Article
Microbiology
Weimin Wang, Yukun Zhang, Xiaoxue Zhang, Chong Li, Lvfeng Yuan, Deyin Zhang, Yuan Zhao, Xiaolong Li, Jiangbo Cheng, Changchun Lin, Liming Zhao, Jianghui Wang, Dan Xu, Xiangpeng Yue, Wanhong Li, Xiuxiu Wen, Zhihua Jiang, Xuezhi Ding, Ghasem Hosseini Salekdeh, Fadi Li
Summary: This study reveals the reciprocal interplay among host genetic variations, the rumen microbiota, and the body weight traits of sheep. The findings provide insights into the diverse microbiota characteristics of the rumen and may help in designing precision microbiota management strategies for controlling and manipulating the sheep rumen microbiota to increase productivity.
Article
Microbiology
Jianghui Wang, Yukun Zhang, Xiaojuan Wang, Fadi Li, Deyin Zhang, Xiaolong Li, Yuan Zhao, Liming Zhao, Dan Xu, Jiangbo Cheng, Wenxin Li, Changchun Lin, Xiaobin Yang, Rui Zhai, Xiwen Zeng, Panpan Cui, Zongwu Ma, Jia Liu, Xiaoxue Zhang, Weimin Wang
Summary: This study investigated the relationship between rumen microbiota and mutton marbling grade. The results showed significant differences in intramuscular fat content among different marbling grades, which were correlated with VFAs profiling. The abundance of one bacterial taxon (Kandleria) was higher in high marbling sheep, while two taxa (Pseudobutyrivibrio and Monoglobus) were overrepresented in medium marbling sheep. The main intramuscular fat deposition pathway was associated with PPAR fatty acid synthesis.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Y. K. Zhang, X. X. Zhang, F. D. Li, C. Li, G. Z. Li, D. Y. Zhang, Q. Z. Song, X. L. Li, Y. Zhao, W. M. Wang
Summary: The rumen microbiota in sheep is associated with residual feed intake (RFI), with low-RFI sheep exhibiting a more abundant and diverse microbiome.
Article
Agriculture, Dairy & Animal Science
Weibing Lv, Xiu Liu, Yuzhu Sha, Hao Shi, Hong Wei, Yuzhu Luo, Jiqing Wang, Shaobin Li, Jiang Hu, Xinyu Guo, Xiaoning Pu
Summary: The Qinghai-Tibet Plateau presents unique challenges to the survival of livestock due to its high altitude, low oxygen levels, and imbalances in forage supply. Through adjusting amino acid and energy metabolism pathways, as well as balancing the rumen core microbiota, Tibetan sheep are able to better adapt to the harsh environment. The rumen fermentation characteristics and microbiota of Tibetan sheep vary in different months, highlighting the importance of metabolic pathways in energy utilization and adaptation.
Article
Agriculture, Dairy & Animal Science
Jiangbo Cheng, Xiaoxue Zhang, Dan Xu, Deyin Zhang, Yukun Zhang, Qizhi Song, Xiaolong Li, Yuan Zhao, Liming Zhao, Wenxin Li, Jianghui Wang, Bubo Zhou, Changchun Lin, Xiaobin Yang, Rui Zhai, Panpan Cui, Xiwen Zeng, Yongliang Huang, Zongwu Ma, Jia Liu, Weimin Wang
Summary: This study compared the differences in rumen microbes of different sheep breeds, identified key biomarkers associated with important economic traits of sheep, and found a link between sheep rumen microbes and the differential traits of different breeds. These findings provide a new idea for sheep trait improvement.
JOURNAL OF ANIMAL SCIENCE
(2022)
Article
Agriculture, Dairy & Animal Science
Yukun Zhang, Xiaoxue Zhang, Fadi Li, Chong Li, Deyin Zhang, Xiaolong Li, Yuan Zhao, Weimin Wang
Summary: In modern sheep production systems, efforts are being made to reduce fat deposition costs by altering nutrient use to produce leaner carcasses. Limited research has been done on the effect of rumen microbiome on fat deposition, but this study identified variations in microbial populations in the rumen among sheep with different fat deposition phenotypes, which could help in developing strategies to manipulate rumen microbiota for improved production performance. Extensive study of sheep rumen microbiota has been conducted, but their role in regulating fat deposition remains unclear. This study aimed to identify correlations between fat deposition-related phenotypes and the impact of microbiota on changes in body fat accumulation, identifying 29 ruminal bacteria that may be key drivers of different fat deposition levels.
Article
Microbiology
Xuejiao Yin, Shoukun Ji, Chunhui Duan, Peizhi Tian, Sisi Ju, Hui Yan, Yingjie Zhang, Yueqin Liu
Summary: The rumen microbiota plays a crucial role in the health and growth performance of the host animal by fermenting ingested feed. Age-related changes in the rumen bacteria impact blood metabolite levels, ruminal fermentation, and microbial community functions. There is a degree of plasticity in the rumen bacterial community during the first 20 days of post-natal development in lambs, providing an opportunity for interventions to improve rumen fermentation and growth performance.
FRONTIERS IN MICROBIOLOGY
(2021)
Article
Agriculture, Dairy & Animal Science
W. Zhu, Z. Su, W. Xu, H. X. Sun, J. F. Gao, D. F. Tu, C. H. Ren, Z. J. Zhang, H. G. Cao
Summary: The supplementation of garlic skin improved growth performance and volatile fatty acid concentration in lambs, with significant changes in ruminal bacterial composition and metabolite concentrations. However, it did not significantly affect alpha-diversity indices in rumen microbes. Garlic skin supplementation altered pathways related to pyrimidine metabolism, purine metabolism, and vitamin B6 metabolism, indicating its impact on rumen fermentation.
Article
Biotechnology & Applied Microbiology
Yi Xiong, Xin Wang, Xiaomei Li, Linna Guo, Fuyu Yang, Kuikui Ni
Summary: This study investigated the impact of the woody forage paper mulberry on the rumen microbiota. The results showed that feeding paper mulberry or paper mulberry silage did not significantly affect rumen fermentation products and microbial communities compared to high-protein alfalfa silage. The study suggests that paper mulberry, especially in the form of silage, could be a potential alternative to alfalfa in animal feeding strategies.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2023)
Article
Microbiology
Shiqin Wang, Jianmin Chai, Guohong Zhao, Naifeng Zhang, Kai Cui, Yanliang Bi, Tao Ma, Yan Tu, Qiyu Diao
Summary: Early weaning leads to a significant decrease in rumen microbiota richness and diversity in the short term, but is associated with weaning stress to some extent.
Article
Agriculture, Dairy & Animal Science
Jiao Wang, Long Cheng, Abdul Shakoor Chaudhry, Hassan Khanaki, Imtiaz H. R. Abbasi, Yi Ma, Farzana Abbasi, Xuefeng Guo, Sujiang Zhang
Summary: This study investigated the effects of alfalfa-sweet sorghum mixed silages on the blood and rumen status, as well as rumen microbiota of sheep. The results showed that including 60% alfalfa in the mixed silage had the most positive impact on serum antioxidant capacity, dry matter intake, rumen fermentation, and cellulolytic bacteria abundance in Karakul lambs. These findings contribute to the understanding and promotion of suitable mixtures of alfalfa-sweet sorghum silage in animal production.
Article
Biochemistry & Molecular Biology
Shujie Li, Hanfang Zeng, Changjian Wang, Zhaoyu Han
Summary: This experiment evaluated the effects of methionine hydroxy analog (MHA) on gas production, rumen fermentation parameters, and rumen microbiota. Two different MHA, HMBi and MHA-Ca, were tested in vitro. The results showed that both HMBi and MHA-Ca increased cumulative gas production. The HMBi and MHA-Ca groups had higher volatile fatty acids, microbial protein concentration, acetate, and acetate to propionate ratio, and lower NH3-N concentrations compared to the Control group. The HMBi group also had a different composition of microbiota at the phylum and genus levels. Overall, MHA significantly affected gas production, fermentation parameters, and microbiota composition in sheep.
Article
Microbiology
Paul E. Smith, Alan K. Kelly, David A. Kenny, Sinead M. Waters
Summary: This study aimed to investigate the relationship between the rumen microbiota and residual methane emissions (RME) in finishing beef cattle. The results showed that animals with low RME had higher relative abundances of lactic-acid-producing bacteria and Selenomonas, and lower proportions of Pseudobutyrivibrio, Butyrivibrio, and Mogibacterium in their rumen. Within the rumen methanogen community, low RME animals had increased abundances of Methanosphaera and Methanobrevibacter RO clade. Furthermore, the relative abundances of Intestinibaculum and Olsenella were negatively correlated with RME and positively correlated with ruminal propionate.
FRONTIERS IN MICROBIOLOGY
(2022)
Article
Agriculture, Dairy & Animal Science
Meinan Chang, Fengtao Ma, Jingya Wei, Junhao Liu, Xuemei Nan, Peng Sun
Summary: This study investigated the effects of live and autoclaved Bacillus subtilis natto on ruminal microbiota in vitro using 16S rRNA gene sequencing. It was found that supplementation with live B. subtilis natto improved ruminal NH3-N and propionate concentrations, indicating that live bacteria were more effective than autoclaved ones for promoting ruminal fermentation. The research provides new insights for the precise utilization of Bacillus subtilis natto in dairy rations.
Article
Environmental Sciences
Lu-xi Lin, Qin-qin Cao, Chao-dong Zhang, Ting-ting Xu, Ke Yue, Qinghao Li, Fang Liu, Xuebing Wang, Hai-ju Dong, Shu-cheng Huang, Fu-chun Jian
Summary: This study investigated the effects of AFB1 on the testes of sheep and found that AFB1 can cause testicular damage and dysfunction. The mechanisms involved rumen dysbacteriosis, testicular oxidative stress, and apoptosis.
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
(2022)
Article
Veterinary Sciences
D. Borkent, R. J. M. Reardon, G. McLachlan, L. Glendinning, P. M. Dixon
EQUINE VETERINARY JOURNAL
(2020)
Article
Agriculture, Dairy & Animal Science
Mayumi Fujiwara, Marie Haskell, Alastair Macrae, Kenny Rutherford
JOURNAL OF DAIRY RESEARCH
(2019)
Article
Biotechnology & Applied Microbiology
Cosmin Chintoan-Uta, Trong Wisedchanwet, Laura Glendinning, Abi Bremner, Androniki Psifidi, Lonneke Vervelde, Kellie Watson, Mick Watson, Mark P. Stevens
APPLIED AND ENVIRONMENTAL MICROBIOLOGY
(2020)
Article
Agriculture, Dairy & Animal Science
Mayumi Fujiwara, Marie J. Haskell, Alastair I. Macrae, Kenneth M. D. Rutherford
Editorial Material
Biotechnology & Applied Microbiology
Eric W. F. W. Alton, A. Christopher Boyd, Jane C. Davies, Deborah R. Gill, Uta Griesenbach, Tracy E. Harman, Stephen Hyde, Gerry McLachlan
HUMAN GENE THERAPY
(2020)
Article
Biochemical Research Methods
J. Lima, T. Manning, K. M. Rutherford, E. T. Baima, R. J. Dewhurst, P. Walsh, R. Roehe
Summary: Environmental microbiome studies rely on bioinformatics tools such as MG-RAST and QIIME2 to characterize the taxonomic composition of samples. Comparing the outcomes from these tools showed differences in microbial profiles at different taxonomic levels, with QIIME2 identifying more taxa at the phylum level and showing higher evenness and richness at the family level. Discriminant analyses revealed differences in significant genera between the pipelines, impacting downstream analyses and biomarker identification.
JOURNAL OF MICROBIOLOGICAL METHODS
(2021)
Article
Agronomy
Mark F. Hansen, Emma M. Baxter, Kenneth M. D. Rutherford, Agnieszka Futro, Melvyn L. Smith, Lyndon N. Smith
Summary: This research demonstrates that the impact of increased stress on animal welfare can be identified through frontal images of animals, paving the way for developing an automated system to improve animal welfare in precision livestock farming.
Article
Agriculture, Dairy & Animal Science
Laura Glendinning, Cosmin Chintoan-Uta, Mark P. Stevens, Mick Watson
Summary: The study demonstrated that successful cecal microbiota transplantation can promote a richer and more diverse gut microbiota in chickens, indicating that stable transfer of cecal microbiota between different chicken lines is achievable.
Article
Biotechnology & Applied Microbiology
Gerry McLachlan, Eric W. F. W. Alton, A. Christopher Boyd, Nora K. K. Clarke, Jane C. C. Davies, Deborah R. R. Gill, Uta Griesenbach, Jack W. W. Hickmott, Stephen Hyde, Kamran M. M. Miah, Claudia Juarez Molina
Summary: Gene therapy for respiratory diseases has been a subject of research interest since the 1980s, with advancements in vector systems and delivery cargoes offering hope for potential treatment strategies.
HUMAN GENE THERAPY
(2022)
Article
Agriculture, Dairy & Animal Science
N. N. M. Yusof, K. M. D. Rutherford, S. Jarvis, L. Valente, C. M. Dwyer
Summary: This study investigated the effects of housing management changes on the behavior and HPA axis responses of pregnant ewes. The results indicate that indoor housing has greater stress and adaptation difficulties for primiparous ewes.
Article
Microbiology
Tuan Q. Nguyen, Marina Martinez-alvaro, Joana Lima, Marc D. Auffret, Kenneth M. D. Rutherford, Geoff Simm, Richard J. Dewhurst, Eric T. Baima, Rainer Roehe
Summary: Understanding the relationship between social stress and the gastrointestinal microbiota is important for improving animal welfare and health. The study of pig models has implications for human health. A porcine stress model showed changes in the gut microbiome composition due to social stress, leading to decreased growth performance and appetite. Certain bacteria were enriched or depleted in the intestine and feces of stressed pigs. Depletion of certain bacteria is associated with inferior quality of life and depression in humans. Pathogens were also found to be more prevalent in some pigs under stress.
FRONTIERS IN MICROBIOLOGY
(2023)
Article
Biotechnology & Applied Microbiology
Laura Glendinning, Robert D. Stewart, Mark J. Pallen, Kellie A. Watson, Mick Watson
Article
Veterinary Sciences
Karen Jane Bryson, Damien Garrido, Marco Esposito, Gerry McLachlan, Paul Digard, Catherine Schouler, Rodrigo Guabiraba, Sascha Trapp, Lonneke Vervelde
VETERINARY RESEARCH
(2020)
Article
Microbiology
Bruce C. McGorum, Zihao Chen, Laura Glendinning, Hyun S. Gweon, Luanne Hunt, Alasdair Ivens, John A. Keen, R. Scott Pirie, Joanne Taylor, Toby Wilkinson, Gerry McLachlan
Summary: A study of the gastrointestinal mycobiota of grazing horses identified key fungal populations associated with Equine Grass Sickness (EGS), showing higher fungal richness in EGS horses, significant differences in mycobiota structure, and differential abundance of multiple fungal taxa among different groups.