Oral Administration of the Probiotic Strain Escherichia coli Nissle 1917 Reduces Susceptibility to Neuroinflammation and Repairs Experimental Autoimmune Encephalomyelitis-Induced Intestinal Barrier Dysfunction

Postarrest stalling rather than crawling favors CD8+ over CD4+ T-cell migration across the blood-brain barrier under flow in vitro

(2016) Henriette Rudolph et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxo3 Transcription Factor Drives Pathogenic T Helper 1 Differentiation by Inducing the Expression of Eomes

(2016) Caroline Stienne et al.   IMMUNITY

Respective Roles of Hematopoietic and Nonhematopoietic Nod2 on the Gut Microbiota and Mucosal Homeostasis

(2016) Ziad Alnabhani et al.   INFLAMMATORY BOWEL DISEASES

Microcins mediate competition among Enterobacteriaceae in the inflamed gut

(2016) Martina Sassone-Corsi et al.   NATURE

Alterations of the human gut microbiome in multiple sclerosis

(2016) Sushrut Jangi et al.   Nature Communications

A Natural Variant of the T Cell Receptor-Signaling Molecule Vav1 Reduces Both Effector T Cell Functions and Susceptibility to Neuroinflammation

(2016) Sahar Kassem et al.   PLoS Genetics

Multiple sclerosis patients have a distinct gut microbiota compared to healthy controls

(2016) Jun Chen et al.   Scientific Reports

Microbiota and Autoimmunity: Exploring New Avenues

(2015) Leonid A. Yurkovetskiy et al.   Cell Host & Microbe

Alterations in Intestinal Microbiota Correlate With Susceptibility to Type 1 Diabetes

(2015) Aimon K. Alkanani et al.   DIABETES

Pseudomonas fluorescens Alters the Intestinal Barrier Function by Modulating IL-1β Expression Through Hematopoietic NOD2 Signaling

(2015) Ziad Alnabhani et al.   INFLAMMATORY BOWEL DISEASES

Functional inflammatory profiles distinguish myelin-reactive T cells from patients with multiple sclerosis

(2015) Yonghao Cao et al.   Science Translational Medicine

Immunology of Relapse and Remission in Multiple Sclerosis

(2014) Lawrence Steinman   Annual Review of Immunology

The Microbiome in Inflammatory Bowel Disease: Current Status and the Future Ahead

(2014) Aleksandar D. Kostic et al.   GASTROENTEROLOGY

Intestinal Barrier Dysfunction Develops at the Onset of Experimental Autoimmune Encephalomyelitis, and Can Be Induced by Adoptive Transfer of Auto-Reactive T Cells

(2014) Mehrnaz Nouri et al.   PLoS One

Commensal microbiota regulates T cell fate decision in the gut

(2014) Yukihiro Furusawa et al.   Seminars in Immunopathology

Vitamin D as an Early Predictor of Multiple Sclerosis Activity and Progression

(2014) Alberto Ascherio et al.   JAMA Neurology

Advances in understanding the pathogenesis of autoimmune disorders: focus on chemokines and lymphocyte trafficking

(2013) Iain Comerford et al.   BRITISH JOURNAL OF HAEMATOLOGY

Peripheral education of the immune system by the colonic microbiota

(2013) Kristine A. Kuhn et al.   SEMINARS IN IMMUNOLOGY

Regional Neural Activation Defines a Gateway for Autoreactive T Cells to Cross the Blood-Brain Barrier

(2012) Yasunobu Arima et al.   CELL

Yersinia pseudotuberculosis disrupts intestinal barrier integrity through hematopoietic TLR-2 signaling

(2012) Camille Jung et al.   JOURNAL OF CLINICAL INVESTIGATION

Molecular monitoring of the development of intestinal microbiota in Japanese infants

(2012) H. Tsuji et al.   Beneficial Microbes

Escherichia coli Nissle 1917 (Mutaflor): New Insights into an Old Probiotic Bacterium

(2011) Christoph A. Jacobi et al.   DIGESTIVE DISEASES

Interleukin-10 Signaling in Regulatory T Cells Is Required for Suppression of Th17 Cell-Mediated Inflammation

(2011) Ashutosh Chaudhry et al.   IMMUNITY

Th17 Cells Express Interleukin-10 Receptor and Are Controlled by Foxp3− and Foxp3+ Regulatory CD4+ T Cells in an Interleukin-10-Dependent Manner

(2011) Samuel Huber et al.   IMMUNITY

Interleukin-6 (IL-6) Regulates Claudin-2 Expression and Tight Junction Permeability in Intestinal Epithelium

(2011) Takuya Suzuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination

(2011) Kerstin Berer et al.   NATURE

Zonulin and Its Regulation of Intestinal Barrier Function: The Biological Door to Inflammation, Autoimmunity, and Cancer

(2011) Alessio Fasano   PHYSIOLOGICAL REVIEWS

The ‘hygiene hypothesis’ for autoimmune and allergic diseases: an update

(2010) H. Okada et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

Autoimmune diseases prior to the diagnosis of multiple sclerosis: a population-based case-control study

(2010) A. Langer-Gould et al.   Multiple Sclerosis Journal

Proinflammatory T-cell responses to gut microbiota promote experimental autoimmune encephalomyelitis

(2010) Y. K. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Role of Gut Commensal Microflora in the Development of Experimental Autoimmune Encephalomyelitis

(2009) J. Ochoa-Reparaz et al.   JOURNAL OF IMMUNOLOGY

IL-17 and Th17 cells in human inflammatory diseases

(2009) Pierre Miossec   MICROBES AND INFECTION

A protective function for interleukin 17A in T cell–mediated intestinal inflammation

(2009) William O'Connor Jr et al.   NATURE IMMUNOLOGY

Targeted Epithelial Tight Junction Dysfunction Causes Immune Activation and Contributes to Development of Experimental Colitis

(2008) Liping Su et al.   GASTROENTEROLOGY

The probiotic Escherichia coli strain Nissle 1917 induces γδ T cell apoptosis via caspase- and FasL-dependent pathways

(2008) Claudia Guzy et al.   INTERNATIONAL IMMUNOLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

The genetics of multiple sclerosis: SNPs to pathways to pathogenesis

(2008) Jorge R. Oksenberg et al.   NATURE REVIEWS GENETICS