PPARα/γ antagonists reverse the ameliorative effects of osthole on hepatic lipid metabolism and inflammatory response in steatohepatitic rats

PPARα/γ agonists and antagonists differently affect hepatic lipid metabolism, oxidative stress and inflammatory cytokine production in steatohepatitic rats

(2015) Yan Zhang et al.   CYTOKINE

Osthole attenuates the development of carrageenan-induced lung inflammation in rats

(2014) Zhipeng Li et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Involvement of hepatic peroxisome proliferator-activated receptor α/γ in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats

(2014) Xi Zhao et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

SREBP-1c overexpression induces triglycerides accumulation through increasing lipid synthesis and decreasing lipid oxidation and VLDL assembly in bovine hepatocytes

(2014) Xinwei Li et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Combination treatment with platycodin D and osthole inhibits cell proliferation and invasion in mammary carcinoma cell lines

(2013) Yiyi Ye et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Resveratrol modulates autophagy and NF-κB activity in a murine model for treating non-alcoholic fatty liver disease

(2013) Lake Li et al.   FOOD AND CHEMICAL TOXICOLOGY

From fatty liver to fibrosis: A tale of “second hit”

(2013) Metin Basaranoglu   WORLD JOURNAL OF GASTROENTEROLOGY

Mechanisms of Disease Progression in NASH

(2012) Brittany N. Bohinc et al.   Clinics in Liver Disease

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Anti-inflammatory mechanism of PPARγ on LPS-induced pulp cells: Role of the ROS removal activity

(2011) Jae-Cheol Kim et al.   ARCHIVES OF ORAL BIOLOGY

Osthol ameliorates fat milk-induced fatty liver in mice by regulation of hepatic sterol regulatory element-binding protein-1c/2-mediated target gene expression

(2011) Rao Du et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Peroxisome proliferator-activated receptor-α activation attenuates 3-nitropropionic acid induced behavioral and biochemical alterations in rats: Possible neuroprotective mechanisms

(2011) Deepak Kumar Bhateja et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Modulation of PPAR-γ by telmisartan protects the heart against myocardial infarction in experimental diabetes

(2010) Sameer Goyal et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Osthole improves alcohol-induced fatty liver in mice by reduction of hepatic oxidative stress

(2010) Jianjun Zhang et al.   PHYTOTHERAPY RESEARCH

Bixin regulates mRNA expression involved in adipogenesis and enhances insulin sensitivity in 3T3-L1 adipocytes through PPARγ activation

(2009) Nobuyuki Takahashi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Activation of PPARα and PPARγ reduces triacylglycerol synthesis in rat hepatoma cells by reduction of nuclear SREBP-1

(2009) Bettina König et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Osthol regulates hepatic PPARα-mediated lipogenic gene expression in alcoholic fatty liver murine

(2009) Fan Sun et al.   PHYTOMEDICINE

Role of peroxisome proliferators-activated receptors in the pathogenesis and treatment of nonalcoholic fatty liver disease

(2008) Eric R Kallwitz et al.   WORLD JOURNAL OF GASTROENTEROLOGY