Cardiac Subtype-Specific Modeling of Kv1.5 Ion Channel Deficiency Using Human Pluripotent Stem Cells

Perspectives and Challenges of Pluripotent Stem Cells in Cardiac Arrhythmia Research

(2017) Alexander Goedel et al.   Current Cardiology Reports

Human iPS cell model of type 3 long QT syndrome recapitulates drug-based phenotype correction

(2016) Daniela Malan et al.   BASIC RESEARCH IN CARDIOLOGY

Rigorous Phenotyping of Cardiac iPSC Preparations Requires Knowledge of Their Resting Potential(s)

(2016) Wayne R. Giles et al.   BIOPHYSICAL JOURNAL

Atrial Fibrillation Genetics: Is There a Practical Clinical Value Now or in the Future?

(2016) William J. Hucker et al.   CANADIAN JOURNAL OF CARDIOLOGY

Functional Characterization of Rare Variants Implicated in Susceptibility to Lone Atrial Fibrillation

(2015) Kenshi Hayashi et al.   Circulation-Arrhythmia and Electrophysiology

Atrial-like cardiomyocytes from human pluripotent stem cells are a robust preclinical model for assessing atrial-selective pharmacology

(2015) H. D. Devalla et al.   EMBO Molecular Medicine

Genetics of atrial fibrillation: from families to genomes

(2015) Ingrid E Christophersen et al.   JOURNAL OF HUMAN GENETICS

Defining the major health modifiers causing atrial fibrillation: a roadmap to underpin personalized prevention and treatment

(2015) Larissa Fabritz et al.   Nature Reviews Cardiology

Universal Cardiac Induction of Human Pluripotent Stem Cells in Two and Three-Dimensional Formats: Implications for In Vitro Maturation

(2015) Miao Zhang et al.   STEM CELLS

Ion channelopathies in human induced pluripotent stem cell derived cardiomyocytes: a dynamic clamp study with virtual IK1

(2015) Rosalie M. E. Meijer van Putten et al.   Frontiers in Physiology

Light-induced termination of spiral wave arrhythmias by optogenetic engineering of atrial cardiomyocytes

(2014) Brian O. Bingen et al.   CARDIOVASCULAR RESEARCH

Cardiac Potassium Channel Subtypes: New Roles in Repolarization and Arrhythmia

(2014) Nicole Schmitt et al.   PHYSIOLOGICAL REVIEWS

Recessive cardiac phenotypes in induced pluripotent stem cell models of Jervell and Lange-Nielsen syndrome: Disease mechanisms and pharmacological rescue

(2014) Miao Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Efficient Generation of Human iPSCs by a Synthetic Self-Replicative RNA

(2013) Naohisa Yoshioka et al.   Cell Stem Cell

J-Shaped Association Between QTc Interval Duration and the Risk of Atrial Fibrillation

(2013) Jonas Bille Nielsen et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Genetic variation in KCNA5: impact on the atrial-specific potassium current IKur in patients with lone atrial fibrillation

(2012) Ingrid E. Christophersen et al.   EUROPEAN HEART JOURNAL

Small Molecule-Assisted, Line-Independent Maintenance of Human Pluripotent Stem Cells in Defined Conditions

(2012) Stefan Frank et al.   PLoS One

Induced pluripotent stem cell derived cardiomyocytes as models for cardiac arrhythmias

(2012) Maaike Hoekstra et al.   Frontiers in Physiology

PITX2c Is Expressed in the Adult Left Atrium, and Reducing Pitx2c Expression Promotes Atrial Fibrillation Inducibility and Complex Changes in Gene Expression

(2011) Paulus Kirchhof et al.   Circulation-Cardiovascular Genetics

FGF signalling inhibits neural induction in human embryonic stem cells

(2011) Boris Greber et al.   EMBO JOURNAL

2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation

(2011) Valentin Fuster et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Pathophysiological Mechanisms of Atrial Fibrillation: A Translational Appraisal

(2011) Ulrich Schotten et al.   PHYSIOLOGICAL REVIEWS

Phase Mapping of Cardiac Fibrillation

(2010) Karthikeyan Umapathy et al.   Circulation-Arrhythmia and Electrophysiology

Association Between Familial Atrial Fibrillation and Risk of New-Onset Atrial Fibrillation

(2010) Steven A. Lubitz et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Novel KCNA5 loss-of-function mutations responsible for atrial fibrillation

(2009) Yiqing Yang et al.   JOURNAL OF HUMAN GENETICS

Prevalence of early-onset atrial fibrillation in congenital long QT syndrome

(2008) Jonathan N. Johnson et al.   HEART RHYTHM

Status of the Epidemiology of Atrial Fibrillation

(2007) William B. Kannel et al.   MEDICAL CLINICS OF NORTH AMERICA