Regulation of Pulmonary Vascular Smooth Muscle Contractility in Pulmonary Arterial Hypertension: Implications for Therapy

Vascular Smooth Muscle Cells in Atherosclerosis

(2016) Martin R. Bennett et al.   CIRCULATION RESEARCH

Gene therapy for the treatment of heart failure: promise postponed

(2016) Jean-Sebastien Hulot et al.   EUROPEAN HEART JOURNAL

Initial dual oral combination therapy in pulmonary arterial hypertension

(2016) Olivier Sitbon et al.   EUROPEAN RESPIRATORY JOURNAL

Calcium upregulation by percutaneous administration of gene therapy in patients with cardiac disease (CUPID 2): a randomised, multinational, double-blind, placebo-controlled, phase 2b trial

(2016) Barry Greenberg et al.   LANCET

Changes in ventricular remodelling and clinical status during the year following a single administration of stromal cell-derived factor-1 non-viral gene therapy in chronic ischaemic heart failure patients: the STOP-HF randomized Phase II trial

(2015) Eugene S. Chung et al.   EUROPEAN HEART JOURNAL

Lipid nanoparticle delivery of a microRNA-145 inhibitor improves experimental pulmonary hypertension

(2015) Jared M. McLendon et al.   JOURNAL OF CONTROLLED RELEASE

Management of Pulmonary Arterial Hypertension

(2015) Vallerie V. McLaughlin et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Initial Use of Ambrisentan plus Tadalafil in Pulmonary Arterial Hypertension

(2015) Nazzareno Galiè et al.   NEW ENGLAND JOURNAL OF MEDICINE

PKG-1α leucine zipper domain defect increases pulmonary vascular tone: implications in hypoxic pulmonary hypertension

(2014) Ramaswamy Ramchandran et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Differential phosphorylation of LZ+/LZ− MYPT1 isoforms regulates MLC phosphatase activity

(2014) Samantha L. Yuen et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Attenuation of Monocrotaline-Induced Pulmonary Hypertension by Luminal Adeno-Associated Virus Serotype 9 Gene Transfer of Prostacyclin Synthase

(2014) Igor B. Gubrij et al.   HUMAN GENE THERAPY

The role of pulmonary vascular contractile protein expression in pulmonary arterial hypertension

(2013) Ewa A. Konik et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Updated Clinical Classification of Pulmonary Hypertension

(2013) Gerald Simonneau et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Riociguat for the Treatment of Pulmonary Arterial Hypertension

(2013) Hossein-Ardeschir Ghofrani et al.   NEW ENGLAND JOURNAL OF MEDICINE

Protein Kinase G-I Deficiency Induces Pulmonary Hypertension through Rho A/Rho Kinase Activation

(2012) Yidan D. Zhao et al.   AMERICAN JOURNAL OF PATHOLOGY

Inflammation in Pulmonary Arterial Hypertension

(2012) Laura C. Price et al.   CHEST

An Evaluation of Long-term Survival From Time of Diagnosis in Pulmonary Arterial Hypertension From the REVEAL Registry

(2012) Raymond L. Benza et al.   CHEST

Gene Transfer Therapy by Either Type 1 or Type 2 Adeno-Associated Virus Expressing Human Prostaglandin I2 Synthase Gene is Effective for Treatment of Pulmonary Arterial Hypertension

(2012) Masaharu Kataoka et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY AND THERAPEUTICS

Cyclic guanosine monophosphate signalling pathway in pulmonary arterial hypertension

(2012) Chien-nien Chen et al.   VASCULAR PHARMACOLOGY

Hypoxia Modulates the Expression of Leucine Zipper-Positive MYPT1 and its Interaction with Protein Kinase G and Rho Kinases in Pulmonary Arterial Smooth Muscle Cells

(2012) Dev K. Singh et al.   Pulmonary Circulation

Calcium Upregulation by Percutaneous Administration of Gene Therapy in Cardiac Disease (CUPID)

(2011) Mariell Jessup et al.   CIRCULATION

MYPT1 Protein Isoforms Are Differentially Phosphorylated by Protein Kinase G

(2011) Samantha Yuen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Integration of Clinical and Hemodynamic Parameters in the Prediction of Long-term Survival in Patients With Pulmonary Arterial Hypertension

(2010) Garvan C. Kane et al.   CHEST

Formation of Plexiform Lesions in Experimental Severe Pulmonary Arterial Hypertension

(2010) Kohtaro Abe et al.   CIRCULATION

Basic Science of Pulmonary Arterial Hypertension for Clinicians

(2010) Stephen L. Archer et al.   CIRCULATION

Fasudil reduces monocrotaline-induced pulmonary arterial hypertension: comparison with bosentan and sildenafil

(2010) K. T. B. Mouchaers et al.   EUROPEAN RESPIRATORY JOURNAL

Nonmuscle myosin is regulated during smooth muscle contraction

(2009) Samantha L. Yuen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Animal models of pulmonary arterial hypertension: the hope for etiological discovery and pharmacological cure

(2009) Kurt R. Stenmark et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Regulation of Cellular Protein Phosphatase-1 (PP1) by Phosphorylation of the CPI-17 Family, C-kinase-activated PP1 Inhibitors

(2009) Masumi Eto   JOURNAL OF BIOLOGICAL CHEMISTRY

Pulmonary Vascular Disease in the Developing World

(2008) Ghazwan Butrous et al.   CIRCULATION