标题
Macrophage Metabolism As Therapeutic Target for Cancer, Atherosclerosis, and Obesity
作者
关键词
-
出版物
Frontiers in Immunology
Volume 8, Issue -, Pages -
出版商
Frontiers Media SA
发表日期
2017-03-15
DOI
10.3389/fimmu.2017.00289
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- Ornithine decarboxylase regulates M1 macrophage activation and mucosal inflammation via histone modifications
- (2017) Dana M. Hardbower et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Tissue-resident versus monocyte-derived macrophages in the tumor microenvironment
- (2016) Qods Lahmar et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages
- (2016) Evanna L. Mills et al. CELL
- Macrophage Metabolism Controls Tumor Blood Vessel Morphogenesis and Metastasis
- (2016) Mathias Wenes et al. Cell Metabolism
- Itaconate Links Inhibition of Succinate Dehydrogenase with Macrophage Metabolic Remodeling and Regulation of Inflammation
- (2016) Vicky Lampropoulou et al. Cell Metabolism
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Immunoresponsive Gene 1 and Itaconate Inhibit Succinate Dehydrogenase to Modulate Intracellular Succinate Levels
- (2016) Thekla Cordes et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fatty acid oxidation in macrophage polarization
- (2016) Mitsunori Nomura et al. NATURE IMMUNOLOGY
- Emerging concepts of T cell metabolism as a target of immunotherapy
- (2016) Chih-Hao Chang et al. NATURE IMMUNOLOGY
- New insights into the multidimensional concept of macrophage ontogeny, activation and function
- (2016) Florent Ginhoux et al. NATURE IMMUNOLOGY
- The Reactive Oxygen Species in Macrophage Polarization: Reflecting Its Dual Role in Progression and Treatment of Human Diseases
- (2016) Hor-Yue Tan et al. Oxidative Medicine and Cellular Longevity
- Mitochondrial Dysfunction Prevents Repolarization of Inflammatory Macrophages
- (2016) Jan Van den Bossche et al. Cell Reports
- Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma
- (2016) Hweixian Leong Penny et al. OncoImmunology
- Metabolic communication in tumors: a new layer of immunoregulation for immune evasion
- (2016) Ping-Chih Ho et al. Journal for ImmunoTherapy of Cancer
- Enhanced fatty acid oxidation in adipocytes and macrophages reduces lipid-induced triglyceride accumulation and inflammation
- (2015) Maria Ida Malandrino et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Metabolic signatures linked to macrophage polarization: from glucose metabolism to oxidative phosphorylation
- (2015) Lisardo Boscá et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Metabolic control of signalling pathways and metabolic auto-regulation
- (2015) Doriane Lorendeau et al. BIOLOGY OF THE CELL
- M-CSF and GM-CSF Receptor Signaling Differentially Regulate Monocyte Maturation and Macrophage Polarization in the Tumor Microenvironment
- (2015) E. Van Overmeire et al. CANCER RESEARCH
- Metabolic reprogramming in macrophages and dendritic cells in innate immunity
- (2015) Beth Kelly et al. CELL RESEARCH
- Network Integration of Parallel Metabolic and Transcriptional Data Reveals Metabolic Modules that Regulate Macrophage Polarization
- (2015) Abhishek K. Jha et al. IMMUNITY
- Pro-inflammatory Macrophages Sustain Pyruvate Oxidation through Pyruvate Dehydrogenase for the Synthesis of Itaconate and to Enable Cytokine Expression
- (2015) Johannes Meiser et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- MicroRNA-33–dependent regulation of macrophage metabolism directs immune cell polarization in atherosclerosis
- (2015) Mireille Ouimet et al. JOURNAL OF CLINICAL INVESTIGATION
- Immunometabolism governs dendritic cell and macrophage function
- (2015) Luke A.J. O’Neill et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The interaction of anticancer therapies with tumor-associated macrophages
- (2015) Alberto Mantovani et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Fatty acid carbon is essential for dNTP synthesis in endothelial cells
- (2015) Sandra Schoors et al. NATURE
- Metabolic–epigenetic crosstalk in macrophage activation
- (2015) Jeroen Baardman et al. Epigenomics
- PD-1 alters T-cell metabolic reprogramming by inhibiting glycolysis and promoting lipolysis and fatty acid oxidation
- (2015) Nikolaos Patsoukis et al. Nature Communications
- mTORC1-Induced HK1-Dependent Glycolysis Regulates NLRP3 Inflammasome Activation
- (2015) Jong-Seok Moon et al. Cell Reports
- A key role of the mitochondrial citrate carrier (SLC25A1) in TNFα- and IFNγ-triggered inflammation
- (2014) Vittoria Infantino et al. Biochimica et Biophysica Acta-Gene Regulatory Mechanisms
- Metabolic Dysfunction Drives a Mechanistically Distinct Proinflammatory Phenotype in Adipose Tissue Macrophages
- (2014) Mario Kratz et al. Cell Metabolism
- Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines
- (2014) Peter J. Murray et al. IMMUNITY
- Transcriptome-Based Network Analysis Reveals a Spectrum Model of Human Macrophage Activation
- (2014) Jia Xue et al. IMMUNITY
- Metabolic Reprogramming of Macrophages
- (2014) Alex J. Freemerman et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Monocarboxylate Transporter 4 Is Required for Glycolytic Reprogramming and Inflammatory Response in Macrophages
- (2014) Zheng Tan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Plasticity of Macrophage Function during Tumor Progression: Regulation by Distinct Molecular Mechanisms
- (2014) S. K. Biswas et al. JOURNAL OF IMMUNOLOGY
- Metabolism of stromal and immune cells in health and disease
- (2014) Bart Ghesquière et al. NATURE
- Cessation of CCL2 inhibition accelerates breast cancer metastasis by promoting angiogenesis
- (2014) Laura Bonapace et al. NATURE
- Functional polarization of tumour-associated macrophages by tumour-derived lactic acid
- (2014) Oscar R. Colegio et al. NATURE
- Cell-intrinsic lysosomal lipolysis is essential for alternative activation of macrophages
- (2014) Stanley Ching-Cheng Huang et al. NATURE IMMUNOLOGY
- Macrophage: SHIP of Immunity
- (2014) Charles D. Mills et al. Frontiers in Immunology
- Dynamic Aspects of Macrophage Polarization during Atherosclerosis Progression and Regression
- (2014) Michael Peled et al. Frontiers in Immunology
- Metabolic Reprograming in Macrophage Polarization
- (2014) Silvia Galván-Peña et al. Frontiers in Immunology
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- ATP-citrate lyase is essential for macrophage inflammatory response
- (2013) Vittoria Infantino et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity
- (2013) Andrea Casazza et al. CANCER CELL
- Macrophage Regulation of Tumor Responses to Anticancer Therapies
- (2013) Michele De Palma et al. CANCER CELL
- A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors
- (2013) Shahneen K. Sandhu et al. CANCER CHEMOTHERAPY AND PHARMACOLOGY
- Tumor Hypoxia Does Not Drive Differentiation of Tumor-Associated Macrophages but Rather Fine-Tunes the M2-like Macrophage Population
- (2013) D. Laoui et al. CANCER RESEARCH
- Obesity Activates a Program of Lysosomal-Dependent Lipid Metabolism in Adipose Tissue Macrophages Independently of Classic Activation
- (2013) Xiaoyuan Xu et al. Cell Metabolism
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- Inflammatory Monocyte Mobilization Decreases Patient Survival in Pancreatic Cancer: A Role for Targeting the CCL2/CCR2 Axis
- (2013) D. E. Sanford et al. CLINICAL CANCER RESEARCH
- Succinate is an inflammatory signal that induces IL-1β through HIF-1α
- (2013) G. M. Tannahill et al. NATURE
- CSF-1R inhibition alters macrophage polarization and blocks glioma progression
- (2013) Stephanie M Pyonteck et al. NATURE MEDICINE
- Immune-responsive gene 1 protein links metabolism to immunity by catalyzing itaconic acid production
- (2013) A. Michelucci et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Myeloid Krüppel-Like Factor 4 Deficiency Augments Atherogenesis in ApoE −/− Mice—Brief Report
- (2012) Nikunj Sharma et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Distribution of macrophage polarization markers in human atherosclerosis
- (2012) J. Lauran Stöger et al. ATHEROSCLEROSIS
- Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1
- (2012) Joseph E. Qualls et al. Cell Host & Microbe
- The Sedoheptulose Kinase CARKL Directs Macrophage Polarization through Control of Glucose Metabolism
- (2012) Arvand Haschemi et al. Cell Metabolism
- Orchestration of Metabolism by Macrophages
- (2012) Subhra K. Biswas et al. Cell Metabolism
- Interleukin-13 protects from atherosclerosis and modulates plaque composition by skewing the macrophage phenotype
- (2012) Larissa Cardilo-Reis et al. EMBO Molecular Medicine
- Mechanisms of triglyceride accumulation in activated macrophages
- (2012) Kenneth R. Feingold et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Prognostic Significance of Tumor-Associated Macrophages in Solid Tumor: A Meta-Analysis of the Literature
- (2012) Qiong-wen Zhang et al. PLoS One
- Aerobic Glycolysis: Meeting the Metabolic Requirements of Cell Proliferation
- (2011) Sophia Y. Lunt et al. Annual Review of Cell and Developmental Biology
- The mitochondrial citrate carrier: a new player in inflammation
- (2011) Vittoria Infantino et al. BIOCHEMICAL JOURNAL
- Reversal of Hyperlipidemia With a Genetic Switch Favorably Affects the Content and Inflammatory State of Macrophages in Atherosclerotic Plaques
- (2011) Jonathan E. Feig et al. CIRCULATION
- NR4A1 (Nur77) Deletion Polarizes Macrophages Toward an Inflammatory Phenotype and Increases Atherosclerosis
- (2011) Richard N. Hanna et al. CIRCULATION RESEARCH
- TLR signalling augments macrophage bactericidal activity through mitochondrial ROS
- (2011) A. Phillip West et al. NATURE
- HDL promotes rapid atherosclerosis regression in mice and alters inflammatory properties of plaque monocyte-derived cells
- (2011) J. E. Feig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of fatty acid oxidation by etomoxir impairs NADPH production and increases reactive oxygen species resulting in ATP depletion and cell death in human glioblastoma cells
- (2010) Lisa S. Pike et al. BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS
- Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes
- (2010) K. Movahedi et al. CANCER RESEARCH
- Macrophage Diversity Enhances Tumor Progression and Metastasis
- (2010) Bin-Zhi Qian et al. CELL
- Control of Macrophage Activation and Function by PPARs
- (2010) Ajay Chawla CIRCULATION RESEARCH
- Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
- (2010) Aliki Kosteli et al. JOURNAL OF CLINICAL INVESTIGATION
- Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation
- (2010) J.-C. Rodriguez-Prados et al. JOURNAL OF IMMUNOLOGY
- Induction of fatty acid synthesis is a key requirement for phagocytic differentiation of human monocytes
- (2010) Josef Ecker et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pharmacologic inhibition of fatty acid oxidation sensitizes human leukemia cells to apoptosis induction
- (2009) Ismael Samudio et al. JOURNAL OF CLINICAL INVESTIGATION
- ATP-Citrate Lyase Links Cellular Metabolism to Histone Acetylation
- (2009) K. E. Wellen et al. SCIENCE
- Arginase I Induction by Modified Lipoproteins in Macrophages: A Peroxisome Proliferator-Activated Receptor-γ/δ-Mediated Effect that Links Lipid Metabolism and Immunity
- (2008) Alejandro Gallardo-Soler et al. MOLECULAR ENDOCRINOLOGY
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