Review
Biotechnology & Applied Microbiology
Tatenda Yemeke, Hui-Han Chen, Sachiko Ozawa
Summary: Antimicrobial resistance (AMR) poses a global public health threat with significant morbidity, mortality, and economic costs. Vaccines can help combat AMR by reducing resistant disease cases and overall antibiotic use. However, there is limited economic evidence demonstrating the AMR-related value of vaccines, hindering their utilization and investment. More research on the cost-effectiveness and economic value of vaccines in controlling AMR is needed to inform resource allocation decisions and development priorities.
HUMAN VACCINES & IMMUNOTHERAPEUTICS
(2023)
Article
Immunology
Damon J. A. Toth, Matthew H. Samore, Richard E. Nelson
Summary: A mathematical model was developed to evaluate the effects of two hypothetical antibiotics targeting carbapenem-resistant Enterobacteriaceae (CRE) in long-term acute care hospital inpatients, showing that decolonizing antibiotics can be more effective and cost-saving compared to usual care and treatment antibiotics in preventing infections and deaths.
CLINICAL INFECTIOUS DISEASES
(2021)
Article
Agriculture, Dairy & Animal Science
T. V. Silva, E. B. de Oliveira, J. Perez-Baez, C. A. Risco, R. C. Chebel, F. Cunha, R. Daetz, J. E. P. Santos, F. S. Lima, K. C. Jeong, K. N. Galvao
Summary: Treating dairy cows with metritis using ceftiofur-free acid resulted in higher treatment costs but increased pregnancy rates and decreased culling, leading to improved profitability compared to leaving them untreated. Metritis caused economic losses, but treating with ceftiofur reduced losses by improving fertility, reducing culling and replacement costs, and minimizing milk yield losses.
JOURNAL OF DAIRY SCIENCE
(2021)
Article
Agronomy
Dun-Chun He, Yan-Li Ma, Zhuan-Zhuan Li, Chang-Sui Zhong, Zhao-Bang Cheng, Jiasui Zhan
Summary: The study found that increasing agricultural diversity through crop rotations, especially potato-rice rotation, significantly improves social, economic, and ecological benefits in rice production. However, rationalizing fertilizer application is necessary to enhance resource and investment efficiency. Internalizing externalities and incentivizing farmers to adopt crop rotation methods for sustainable rice production are important strategies proposed in the research.
Article
Economics
Ashwin Rode
Summary: Analyzing the impact of rent-seeking behavior on firm permit allocation using the UK's CO2 Emissions Trading Scheme, it was found that financial connections to members of the House of Commons strongly predict post-appeal allocation. Even after controlling for various factors, such connections were associated with a significant increase in actual permit allocation. The estimated welfare loss from rent-seeking was over 100 million euros, a substantial amount compared to firms' abatement costs.
ENVIRONMENTAL & RESOURCE ECONOMICS
(2021)
Article
Public, Environmental & Occupational Health
Akashdeep Singh Chauhan, Deepshikha Sharma, Abha Mehndiratta, Nidhi Gupta, Basant Garg, Amneet P. Kumar, Shankar Prinja
Summary: This study assessed the accuracy of results generated from adaptive HTA approaches for economic evaluation specific to the Indian context. The findings showed significant variations in adapted cost estimates while quality-adjusted life-years did not differ much. There is a need to interpret findings from aHTA methods with caution and develop more robust approaches for cost adjustment in the future.
Article
Endocrinology & Metabolism
Nikolaos Kotsopoulos, Mark P. Connolly, Michael Willis, Andreas Nilsson, Asa Ericsson, James Baker-Knight
Summary: This study estimated the fiscal burden for taxpayers in Sweden associated with type 2 diabetes and its complications. It found that failure to meet HbA1c targets resulted in significant tax revenue losses and excess disability payments for the government.
DIABETES OBESITY & METABOLISM
(2022)
Review
Dentistry, Oral Surgery & Medicine
Falk Schwendicke, Sascha Rudolf Herbst
Summary: This review introduces the main concepts of health economic analysis, systematically reviews the existing economic literature on endodontic treatments, and suggests further action for the community. The identified evidence on the health economics of endodontic therapies is limited and has some limitations. However, maintaining pulpal vitality is preferred over root canal treatment for cost-effectiveness, retaining teeth is usually more cost-effective than extraction and replacement, and endodontic retreatment may be clinically indicated but not always cost-effective and should be carefully considered.
INTERNATIONAL ENDODONTIC JOURNAL
(2023)
Article
Green & Sustainable Science & Technology
Muhammad Shahid, Kafait Ullah, Kashif Imran, Arshad Mahmood, Maarten Arentsen
Summary: Several planning problems in the power sector of Pakistan, including gradual reliance on expensive energy sources, supply shortages, circular debt, have hindered the growth of allied economic sectors. Using the LEAP system, this study simulated Pakistan's electrical system and analyzed different scenarios based on technoeconomic and environmental parameters. The study suggests prioritizing the use of indigenous and renewable energy resources to alleviate the energy crisis.
SUSTAINABLE ENERGY TECHNOLOGIES AND ASSESSMENTS
(2021)
Article
Thermodynamics
Hermas Abudu, Xiangyu Cai, Boqiang Lin
Summary: The study found that the upstream petroleum industry negatively impacts the livelihoods of fishermen, farmers, and other community residents in Ghana, while also adversely affecting the economic, social, and environmental well-being of coastal dwellers. Despite this, the industry also contributes positively to social and economic benefits.
Article
Economics
Monika Banaszewska
Summary: The study suggests that municipalities governed by politically weak mayors tend to forgo more tax revenues, but the impact on municipal revenues is limited, indicating that preferential tax policies are more of a political tool. Mayors who offer more tax reductions to natural persons are less popular.
Article
Chemistry, Multidisciplinary
Yanchen Liu, Haoning Gong, Zhiwei Wang, Chengqian Yuan, Jianren Lu, Xuehai Yan
Summary: A new antimicrobial peptide hydrogel based on supramolecular self-assembly is developed, which exhibits strong antimicrobial activity against resistant strains and high cytocompatibility. The hydrogel also has immunoregulative activity and shows promising potential in treating skin abscess disease caused by methicillin-resistant Staphylococcus aureus infection. This study not only provides insights into the design of supramolecular AMP hydrogels and their immune-related antimicrobial actions, but also advances the development of self-assembly peptide platforms to combat antimicrobial resistant infections.
ADVANCED FUNCTIONAL MATERIALS
(2023)
Article
Infectious Diseases
German Penalva, Paloma Crespo-Robledo, Mari Molvik, Antonio Lopez-Navas, Oliver Kacelnik, Jose Miguel Cisneros
Summary: This study aimed to investigate the feasibility and scalability of a quarterly surveillance system for antimicrobial resistance (AMR) and antimicrobial use (AMU) in the European Union/European Economic Area (EU/EEA). The study found significant variation in AMU among the participating partners, and identified barriers and needs for implementing the surveillance system.
Article
Biochemistry & Molecular Biology
Paolo Stincone, Flavio Fonseca Veras, Giuseppe Micalizzi, Danilo Donnarumma, Gaetano Vitale Celano, Daniel Petras, Maria de Angelis, Luigi Mondello, Adriano Brandelli
Summary: This study investigated the effect of antimicrobial peptides on L. monocytogenes using mass spectrometry-based lipidomics and proteomics. The results showed that the treatment with antimicrobial peptides caused changes in lipid and protein profiles, affecting the biofilm formation.
CELLULAR AND MOLECULAR LIFE SCIENCES
(2022)
Review
Food Science & Technology
Mrinal Samtiya, Karl R. Matthews, Tejpal Dhewa, Anil Kumar Puniya
Summary: Antimicrobial resistance (AMR) is a global concern that can negatively impact human health, particularly in low- and middle-income countries. The contamination of food with antimicrobial-resistant bacteria and/or resistance genes can occur at any stage, from production to retail. Preventing the spread of foodborne pathogens and ensuring food safety and security require national and international efforts. It is crucial to control antibiotic use in both animal and crop agriculture to mitigate the risk of AMR bacteria in humans.