Article
Biochemical Research Methods
Yancheng Wang, Hemin Pan, Deqing Mei, Chengyao Xu, Wanyu Weng
Summary: This article presents a novel design of a tri-directional symmetrical acoustic tweezers device that enables precise manipulation of linear, clockwise, and anticlockwise trajectories of microparticles. By adjusting the input electric signals and the fluid's viscosity, the device is able to accurately modulate the motion parameters and manipulate various forms of microparticles as well as brine shrimp egg cells.
Article
Physics, Multidisciplinary
Hao Ge, Xiang-Yuan Xu, Le Liu, Rui Xu, Zhi-Kang Lin, Si-Yuan Yu, Ming Bao, Jian-Hua Jiang, Ming-Hui Lu, Yan-Feng Chen
Summary: Despite traditional beliefs, recent research has revealed the rich structures of acoustic waves, including the observation of skyrmion configurations in dynamic acoustic velocity fields. The controllability and robustness of acoustic skyrmion lattices have been demonstrated, potentially offering new technological advancements in the manipulation of small particles.
PHYSICAL REVIEW LETTERS
(2021)
Article
Multidisciplinary Sciences
Di Wu, Diego Baresch, Colin Cook, Zhichao Ma, Mengtong Duan, Dina Malounda, David Maresca, Maria P. Abundo, Justin Lee, Shirin Shivaei, David R. Mittelstein, Tian Qiu, Peer Fischer, Mikhail G. Shapiro
Summary: Ultrasound can manipulate cells with high precision through acoustic radiation force (ARF), but this ability is disconnected from cellular genetic programs due to the similar acoustic properties of most cells. Gas vesicles (GVs), a unique class of gas-filled protein nanostructures, can serve as genetically encodable actuators for selective acoustic manipulation. GVs experience strong ARF with opposite polarity to most other materials due to their lower density and higher compressibility relative to water. When expressed inside cells, GVs invert the cells' acoustic contrast and amplify their ARF, enabling selective manipulation of cells based on their genotype. GVs provide a direct link between gene expression and acoustomechanical actuation, opening up a paradigm for selective cellular control in a broad range of contexts.
Article
Chemistry, Physical
Kuai Yu, Yiqi Jiang, Cameron Wright, Gregory Hartland
Summary: This article provides an overview of the damping of vibrational modes in nanostructures excited by ultrafast laser. It discusses the influence of liquid viscosity and viscoelasticity on energy dissipation, and presents the continuum mechanics theory and experimental measurements of damping. The article focuses on the breathing modes of spheres, cylinders, and plates, and analyzes the differences between different shapes and the dependence of relaxation times on nanostructure dimensions. It also highlights the unique information about nanoscale material properties that can be obtained from the quality factors of the breathing modes.
JOURNAL OF PHYSICAL CHEMISTRY C
(2022)
Article
Biochemical Research Methods
Xianming Qin, Xueyong Wei, Lei Li, Hairong Wang, Zhuangde Jiang, Dong Sun
Summary: The novel concept of acoustic valves in microfluidic channels uses focused acoustic fields to control droplets, eliminating the need for high voltage or sample modification. This non-contact manipulation method is suitable for biochemical experiments with minimal requirements, especially those involving optical observation and chemical reactions.
Article
Multidisciplinary Sciences
Pengzhan Liu, Zhenhua Tian, Kaichun Yang, Ty Downing Naquin, Nanjing Hao, Huiyu Huang, Jinyan Chen, Qiuxia Ma, Hunter Bachman, Peiran Zhang, Xiahong Xu, Junhui Hu, Tony Jun Huang
Summary: Acoustofluidic black holes (AFBHs) are a technology that can slow down and capture acoustic waves, enabling versatile particle manipulation functionalities. This study fills the gap between acoustofluidics and acoustic black holes, leading to potential applications in various fields.
Article
Biochemical Research Methods
Tao Luo, Sirui Liu, Rui Zhou, Chen Zhang, Dongyang Chen, Yi Zhan, Qilin Hu, Xi He, Yu Xie, Zhijie Huan, Wendi Gao, Ruirui Li, Gongfa Yuan, Yancheng Wang, Wei Zhou
Summary: Droplet manipulation on superhydrophobic surfaces using contactless acoustic waves is reported. A contactless acoustic tweezer is developed by establishing an ultrasonic standing wave between an ultrasound transducer and a superhydrophobic substrate. The acoustic radiation forces are utilized to trap and move droplets, allowing for precise and controllable movement.
Article
Multidisciplinary Sciences
Zhike Xu, Ling Qin, Wei Xu, Shuhua Fang, Jiyao Wang
Summary: This paper introduces a metasurface design approach using a perforated labyrinthine path coil structure to manipulate acoustic transmission with adjustable resonance peak frequencies and bandgap width for acoustic metamaterials. The theory is validated through simulations and experiments, demonstrating the accuracy of the proposed design method.
SCIENTIFIC REPORTS
(2021)
Article
Chemistry, Analytical
Ari Leshno, Avraham Kenigsberg, Heli Peleg-Levy, Silvia Piperno, Alon Skaat, Hagay Shpaisman
Summary: This study introduces a novel method utilizing standing acoustic waves to noninvasively manipulate intraocular particles inside the anterior chamber. Experimental results show that this technique does not cause any damage or side effects to ocular tissue, providing a potential tool for preventing secondary glaucoma.
Article
Chemistry, Multidisciplinary
Wenhui Wang, Ivan Erofeev, Ya He, Fangqi Yang, Hongwei Yan, Jiong Lu, Utkur Mirsaidov
Summary: In this study, the formation process of hollow PdCu nanoparticles from Cu2O template nanoparticles is revealed using in situ liquid-phase transmission electron microscopy. It is shown that a polycrystalline PdCu shell forms on the template surface via a galvanic replacement reaction, while the template undergoes anisotropic etching.
Article
Chemistry, Analytical
Yaxing Wang, Liqun Wu, Yajing Wang
Summary: This study designed a test system for internal levitation in three-dimensional space to study the acoustic levitation and manipulation of micro-particles inside heterogeneous structures in metal. Through experimental tests, the relationship between levitation force, particle diameter, and other parameters was established, and a method for controlling particle motion in three-dimensional space was demonstrated. These research results provide an effective processing solution for utilizing the internal spatial structure of metal.
Article
Chemistry, Analytical
Nino F. Laubli, Michael S. Gerlt, Alexander Wuthrich, Renard T. M. Lewis, Naveen Shamsudhin, Ulrike Kutay, Daniel Ahmed, Jurg Dual, Bradley J. Nelson
Summary: Acoustically excited microstructures have shown significant potential for small-scale biomedical applications by overcoming major microfluidic limitations. The embedded microbubble design combines the benefits of solid structures and microbubbles while minimizing their drawbacks, demonstrating capabilities for microfluidic applications such as mixing performance and controlled rotational manipulation of individual cells. This innovative design offers a versatile and efficient solution for industrial and clinical purposes.
ANALYTICAL CHEMISTRY
(2021)
Review
Chemistry, Physical
Meili Qi, Dan Dang, Xieliu Yang, Junhai Wang, Hemin Zhang, Wenfeng Liang
Summary: The introduction of surface acoustic waves (SAWs) has led to the development of a cutting-edge technology-SAW-based micro/nano manipulation in lab-on-a-chip microfluidic systems. This technology has become an important tool for manipulating micro/nano particles/cell populations due to its simplicity, biocompatibility, non-invasiveness, scalability, and versatility. It has been successfully used in applications such as biomedical and point-of-care diagnostic systems. This review paper provides an overview of the working principle and numerical simulation of SAW-based manipulation, recent advancements in the manipulation of organisms, and discusses the challenges and future prospects of SAW-based manipulation.
Article
Chemistry, Physical
Hao Cai, Bolu Zhang, Yong Gan
Summary: The acoustic vibrations of single gold nanorods in water were studied using continuum finite element simulations in the time domain. The results showed that the quality factors of the nanorods were lower due to the fluid, with nonmonotonic dependence on the aspect ratio. The extensional and breathing quality factors of the nanorods increased with the increase of nanorod width for a given aspect ratio.
JOURNAL OF PHYSICAL CHEMISTRY C
(2021)
Article
Chemistry, Physical
Zhenzhen Chen, Zhewei Cai, Wenbo Liu, Zijie Yan
Summary: Optical tweezers can control the position and orientation of individual colloidal particles in solution, providing unique prospects for single-particle spectroscopy and microscopy. This perspective discusses the underlying principles, combinations, and applications of optical tweezers with different spectroscopy and microscopy techniques, as well as the challenges and opportunities for performing spectroscopy and microscopy on single nanoparticles with optical tweezers.
JOURNAL OF CHEMICAL PHYSICS
(2022)
Article
Engineering, Biomedical
Jiahao Fan, Hangyu Zhu, Xinyu Jiang, Long Meng, Chen Chen, Cong Fu, Huan Yu, Chenyun Dai, Wei Chen
Summary: In this study, an unsupervised domain adaptation method called domain statistics alignment (DSA) is proposed to adapt well-trained models from large-scale datasets to small sleep cohorts. By modulating domain-specific statistics of deep features, DSA improves the performance of source models on target domains. The proposed methods are validated on multiple sleep databases, demonstrating significant performance improvement on target domains.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2022)
Article
Acoustics
Wei Zhou, Xinhui Wang, Kaiyue Wang, Umar Farooq, Lijun Kang, Lili Niu, Long Meng
Summary: This article demonstrates the behavioral response of Caenorhabditis elegans to ultrasound stimulation mediated by the activation of mechanical sensitive MEC-4 and MEC-6 ion channels. Mutant worms with specific mutations in these ion channels show a significant decrease in behavioral response compared to the wild type. Additionally, it is found that ultrasound stimulation can directly activate neurons expressing MEC-4 and MEC-6 ion channels.
IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL
(2022)
Article
Biochemical Research Methods
Xiufang Liu, Wenjun Zhang, Umar Farooq, Ning Rong, Jingyao Shi, Na Pang, Lisheng Xu, Lili Niu, Long Meng
Summary: This study demonstrates an effective strategy for cell capture, pairing, and fusion based on oscillating bubbles within an acoustofluidic device. The method allows for efficient and quick cell pairing and fusion, and the fused cells maintain important biological functions.
Article
Chemistry, Multidisciplinary
Peng-Qi Li, Zong-Lin Li, Wei Zhou, Shengwu Wang, Long Meng, Yu-Gui Peng, Zhi Chen, Hairong Zheng, Xue-Feng Zhu
Summary: Metasurfaces of subwavelength thicknesses can manipulate acoustic waves, and multistructured underwater ultrasound can be generated through self-assembly deposition, enabling low-threshold and contactless behavior control.
ADVANCED FUNCTIONAL MATERIALS
(2022)
Article
Engineering, Biomedical
Long Meng, Qiong Chen, Xinyu Jiang, Xiangyu Liu, Jiahao Fan, Chenyun Dai, Wei Chen
Summary: This study provides a guide for researchers to determine proper decomposition parameters for sEMG decomposition-related works, increasing understanding of the influences between computation time and decomposition performance.
BIOMEDICAL SIGNAL PROCESSING AND CONTROL
(2022)
Article
Metallurgy & Metallurgical Engineering
Ziyang Xu, Guangye Wei, Zhihui Yu, Long Meng, Shili Zheng, Jingkui Qu, Tao Qi
Summary: This paper presents a method for separating large amounts of Mn and Mg from Ni and Co chloride solution by microbubble aeration oxidation and acid leaching processes. Under optimal experimental conditions, high recovery efficiency of Ni and Co and high removal efficiency of Mn and Mg were achieved. The reaction mechanism was investigated through various analysis methods.
Article
Psychiatry
Sha-sha Yi, Jun-jie Zou, Long Meng, Hou-minji Chen, Zhong-qiu Hong, Xiu-fang Liu, Umar Farooq, Mo-xian Chen, Zheng-rong Lin, Wei Zhou, Li-juan Ao, Xi-quan Hu, Li-li Niu
Summary: Research shows that ultrasound stimulation of the prefrontal cortex can suppress inflammation and improve depressive and anxiety-like behaviors, potentially offering a non-invasive treatment option for neuropsychiatric diseases.
FRONTIERS IN PSYCHIATRY
(2022)
Article
Computer Science, Information Systems
Haikang Diao, Chen Chen, Xiangyu Liu, Wei Yuan, Amara Amara, Toshiyo Tamura, Benny Lo, Jiahao Fan, Long Meng, Sio Hang Pun, Yuan-Ting Zhang, Wei Chen
Summary: This article proposes a real-time and low-cost smart mat system that recognizes sleep postures through frequency channel selection. The feasibility and reliability of the system are evaluated through experiments, showing high accuracy, small model size, and low runtime. The proposed system has the potential to contribute to the development of fast, convenient, and low-cost sleep posture recognition products for IoMT.
IEEE INTERNET OF THINGS JOURNAL
(2022)
Article
Computer Science, Information Systems
Xinyu Jiang, Long Meng, Xiangyu Liu, Jiahao Fan, Xinming Ye, Chenyun Dai, Wei Chen
Summary: This study aims to optimize the cross-day performance of the surface electromyogram (sEMG) biometric decoder. By evaluating different hand gestures, feature combinations, and classifiers, the optimal combination of features and decoder were identified, achieving good cross-day verification and identification performance.
IEEE INTERNET OF THINGS JOURNAL
(2023)
Article
Multidisciplinary Sciences
Yaya Zhang, Na Pang, Xiaowei Huang, Wen Meng, Long Meng, Bingchang Zhang, Zhengye Jiang, Jing Zhang, Zhou Yi, Zhiyu Luo, Zhanxiang Wang, Lili Niu
Summary: The study found that noninvasive ultrasound deep brain stimulation (UDBS) can decelerate telomere shortening and improve aging and aging-related diseases. This method has significant effects on both normal mice and aging mice by activating telomerase-associated proteins and upregulating the neuroactive ligand-receptor interaction pathway.
FUNDAMENTAL RESEARCH
(2023)
Article
Engineering, Biomedical
Zheng Zeng, Yan Xu, Chen Chen, Ligang Zhou, Yalin Wang, Minghui Liu, Long Meng, Yuanfeng Zhou, Wei Chen
Summary: This study proposes a reliable assessment method to differentiate between drug-sensitive epilepsy and drug-resistant epilepsy caused by KCNQ2 pathogenic variants. By analyzing EEG and EOG signals, 24 features were extracted and the Gradient Boosting Decision Tree was used for classification. With selected channels and features, the classification accuracy can reach 81.25%, indicating the superiority of the proposed method.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2023)
Proceedings Paper
Computer Science, Artificial Intelligence
Qi Fu, Long Meng, Haibo Qin, Chen Chen, Anjing Zhang, Chen Wei
Summary: Stroke survivors can benefit from personalized treatment, and this paper proposes an unobtrusive upper-limb movement recognition system for them based on model fusion. The system achieves high accuracy in hand gesture recognition and is expected to assist rehabilitation physicians in providing better-personalized treatment.
2022 9TH INTERNATIONAL CONFERENCE ON BIOMEDICAL AND BIOINFORMATICS ENGINEERING, ICBBE 2022
(2022)
Article
Engineering, Electrical & Electronic
Long Meng, Xinyu Jiang, Xiangyu Liu, Jiahao Fan, Haoran Ren, Yao Guo, Haikang Diao, Zihao Wang, Chen Chen, Chenyun Dai, Wei Chen
Summary: This study investigates the application of sEMG-based hand gesture recognition for prosthesis or armband in the human-machine interface. The experiment finds that the measurement location greatly influences the accuracy of gesture recognition. Therefore, the study provides a factor-screening tool to help users customize their systems according to their physical conditions and requirements.
IEEE TRANSACTIONS ON INSTRUMENTATION AND MEASUREMENT
(2022)
Proceedings Paper
Computer Science, Theory & Methods
M. Caballero, D. Kavallieros, A. Spyros, A. Tavernarakisv, A. Tziouvaras, S. Bonacina, K. Chandrarmouli, M. Coroiu, L. Chen, T. Dounia, I Giannoulakis, N. Gligoric, E. Kafetzakis, T. Kasig, V Koumaras, T. Krousarlis, K. Lapidaki, A. Markakis, S. Marin, M. Manulis, S. Menesidou, S. Nifakos, L. Meng, S. Mhiri, M. Nati, K. Ntafloukas, D. Oniga, D. Papamartzivanos, S. Papastergiou, K. Sanchez, C. Sakkas, K. Stelliou, L. Trujillo, T. Tsikrika, E. Venegas, S. Vrochidis, D. Xydias
Summary: The industrial sector is undergoing unprecedented changes, with potential impacts of cybersecurity breaches reaching new levels. The SECANT project aims to enhance understanding of risks and provide a holistic framework for cyber security risk assessment to improve digital security, privacy, and personal data protection.
2022 IEEE INTERNATIONAL CONFERENCE ON CYBER SECURITY AND RESILIENCE (IEEE CSR)
(2022)
Article
Engineering, Biomedical
Yao Guo, Xinyu Jiang, Linkai Tao, Long Meng, Chenyun Dai, Xi Long, Feng Wan, Yuan Zhang, Johannes van Dijk, Ronald M. Aarts, Wei Chen, Chen Chen
Summary: This study proposes a hybrid system combining unsupervised learning and supervised learning modules for automatic detection of epilepsy seizures. By utilizing the unsupervised learning module, the workload of data labelling can be significantly reduced. The proposed system is evaluated using the CHB-MIT scalp EEG dataset and achieves a competitive performance.
IEEE TRANSACTIONS ON NEURAL SYSTEMS AND REHABILITATION ENGINEERING
(2022)
