, Jae Beom Hong, Csilla Manoczki, Duncan Wilson, Beng Lim Alvin Chew, James Beharry, Andrew Bivard, Md Golam Hasnain, Martin Krauss, Wayne Collecutt, Ferdi Miteff, Neil Spratt, Mark W. Parsons, Peter Alan Barber, Annemarei Ranta, John N. Fink, Teddy Y. Wu
Summary: This study retrospectively analyzed the outcomes of endovascular thrombectomy (EVT) in patients aged over 80 years and found that selected very elderly patients, with similar baseline characteristics, have a similar likelihood of returning to baseline function following the procedure compared to younger patients, despite a higher all-cause 90-day mortality rate.
EUROPEAN STROKE JOURNAL
(2023)
Article
Clinical Neurology
Hayley J. Denison, Marine Corbin, Jeroen Douwes, Stephanie G. Thompson, Matire Harwood, Alan Davis, John N. Fink, P. Alan Barber, John H. Gommans, Dominique A. Cadilhac, William Levack, Harry McNaughton, Joosup Kim, Valery L. Feigin, Virginia Abernethy, Jackie Girvan, Andrew Wilson, Anna Ranta
Summary: This study assessed ethnic differences in stroke outcome and service access in New Zealand (NZ) and explored underlying causes in addition to traditional risk factors. The results showed that Maori people had a higher risk of unfavorable outcomes at different time points and higher risks of death, change in residence, and unemployment. The study suggests that these disparities may be associated with stroke service delivery.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Clinical Neurology
Douglas Campbell, Elise Butler, Ruby Blythe Campbell, Jess Ho, P. Alan Barber
Summary: For endovascular thrombectomy (EVT) in large vessel occlusion ischemic stroke, general anesthesia (GA) has been shown to improve recanalization rates and functional recovery compared to non-GA techniques. This meta-analysis of seven randomized controlled trials (RCTs) further supports the findings, revealing that GA improves recanalization by 9.0% and functional recovery by 8.4% compared to non-GA techniques. There were no significant differences in hemorrhagic complications or mortality.
Editorial Material
Clinical Neurology
Peter Alan Barber
Summary: In the study, Scott et al. compared the diagnostic accuracy of telestroke assessments inside the ambulance with the Prehospital Acute Stroke Triage and Assessment (PASTA) score, based on the Los Angeles Motor Scale. The authors found that telestroke assessments were more likely to predict treatment with intravenous thrombolysis and endovascular thrombectomy than PASTA.
Article
Clinical Neurology
Joosup Kim, Dominique A. Cadilhac, Stephanie Thompson, John Gommans, Alan Davis, P. Alan Barber, John Fink, Matire Harwood, William Levack, Harry McNaughton, Virginia Abernethy, Jacqueline Girvan, Valery Feigin, Hayley Denison, Marine Corbin, Andrew Wilson, Jeroen Douwes, Anna Ranta
Summary: This study compared the costs and quality-adjusted life years of stroke patients admitted to urban and nonurban hospitals in New Zealand. The results showed that urban hospitals had higher treatment costs and quality-adjusted life years compared to nonurban hospitals, even after adjustment for other factors. These findings can help improve the level of treatment in nonurban hospitals and optimize outcomes for patients.
Article
Clinical Neurology
Marie-Claire Smith, Benjamin J. Scrivener, Cathy M. Stinear
Summary: This observational study investigated whether lower limb motor-evoked potentials 1 week post-stroke can predict recovery of independent walking at 3 and 6 months post-stroke. The results showed that the presence of lower limb motor-evoked potentials can predict independent walking at 3 and 6 months post-stroke, but clinical factors are more important.
JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
(2023)
Article
Clinical Neurology
Benjamin Chong, Alan Wang, Cathy M. M. Stinear
Summary: Baseline scores and extent of impairment after stroke are important predictors of post-stroke outcomes. However, the validity of proportional recovery as a model has been questioned due to confounding factors and critiques. This article reviews the current understanding of proportional recovery, discusses potential confounds, and evaluates its usefulness in post-stroke recovery research.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Review
Clinical Neurology
Ji-Hun Yoo, Benjamin Chong, Peter Alan Barber, Cathy Stinear, Alan Wang
Summary: This review examines the methodologies currently used in motor outcome prediction studies using atlas-based voxel neuroimaging features. The study found that there are various limitations in the current methods, such as a lack of detailed reporting on image acquisition and a lack of consensus on the use of a single sensorimotor atlas for prediction. Therefore, there is a need for further validation and improvement in neuroimaging feature development for motor outcome prediction.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
Review
Clinical Neurology
Afifa Safdar, Marie-Claire Smith, Winston D. Byblow, Cathy M. Stinear
Summary: This review assessed the application of rTMS protocols for improving upper limb motor performance after stroke. The majority of studies still follow the interhemispheric competition model and do not consider the bimodal balance recovery model. Future studies should select patients and apply rTMS protocols based on ipsilesional corticomotor function.
NEUROREHABILITATION AND NEURAL REPAIR
(2023)
