Article
Microbiology
B. Sophatha, R. Teanpaisan
Summary: This study investigates the effects of various factors on adhesion and aggregation abilities of Lactobacillus strains derived from the human oral cavity. It suggests that bacterial adhesion is strain-specific and may depend on its origin, while positive effects of amylase, lysozyme, Ca ions, and low pH on adhesion and aggregation abilities were found. These findings may be useful for selecting probiotic strains for oral health and the development of probiotic products.
Article
Biotechnology & Applied Microbiology
Bingyong Mao, Qunran Xiang, Xin Tang, Qiuxiang Zhang, Xiaoming Liu, Jianxin Zhao, Shumao Cui, Hao Zhang
Summary: This study found that Lactobacillus reuteri CCFM1175 and Lactobacillus paracasei CCFM1176 can effectively prevent CAP-induced intestinal injury and improve gastrointestinal health. By regulating the expression of TRPV1, increasing the level of short-chain fatty acids, and modulating the composition of gut microbiota, these two strains of lactic acid bacteria improve intestinal structure, reduce inflammation, and enhance anti-inflammatory capacity.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Geriatrics & Gerontology
Hye-Yeon Lee, Ji-Hyeon Lee, Seung Hyung Kim, Su-Yeon Jo, Kyung-Jin Min
Summary: This study evaluated the anti-aging effects of Lactobacillus reuteri on the lifespan and physiology of fruit flies. It found that L. reuteri significantly increased the mean lifespan of fruit flies without affecting reproductive output, food intake, or locomotor activity. The study suggests that the longevity effect of L. reuteri is mediated by the reduction of the insulin/IGF-1 signaling pathway and the action of reuterin.
Review
Nutrition & Dietetics
Ameer Al-Hadidi, Jason Navarro, Steven D. Goodman, Michael T. Bailey, Gail E. Besner
Summary: Necrotizing enterocolitis (NEC) is a devastating disease mainly found in premature infants, associated with gastrointestinal dysbiosis. Probiotics have been proposed as a new avenue for therapy, with a novel enterally delivered formulation showing promise in experimental models of NEC.
Article
Geriatrics & Gerontology
Hye-Yeon Lee, Ji-Hyeon Lee, Seung Hyung Kim, Su-Yeon Jo, Kyung-Jin Min
Summary: This study found that L. reuteri has anti-aging effects and can significantly extend the average lifespan of fruit flies. Furthermore, the effects of L. reuteri do not affect the reproductive output, food intake, or locomotor activity of fruit flies. The results suggest that the anti-aging effects of L. reuteri are mediated by the reduction of the insulin/IGF-1 signaling pathway and the action of reuterin.
Article
Biochemistry & Molecular Biology
Fuli Zheng, Zhi Wang, Catherine Stanton, R. Paul Ross, Jianxin Zhao, Hao Zhang, Bo Yang, Wei Chen
Summary: In this study, it was found that strains of L. reuteri and L. rhamnosus significantly slowed weight gain in mice, alleviated blood glucose and lipid disorders, tissue damage, and gut microbiota disorders, produced SCFAs to induce satiety hormones, inhibit food intake, and increase satiety, ultimately improving metabolic syndrome.
Article
Biochemistry & Molecular Biology
Yizhi Zhang, Jinglu Hu, Xingshuang Song, Jing Dai, Ziyan Tang, Guiyu Huang, Wencheng Jiao, Yanping Wu, Chenyun Wang, Lina Du, Yiguang Jin
Summary: This study demonstrates that supplementation of probiotics can improve the gut microenvironment and alleviate the cognitive impairment caused by radiation-induced brain injury (RIBI). Microcapsules containing Lactobacillus reuteri (L. reuteri) were prepared, which significantly enhanced the survival of L. reuteri in the harsh stomach environment. The treatment with L. reuteri microcapsules improved the behavior of RIBI mice and reduced pathological damage in the hippocampus and intestines, as well as decreased the levels of TNF-alpha and IL-6.
Article
Agriculture, Multidisciplinary
Meng-Xin Hu, Fei He, Ya-Xin Guo, Li-Zhen Mo, Xuan Zhu
Summary: This study compares the differences between probiotic biofilms and planktonic cells in pathogen inhibition and microbiota remodeling. The results show that probiotic biofilms are more effective in modulating the microbiota and producing short-chain fatty acids than planktonic cells.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2022)
Article
Multidisciplinary Sciences
Yi-Wei Kuo, Shih-Hung Hsieh, Jui-Fen Chen, Cheng-Ruei Liu, Ching-Wei Chen, Yu-Fen Huang, Hsieh-Hsun Ho
Summary: The study identified Lactobacillus reuteri strain TSR332 and Lactobacillus fermentum strain TSF331 as potential functional probiotic strains for controlling the development of hyperuricemia. These strains showed strong assimilation of purines in vitro, leading to significant reduction of serum UA levels in hyperuricemic rats in vivo.
Article
Agriculture, Dairy & Animal Science
Matteo Dell'Anno, Maria Luisa Callegari, Serena Reggi, Valentina Caprarulo, Carlotta Giromini, Ambra Spalletta, Simona Coranelli, Carlo Angelo Sgoifo Rossi, Luciana Rossi
Summary: This study assessed the effects of Lactobacillus plantarum and Lactobacillus reuteri on in-feed supplementation in weaned piglets, showing that these probiotics can effectively reduce diarrhoea occurrence and serve as interesting functional additives to prevent antibiotic overuse.
Article
Microbiology
Sarayu Bhogoju, Collins N. Khwatenge, Thyneice Taylor-Bowden, Gabriel Akerele, Boniface M. Kimathi, Joseph Donkor, Samuel N. Nahashon
Summary: The study suggests that Lactobacillus reuteri and Streptomyces coelicolor either separately or in combination have the potential to serve as probiotics in chickens, leading to improvements in body weight gain, feed consumption, and feed conversion ratios.
Article
Nutrition & Dietetics
Qianqian Wang, Yufeng He, Xiu Li, Ting Zhang, Ming Liang, Gang Wang, Jianxin Zhao, Hao Zhang, Wei Chen
Summary: Cardiovascular disease, mainly caused by atherosclerosis, is one of the leading causes of morbidity and mortality worldwide. Hypercholesterolemia and hyperlipidemia are the major risk factors for the development of atherosclerosis. Lowering serum cholesterol and triglyceride levels is considered an effective strategy in preventing atherosclerotic cardiovascular disease. The gut microbiota dysbiosis has been associated with various diseases, and probiotic intervention has shown potential in preventing or treating certain diseases. This study demonstrated that treatment with Lactobacillus reuteri CCFM8631 reduced cholesterol levels and improved gut microbiota composition, leading to the alleviation of hypercholesterolemia.
Article
Biotechnology & Applied Microbiology
Nuntiya Pahumunto, Gunnar Dahlen, Rawee Teanpaisan
Summary: This study aimed to characterize the potential probiotic properties of strains from various sources for use in swine feeding. The results showed that strains from different sources exhibited probiotic properties, including inhibition against swine pathogens, adhesion capacity to swine enterocytes, anti-adhesion of pathogens to swine enterocytes, and modulation of innate immunity.
PROBIOTICS AND ANTIMICROBIAL PROTEINS
(2023)
Article
Chemistry, Multidisciplinary
Irina-Georgeta Sufaru, Luminita Lazar, Dorina-Cerasella Sincar, Maria-Alexandra Martu, Liliana Pasarin, Elena-Odette Luca, Ada Stefanescu, Eliza-Maria Froicu, Sorina-Mihaela Solomon
Summary: This study evaluated the clinical effects of L.reuteri DSM 17938 as an adjunctive therapy and found that it significantly improved the clinical parameters of severe periodontitis patients.
APPLIED SCIENCES-BASEL
(2022)
Article
Biology
Zuzana Kissova, Ludmila Tkacikova, Dagmar Mudronova, Mangesh R. Bhide
Summary: The gastrointestinal tract is the largest and most complex component of the immune system, and each component influences the production and regulation of cytokines secreted by intestinal epithelial cells. This study found that the probiotic strain L. reuteri and its exopolysaccharide EPS have immunoregulatory effects on porcine intestinal-epithelial cells infected with Salmonella Typhimurium. The findings suggest that L. reuteri can stimulate innate immune-cell response, modulate inflammatory activities, and affect the expression of Toll-like receptors in the IPEC-J2 cell line.