Gentle, fast and effective crystal soaking by acoustic dispensing

TheXChemExplorergraphical workflow tool for routine or large-scale protein–ligand structure determination

(2017) Tobias Krojer et al.   Acta Crystallographica Section D-Structural Biology

AceDRG: a stereochemical description generator for ligands

(2017) Fei Long et al.   Acta Crystallographica Section D-Structural Biology

Six Biophysical Screening Methods Miss a Large Proportion of Crystallographically Discovered Fragment Hits: A Case Study

(2016) Johannes Schiebel et al.   ACS Chemical Biology

8-Substituted Pyrido[3,4-d]pyrimidin-4(3H)-one Derivatives As Potent, Cell Permeable, KDM4 (JMJD2) and KDM5 (JARID1) Histone Lysine Demethylase Inhibitors

(2016) Vassilios Bavetsias et al.   JOURNAL OF MEDICINAL CHEMISTRY

Twenty years on: the impact of fragments on drug discovery

(2016) Daniel A. Erlanson et al.   NATURE REVIEWS DRUG DISCOVERY

Acoustic Injectors for Drop-On-Demand Serial Femtosecond Crystallography

(2016) Christian G. Roessler et al.   STRUCTURE

Diffraction-geometry refinement in theDIALSframework

(2016) David G. Waterman et al.   Acta Crystallographica Section D-Structural Biology

Lessons from ten years of crystallization experiments at the SGC

(2016) Jia Tsing Ng et al.   Acta Crystallographica Section D-Structural Biology

Automated harvesting and processing of protein crystals through laser photoablation

(2016) Ulrich Zander et al.   Acta Crystallographica Section D-Structural Biology

High throughput screening using acoustic droplet ejection to combine protein crystals and chemical libraries on crystallization plates at high density

(2015) Ella Teplitsky et al.   JOURNAL OF STRUCTURAL BIOLOGY

Acoustic transfer of protein crystals from agarose pedestals to micromeshes for high-throughput screening

(2015) Christina M. Cuttitta et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Combining `dry' co-crystallization andin situdiffraction to facilitate ligand screening by X-ray crystallography

(2015) Muriel Gelin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

DIMPLE- a pipeline for the rapid generation of difference maps from protein crystals with putatively bound ligands

(2015) Marcin Wojdyr et al.   ACTA CRYSTALLOGRAPHICA SECTION A

Advantages of crystallographic fragment screening: Functional and mechanistic insights from a powerful platform for efficient drug discovery

(2014) Disha Patel et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

Using textons to rank crystallization droplets by the likely presence of crystals

(2014) Jia Tsing Ng et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Hitting the target: fragment screening with acousticin situco-crystallization of proteins plus fragment libraries on pin-mounted data-collection micromeshes

(2014) Xingyu Yin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A simple technique to reduce evaporation of crystallization droplets by using plate lids with apertures for adding liquids

(2014) Lauren E. Zipper et al.   Acta Crystallographica Section F-Structural Biology Communications

Detecting Allosteric Sites of HIV-1 Reverse Transcriptase by X-ray Crystallographic Fragment Screening

(2013) Joseph D. Bauman et al.   JOURNAL OF MEDICINAL CHEMISTRY

Nanolitre-scale crystallization using acoustic liquid-transfer technology

(2012) Armando G. Villaseñor et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Direct cryocooling of naked crystals: are cryoprotection agents always necessary?

(2011) Erika Pellegrini et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Overview of theCCP4 suite and current developments

(2011) Martyn D. Winn et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

xia2: an expert system for macromolecular crystallography data reduction

(2009) G. Winter   JOURNAL OF APPLIED CRYSTALLOGRAPHY