TNFα-YAP/p65-HK2 axis mediates breast cancer cell migration

CGI-99 promotes breast cancer metastasis via autocrine interleukin-6 signaling

(2017) C Lin et al.   ONCOGENE

YAP–IL-6ST autoregulatory loop activated on APC loss controls colonic tumorigenesis

(2017) Koji Taniguchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TNF-α Modulation of Intestinal Tight Junction Permeability Is Mediated by NIK/IKK-α Axis Activation of the Canonical NF-κB Pathway

(2016) Rana Al-Sadi et al.   AMERICAN JOURNAL OF PATHOLOGY

The SRF-YAP-IL6 axis promotes breast cancer stemness

(2016) Tackhoon Kim et al.   CELL CYCLE

Osmotic stress‐induced phosphorylation by NLK at Ser128 activates YAP

(2016) Audrey W Hong et al.   EMBO REPORTS

Phosphorylation by NLK inhibits YAP‐14‐3‐3‐interactions and induces its nuclear localization

(2016) Sungho Moon et al.   EMBO REPORTS

TNFα-activated mesenchymal stromal cells promote breast cancer metastasis by recruiting CXCR2+ neutrophils

(2016) P F Yu et al.   ONCOGENE

Tead and AP1 Coordinate Transcription and Motility

(2016) Xiangfan Liu et al.   Cell Reports

TNF-α-Induced NF-κB Activation Stimulates Skeletal Muscle Glycolytic Metabolism Through Activation of HIF-1α

(2015) A. H. V. Remels et al.   ENDOCRINOLOGY

A gp130–Src–YAP module links inflammation to epithelial regeneration

(2015) Koji Taniguchi et al.   NATURE

Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway

(2015) Jung-Soon Mo et al.   NATURE CELL BIOLOGY

Genome-wide association between YAP/TAZ/TEAD and AP-1 at enhancers drives oncogenic growth

(2015) Francesca Zanconato et al.   NATURE CELL BIOLOGY

AMPK modulates Hippo pathway activity to regulate energy homeostasis

(2015) Wenqi Wang et al.   NATURE CELL BIOLOGY

Quantitative analysis of the TNF-α-induced phosphoproteome reveals AEG-1/MTDH/LYRIC as an IKKβ substrate

(2015) Ramesh K. Krishnan et al.   Nature Communications

A basal-like breast cancer-specific role for SRF–IL6 in YAP-induced cancer stemness

(2015) Tackhoon Kim et al.   Nature Communications

A TEAD1/p65 complex regulates the eutherian-conserved MnSOD intronic enhancer, eRNA transcription and the innate immune response

(2014) Ann L. Chokas et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer

(2014) Avnish Kapoor et al.   CELL

Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase

(2014) Biao Ma et al.   NATURE CELL BIOLOGY

Energy Stress Regulates Hippo-YAP Signaling Involving AMPK-Mediated Regulation of Angiomotin-like 1 Protein

(2014) Michael DeRan et al.   Cell Reports

The tumor microenvironment at a glance

(2013) F. R. Balkwill et al.   JOURNAL OF CELL SCIENCE

LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker

(2012) Dahu Chen et al.   NATURE MEDICINE

The Hippo pathway target, YAP, promotes metastasis through its TEAD-interaction domain

(2012) J. M. Lamar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF -TRCP

(2010) B. Zhao et al.   GENES & DEVELOPMENT

Specification of the NF-κB transcriptional response by p65 phosphorylation and TNF-induced nuclear translocation of IKKε

(2010) Rita Moreno et al.   NUCLEIC ACIDS RESEARCH

YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation

(2009) A. Fernandez-L et al.   GENES & DEVELOPMENT

c-Jun N-terminal Kinase Enhances MST1-mediated Pro-apoptotic Signaling through Phosphorylation at Serine 82

(2009) Wenzhi Bi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Negative Regulation of YAP by LATS1 Underscores Evolutionary Conservation of the Drosophila Hippo Pathway

(2008) J. Zhang et al.   CANCER RESEARCH

TEAD mediates YAP-dependent gene induction and growth control

(2008) B. Zhao et al.   GENES & DEVELOPMENT

Mst2 and Lats Kinases Regulate Apoptotic Function of Yes Kinase-associated Protein (YAP)

(2008) Tsutomu Oka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Tumour immunity: effector response to tumour and role of the microenvironment

(2008) Alberto Mantovani et al.   LANCET