Anti-GPC3-CAR T Cells Suppress the Growth of Tumor Cells in Patient-Derived Xenografts of Hepatocellular Carcinoma

Redirecting T Cells to Glypican-3 with 4-1BB Zeta Chimeric Antigen Receptors Results in Th1 Polarization and Potent Antitumor Activity

(2017) Wenpeng Li et al.   HUMAN GENE THERAPY

Heterogeneity of CD34 and CD38 expression in acute B lymphoblastic leukemia cells is reversible and not hierarchically organized

(2016) Zhiwu Jiang et al.   Journal of Hematology & Oncology

Epithelial-to-mesenchymal plasticity of cancer stem cells: therapeutic targets in hepatocellular carcinoma

(2016) Aparna Jayachandran et al.   Journal of Hematology & Oncology

Novel patient-derived xenograft and cell line models for therapeutic testing of pediatric liver cancer

(2016) Beatrice Bissig-Choisat et al.   JOURNAL OF HEPATOLOGY

T Cells Engineered to Express a T-Cell Receptor Specific for Glypican-3 to Recognize and Kill Hepatoma Cells In Vitro and in Mice

(2015) Christina Dargel et al.   GASTROENTEROLOGY

Loss of Angiopoietin-like 7 diminishes the regeneration capacity of hematopoietic stem and progenitor cells

(2015) Yiren Xiao et al.   Journal of Hematology & Oncology

Quantitative evaluation of the immunodeficiency of a mouse strain by tumor engraftments

(2015) Wei Ye et al.   Journal of Hematology & Oncology

4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors

(2015) Adrienne H Long et al.   NATURE MEDICINE

CD4+CD25+CD127low Regulatory T Cells Play Predominant Anti-Tumor Suppressive Role in Hepatitis B Virus-Associated Hepatocellular Carcinoma

(2015) Shreya Sharma et al.   Frontiers in Immunology

Development of T Cells Redirected to Glypican-3 for the Treatment of Hepatocellular Carcinoma

(2014) H. Gao et al.   CLINICAL CANCER RESEARCH

Multifactorial T-cell Hypofunction That Is Reversible Can Limit the Efficacy of Chimeric Antigen Receptor-Transduced Human T cells in Solid Tumors

(2014) E. K. Moon et al.   CLINICAL CANCER RESEARCH

Establishment and Characterization of 7 Novel Hepatocellular Carcinoma Cell Lines from Patient-Derived Tumor Xenografts

(2014) Hong Xin et al.   PLoS One

Anti-PD-1 Antibody Therapy Potently Enhances the Eradication of Established Tumors By Gene-Modified T Cells

(2013) L. B. John et al.   CLINICAL CANCER RESEARCH

A Hepatocellular Carcinoma 5-Gene Score Associated With Survival of Patients After Liver Resection

(2013) Jean–Charles Nault et al.   GASTROENTEROLOGY

Chimeric antigen receptor-engineered T cells for cancer immunotherapy: progress and challenges

(2013) Ethan Q Han et al.   Journal of Hematology & Oncology

Hepatocellular Carcinoma

(2013) Andrew J. Page et al.   Surgical Oncology Clinics of North America

Patient-derived tumour xenografts as models for oncology drug development

(2012) John J. Tentler et al.   Nature Reviews Clinical Oncology

Patient-derived human tumour tissue xenografts in immunodeficient mice: a systematic review

(2010) Ketao Jin et al.   Clinical & Translational Oncology

Tumour-experienced T cells promote NK cell activity through trogocytosis of NKG2D and NKp46 ligands

(2009) Carolina I Domaica et al.   EMBO REPORTS

PD-1 and Its Ligands in Tolerance and Immunity

(2008) Mary E. Keir et al.   Annual Review of Immunology