期刊
NANOMATERIALS
卷 7, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/nano7060148
关键词
multifunctional nanoparticle; antioxidant activity; antibacterial activity; caffeic acid; ZnO
类别
资金
- Chosun University
- National Research Foundation of Korea - Korean government (MSIP) [NRF-2015M3A9E2066855, NRF-2015M3A9E2066856]
- National Research Foundation of Korea [NRF-2014R1A1A2054928, 2014H1C1A10669352014]
- National Research Foundation of Korea [2014H1C1A1066935, 2015M3A9E2066856, 2015M3A9E2066855] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)
We report a novel zinc oxide (ZnO) nanoparticle with antioxidant properties, prepared by immobilizing the antioxidant 3-(3,4-dihydroxyphenyl)-2-propenoic acid (caffeic acid, CA) on the surfaces of micro-dielectric barrier discharge (DBD) plasma-treated ZnO nanoparticles. The microstructure and physical properties of ZnO@CA nanoparticles were characterized by field emission scanning electron microscopy (FESEM), transmission electron microscopy (TEM), infrared spectroscopy, and steady state spectroscopic methods. The antioxidant activity of ZnO@CA nanoparticles was evaluated using an ABTS (3-ethyl-benzothiazoline-6-sulfonic acid) radical cation decolorization assay. ZnO@CA nanoparticles exhibited robust antioxidant activity. Moreover, ZnO@CA nanoparticles showed strong antibacterial activity against Gram-positive bacteria (Staphylococcus aureus) including resistant bacteria such as methicillin-resistant S. aureus and against Gram-negative bacteria (Escherichia coli). Although Gram-negative bacteria appeared to be more resistant to ZnO@CA nanoparticles than Gram-positive bacteria, the antibacterial activity of ZnO@CA nanoparticles was dependent on particle concentration. The antioxidant and antibacterial activity of ZnO@CA may be useful for various biomedical and nanoindustrial applications.
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