The pro-fibrotic connective tissue growth factor (CTGF/CCN2) correlates with the number of necrotic-regenerative foci in dystrophic muscle

Connective tissue cells expressing fibro/adipogenic progenitor markers increase under chronic damage: relevance in fibroblast-myofibroblast differentiation and skeletal muscle fibrosis

(2016) Osvaldo Contreras et al.   CELL AND TISSUE RESEARCH

Cellular and molecular actions of CCN2/CTGF and its role under physiological and pathological conditions

(2015) Satoshi Kubota et al.   CLINICAL SCIENCE

SMAD3 and SP1/SP3 Transcription Factors Collaborate to Regulate Connective Tissue Growth Factor Gene Expression in Myoblasts in Response to Transforming Growth Factor β

(2015) Gonzalo Córdova et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Inflammasomes: mechanism of action, role in disease and therapeutics

(2015) Haitao Guo et al.   NATURE MEDICINE

CCN family protein 2 (CCN2) promotes the early differentiation, but inhibits the terminal differentiation of skeletal myoblasts

(2014) T. Nishida et al.   JOURNAL OF BIOCHEMISTRY

Andrographolide attenuates skeletal muscle dystrophy in mdx mice and increases efficiency of cell therapy by reducing fibrosis

(2014) Daniel Cabrera et al.   Skeletal Muscle

Inhibition of the angiotensin-converting enzyme decreases skeletal muscle fibrosis in dystrophic mice by a diminution in the expression and activity of connective tissue growth factor (CTGF/CCN-2)

(2013) María Gabriela Morales et al.   CELL AND TISSUE RESEARCH

Modifying muscular dystrophy through transforming growth factor-β

(2013) Ermelinda Ceco et al.   FEBS Journal

Restoration of muscle strength in dystrophic muscle by angiotensin-1-7 through inhibition of TGF-β signalling

(2013) María José Acuña et al.   HUMAN MOLECULAR GENETICS

Reducing CTGF/CCN2 slows down mdx muscle dystrophy and improves cell therapy

(2013) Maria Gabriela Morales et al.   HUMAN MOLECULAR GENETICS

CCN2/CTGF is required for matrix organization and to protect growth plate chondrocytes from cellular stress

(2013) Faith Hall-Glenn et al.   Journal of Cell Communication and Signaling

CCN2: a master regulator of the genesis of bone and cartilage

(2013) Masaharu Takigawa   Journal of Cell Communication and Signaling

Regulation of pancreatic function by connective tissue growth factor (CTGF, CCN2)

(2012) Alyssa Charrier et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Mechanisms of fibrosis: therapeutic translation for fibrotic disease

(2012) Thomas A Wynn et al.   NATURE MEDICINE

Angiotensin II receptor type 1 blockade decreases CTGF/CCN2-mediated damage and fibrosis in normal and dystrophic skeletal muscles

(2011) Claudio Cabello-Verrugio et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Role of transforming growth factor-β1 in the process of fibrosis of denervated skeletal muscle

(2011) Meng Fanbin et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

CTGF/CCN-2 over-expression can directly induce features of skeletal muscle dystrophy

(2011) María Gabriela Morales et al.   JOURNAL OF PATHOLOGY

Ethanol-stimulated differentiated functions of human or mouse hepatic stellate cells are mediated by connective tissue growth factor

(2010) Li Chen et al.   JOURNAL OF HEPATOLOGY

Regulation of pro-inflammatory and pro-fibrotic factors by CCN2/CTGF in H9c2 cardiomyocytes

(2010) Xiaoyu Wang et al.   Journal of Cell Communication and Signaling

Pivotal role of connective tissue growth factor in lung fibrosis: MAPK-dependent transcriptional activation of type I collagen

(2009) Markella Ponticos et al.   ARTHRITIS AND RHEUMATISM

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

CTGF Promotes Inflammatory Cell Infiltration of the Renal Interstitium by Activating NF- B

(2009) E. Sanchez-Lopez et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

(2009) Andrew Leask et al.   Journal of Cell Communication and Signaling

Dynamic Analysis of the Expression of the TGFβ/SMAD2 Pathway and CCN2/CTGF during Early Steps of Tooth Development

(2008) Marcos S. Pacheco et al.   CELLS TISSUES ORGANS

Skeletal muscle cells express the profibrotic cytokine connective tissue growth factor (CTGF/CCN2), which induces their dedifferentiation

(2007) Cecilia Vial et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Cellular and molecular mechanisms of fibrosis

(2007) TA Wynn   JOURNAL OF PATHOLOGY

Connective tissue growth factor is overexpressed in muscles of human muscular dystrophy

(2007) Guilian Sun et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES